Results 111 to 120 of about 3,588,030 (299)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Computer simulation of marker-assisted selection utilizing linkage disequilibrium. [PDF]
, 2006 Thesis (M.Sc.)-University of KwaZulu-Natal, Pietermaritzburg, 2006.The face of animal breeding has changed significantly over the past few decades.
Keildson, Sarah.
core +1 more source
Вавиловский журнал генетики и селекции, 2014 Over the past decades, wide theoretical and practical experience has been obtained in application of DNA markers for investigation of plant genetic diversity, construction of molecular genetic maps, mapping of genes and quantitative trait loci, and ...
I. N. Leonova
doaj
FishesWalleye Sander vitreus is a valued sportfish in eastern North America, including the upper New River of Virginia, where individuals can grow to a large size (>7 kg).
Sheila Harris +4 more
doaj +1 more source
Marker‐assisted selection in cattle
Animal Biotechnology, 1992 Abstract Direct observation of genetic differences using molecular techniques has prompted investigation into the nature and amount of genetic variation in cattle. Utilization of molecular data will include parentage analysis, individual identification, sexing of embryos and clones and detection of genetic defects.
openaire +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
The Scientific World Journal, 2014 Pearl millet is a staple food crop for millions of people living in the arid and semi-arid tropics. Molecular markers have been used to identify genomic regions linked to traits of interest by conventional QTL mapping and association analysis. Phenotypic
Baskaran Kannan +6 more
doaj +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Molecular marker-assisted selection for seedlessness in atemoya breeding
Crop Breeding and Applied Biotechnology, 2022 Perennial plant breeding is an expensive and time-consuming process, mainly due to the extended growth time for juveniles. In these cases, the use of molecular marker-assisted selection (MMAS) allows for the selectionof a characteristic of interest at ...
Bruno Rafael Alves Rodrigues +3 more
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