Results 91 to 100 of about 30,531 (224)

Biosynthetic origin of butyrolactol A, an antifungal polyketide produced by a marine-derived Streptomyces

open access: yesBeilstein Journal of Organic Chemistry, 2017
Butyrolactol A is an antifungal polyketide of Streptomyces bearing an uncommon tert-butyl starter unit and a polyol system in which eight hydroxy/acyloxy carbons are contiguously connected.
Enjuro Harunari   +2 more
doaj   +1 more source

Overlooked components of lipid metabolism: Odd‐chain polyunsaturated fatty acids in photosynthetic microorganisms

open access: yesJournal of Phycology, EarlyView.
Abstract This mini‐review examines odd‐carbon polyunsaturated fatty acids (odd‐PUFAs), a rare but biologically significant group of fatty acids in photosynthetic microorganisms. Odd‐PUFAs are straight‐chain fatty acids containing an odd number of carbon atoms and two or more methylene‐interrupted double bonds. They typically account for less than 1% of
Linda Nedbalová   +2 more
wiley   +1 more source

Marine fungi as a goldmine for novel antibiotics: a 2024 perspective

open access: yesFrontiers in Marine Science
The microbial diversity in oceans is considerable, widely distributed in seawater, marine sediments, and marine organisms. Compared with terrestrial resources in traditional natural product research, the living environments of marine microorganisms are ...
Chengqian Pan   +3 more
doaj   +1 more source

Methyl Jasmonate Seed Priming Mitigates the Defence‐Growth Trade‐Off and Tailors Plant Response to Specific Pests

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Seed defence priming is emerging as a novel, cost‐efficient and environmentally safe tool for pest management. It has been proposed as a means to uncouple the defence‐growth trade‐off in plants by enhancing defence responses with minimal fitness costs, but the mechanisms underlying this role remain elusive.
Lucia Talavera‐Mateo   +5 more
wiley   +1 more source

Cracking the Polyketide Code

open access: yesPLoS Biology, 2004
Polyketides, natural products from microorganisms, have been a main source of antibiotics. Understanding the 'programming' of the enzymes that produce these complex molecules has opened a new field of drug ...
openaire   +4 more sources

Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor   +4 more
wiley   +1 more source

Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee   +5 more
wiley   +1 more source

Alkoxyallenes in Modern Synthesis: Reactivity, Catalysis, and Complexity Generation

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 17, 1 September 2026.
The last decade has witnessed a remarkable transformation in alkoxyallene chemistry. Although historically employed as synthetic equivalents of acrolein or as versatile 3C synthons, alkoxyallenes are now increasingly recognized as highly adaptable platforms for synthetic design.
A. Lanfranco   +5 more
wiley   +1 more source

Elucidating the Molecular Mechanisms of Vitex negundo L. in Polycystic Ovary Syndrome via Metabolomics‐Driven Network Pharmacology

open access: yesBiomedical Chromatography, Volume 40, Issue 9, September 2026.
ABSTRACT Polycystic ovary syndrome (PCOS) is a hormonal disorder marked by irregular menstrual cycles, elevated androgen levels, ovarian cysts, hirsutism, acne and other symptoms. While conventional medications such as Metformin and Spironolactone are commonly prescribed, they are often associated with undesirable side effects.
Nishmitha R. Poojary   +4 more
wiley   +1 more source

Beyond the Classics: The Synergy of AI and Genomics Reveals an Expanded Repertoire of Pigmentation Genes

open access: yesJournal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 6, Page 475-486, September 2026.
Classical approaches for coloration analysis are limited by human low‐resolution phenotyping and genetic analysis. Artificial intelligence allows us to find genes beyond the tip of the iceberg that explain color and pattern diversity in nature. ABSTRACT Pigmentation has long served as a powerful system for exploring gene–trait relationships, yet much ...
Ehsan Pashay Ahi, Nidal Karagic
wiley   +1 more source

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