Results 71 to 80 of about 42,850 (196)

Biosynthesis of the fungal metabolite tenellin [PDF]

, 2000
This thesis concerns the biosynthesis of tenellin, a bright yellow secondary metabolite of the fungus Beauveria bassiana. Several putative intermediates have been synthesised and feeding experiments performed in order to provide some insight into the ...
Smith, Helen K.
core  

The Crystal Structure of the actIII Actinorhodin Polyketide Reductase: Proposed Mechanism for ACP and Polyketide Binding. [PDF]

, 2004
We have determined the 2.5 Å crystal structure of an active, tetrameric Streptomyces coelicolor type II polyketide ketoreductase (actIII) with its bound cofactor, NADP+.
Simpson, Thomas J., Limpkin, Claire, Limpkin C, Crosby J, Crump MP, Hadfield AT, Crosby, John, Crump, Matthew P., Teartasin W, Hadfield, Andrea T., Simpson TJ, Teartasin, Watchrra   +11 more
core   +1 more source

polyketides

, 2014
Citation: 'polyketides' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.P04734 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

MCAT is not required for in vitro polyketide synthesis in a minimal actinorhodin polyketide synthase from Streptomyces coelicolor [PDF]

, 1998
Background: It has been proposed that Streptomyces malonyl CoA:holo acyl carrier protein transacylases (MCATs) provide a link between fatty acid and polyketide biosynthesis. Two recent studies have provided evidence that the presence of MCAT is essential
Simpson, Thomas J., Crosby, John, Matharu, Anne-Lise, Byrom, Kate J., Cox, Russell J.   +4 more
core   +1 more source

The unusual mode of action of the polyketide glycoside antibiotic cervimycin C

mSphere
Cervimycins A–D are bis-glycosylated polyketide antibiotics produced by Streptomyces tendae HKI 0179 with bactericidal activity against Gram-positive bacteria.
Alina Hoffmann, Ursula Steffens, Boris Maček, Mirita Franz-Wachtel, Kay Nieselt, Theresa Anisja Harbig, Kirstin Scherlach, Christian Hertweck, Hans-Georg Sahl, Gabriele Bierbaum   +9 more
doaj   +1 more source

Polyketides with a 6/6/6/6 Oxaphenalene Pyranone Skeleton from Marine-Derived Streptomyces sp. HDN150000

Marine Drugs
Three new structures named naphpyrone I–K (1–3) that contain a 6/6/6/6 oxaphenalene pyranone skeleton were isolated and purified from a marine-derived Streptomyces sp. HDN155000.
Xiaoting Zhang, Falei Zhang, Wenxue Wang, Xingtao Ren, Tianjiao Zhu, Qian Che, Dehai Li, Guojian Zhang   +7 more
doaj   +1 more source

Arohynapene A Produced by Penicillium steckii JB-NW-2-1 Isolated from Avicennia marina (Forssk.) Vierh and Its Cytotoxic Activities

Indonesian Journal of Chemistry
Mangrove-associated endophytic fungi are producers of secondary metabolites in unique and diverse structures with interesting biological activities such as antiviral, antifungal, antibacterial, anti-inflammatory, and cytotoxic agents.
Yeni Mulyani, Wahyu Syafriansyah, Asri Peni Wulandari, Azmi Azhari, Sari Purbaya, Aprilia Permata Sari, Galih Bayu Pratama, Fajar Fauzi Abdullah, Kindi Farabi, Unang Supratman, Yoshihito Shiono   +10 more
doaj   +1 more source

New Chromones from a Marine-Derived Fungus, Arthrinium sp., and Their Biological Activity

Molecules, 2018
Five new chromone derivatives, arthones A–E (1–5), together with eight known biogenetically related cometabolites (6–13), were isolated from a deep-sea-derived fungus Arthrinium sp. UJNMF0008.
Jie Bao, Fei He, Jin-Hai Yu, Huijuan Zhai, Zhi-Qiang Cheng, Cheng-Shi Jiang, Yuying Zhang, Yun Zhang, Xiaoyong Zhang, Guangying Chen, Hua Zhang   +10 more
doaj   +1 more source

Trichophycin A, a Cytotoxic Linear Polyketide Isolated from a Trichodesmium thiebautii Bloom

Marine Drugs, 2017
In an effort to isolate and characterize bioactive secondary metabolites from Trichodesmium thiebautii blooms, collected cyanobacteria biomass was subjected to bioassay-guided extraction and fractionation using the human colon cancer cell line HCT-116 ...
Matthew J. Bertin, Paul G. Wahome, Paul V. Zimba, Haiyin He, Peter D. R. Moeller   +4 more
doaj   +1 more source

On the Chemistry, Toxicology and Genetics of the Cyanobacterial Toxins, Microcystin, Nodularin, Saxitoxin and Cylindrospermopsin

Marine Drugs, 2010
The cyanobacteria or “blue-green algae”, as they are commonly termed, comprise a diverse group of oxygenic photosynthetic bacteria that inhabit a wide range of aquatic and terrestrial environments, and display incredible morphological diversity.
Leanne Pearson, Troco Mihali, Michelle Moffitt, Ralf Kellmann, Brett Neilan   +4 more
doaj   +1 more source