Results 121 to 130 of about 427,345 (355)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Whole Genome Sequencing of Elite Rice Cultivars as a Comprehensive Information Resource for Marker Assisted Selection

PLoS ONE, 2015
Current advances in sequencing technologies and bioinformatics revealed the genomic background of rice, a staple food for the poor people, and provided the basis to develop large genomic variation databases for thousands of cultivars.
J. Duitama, Alexander Silva, Y. Sanabria, D. Cruz, C. Quintero, C. Ballen, M. Lorieux, B. Scheffler, A. Farmer, Edgar A. Torres, J. Oard, J. Tohme   +11 more
semanticscholar   +1 more source

Economic Analysis of Marker-Assisted Selection in Canola [PDF]

Replaced with revised version of poster 07/19/11.Production Economics, Productivity Analysis, Research and Development/Tech Change/Emerging Technologies,
Naseem, Anwar, Singla, Rohit
core   +1 more source

Improving stress coping ability: comparison between the CYP17 genotype Of Ovis Aries and Capra Hircus [PDF]

, 2010
The ability of animals to adapt to stress is not only an animal health and welfare concern, but also influences reproduction potential and robustness. An important pathway involved in the stress response is the hypothalamic-pituitary-adrenal axis (HPAA ...
Cloete, S.W.P., Hough, D., Storbeck, K., Swart, P.   +3 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Application of whole genome re-sequencing data in the development of diagnostic DNA markers tightly linked to a disease-resistance locus for marker-assisted selection in lupin (Lupinus angustifolius)

BMC Genomics, 2015
Molecular marker-assisted breeding provides an efficient tool to develop improved crop varieties. A major challenge for the broad application of markers in marker-assisted selection is that the marker phenotypes must match plant phenotypes in a wide ...
Huaan Yang, Jianbo Jian, Xuan Li, D. Renshaw, J. Clements, M. Sweetingham, C. Tan, Chengdao Li   +7 more
semanticscholar   +1 more source

Marker-assisted selection for biotic stress (Bacterial leaf blight and gall midge) tolerance in Bc4F4 generation of rice (Oryza sativa L.)

Electronic Journal of Plant Breeding, 2018
Bacterial blight (BB) of rice caused by the pathogen Xanthomonas oryzae pv. oryzae and the insect gall midge (GM) (Orseolia oryzae) are two major limitations of rice production.
Krishnakumar R and, N. Kumaravadivel
doaj   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Identification of QTLs for Rust Resistance in the Peanut Wild Species Arachis magna and the Development of KASP Markers for Marker-Assisted Selection

G3: Genes, Genomes, Genetics, 2015
Rust is a major pathogen of the peanut crop. Development and adoption of rust-resistant cultivars is the most cost efficient and effective way to control the spread of the disease and reduce yield losses.
S. Leal‐Bertioli, Uiara Cavalcante, Ediene G. Gouvea, C. Ballén‐Taborda, K. Shirasawa, P. Guimaraes, S. Jackson, D. Bertioli, M. Moretzsohn   +8 more
semanticscholar   +1 more source

Knowledge database assisted gene marker selection for chronic lymphocytic leukemia

Journal of International Medical Research, 2018
Objective To investigate whether previously curated chronic lymphocytic leukemia (CLL) risk genes could be leveraged in gene marker selection for the diagnosis and prediction of CLL.
Xixi Xiang, Yu-Ping Wang, Hongbao Cao, Xi Zhang   +3 more
doaj   +1 more source