Results 161 to 170 of about 78,970 (275)

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens, Paula Terroba‐Navajas, Eline A.J. Willemse, Sabine Schädelin, Manuel Comabella, Christian Münz, Gordan Lauc, Yannic Bartsch, Jens Kuhle, Jan D. Lünemann   +9 more
wiley   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Molecular and phenotypic characterization of SG9R-like <i>Salmonella</i> Gallinarum field isolates from South Korea, 2019-2025. [PDF]

Front Vet Sci
Lai VD, Nguyen HM, Baek H, Mo J.
europepmc   +1 more source

Comparison of Receptor‐Mediated Endocytosis and Its Application to Enhance DNA Transfection by TFAMoplex

Advanced NanoBiomed Research, EarlyView.
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer, Steffen Honrath, Jonas Kurmann, Alexander Klipp, Finn Brigger, Jean‐Christophe Leroux   +5 more
wiley   +1 more source

Immunogenicity of an Inactivated DIVA Lumpy Skin Disease Virus Vaccine in Guinea Pigs and Lactating Cows, and Its Effects on Cow Lactation. [PDF]

Vaccines (Basel)
Testa L, Capista S, Serroni A, Iorio M, Ronchi GF, Traini S, Matteo ID, Laguardia C, Profeta F, Palucci C, Caporale M, Saletti MA, Marchegiano A, Pinoni C, Rossi E, Salini R, Aretusi G, Armillotta G, Fanì S, Parolini F, Ventura MD, Mercante MT.   +21 more
europepmc   +1 more source

Immune response to rotavirus vaccines in low- and middle-income countries: Challenges and perspectives. [PDF]

Hum Vaccin Immunother
Morandi E, Della Peruta M, Mancini F, Rossi O, Loomis RJ, Iturriza-Gómara M.   +5 more
europepmc   +1 more source

Outcomes of an Alpha-DC-1 Dendritic Cell-Based Vaccine Clinical Trial in Patients with Low-Tumor-Burden High-Risk Ovarian Carcinoma. [PDF]

Cancers (Basel)
Stiff PJ, Czerlanis CM, Potkul RK, Liotta M, Yu Z, Pease L, Banerjee S, Mehrotra S, Winder A, Guevara J, Palmer D, Drakes ML.   +11 more
europepmc   +1 more source

Searching for immune correlates in Lassa vaccine development - workshop report. [PDF]

NPJ Vaccines
Brasel T, Brangel P, Adetifa I, Baize S, Benkeser D, Bertoletti A, Bukreyev A, Charlton S, Cramer J, Cross RW, Davenport MP, Emperador D, Formenty P, Follmann D, Garry RF, Gilbert PB, Gilbert SC, Gollihar JD, Grassly NC, Gruber M, Gupta SB, Günther S, Hacker A, Hoath C, Holbrook MR, Killip M, King D, Mandi H, Munster VJ, Mukandavire C, Oestereich L, Okogbenin S, Oloo P, Paessler S, Plotkin S, Richert L, Safronetz D, Saphire EO, Sette A, Shurtleff A, Granerod J, Wohl D, Zaric M, Ramsauer K, Dahlke C.   +44 more
europepmc   +1 more source

PEG Alternatives in Liposomal Nanocarriers: Physicochemical Characteristics and Sustainable Process Strategies

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The global trend toward sustainable and intensified bioprocesses is driving innovation in the design and scalable synthesis of liposomal nanocarriers, a cornerstone of modern drug delivery. For decades, these nanosystems have relied exclusively on polyethylene glycol (PEG) for their sustained circulation in vivo, but they are currently ...
Chandra Has
wiley   +1 more source