Results 51 to 60 of about 864,749 (292)

The development of contraceptive vaccines [PDF]

, 2002
The use of vaccination as a means of controlling fertility was established during the last decade with the publication of a successful Phase II trial demonstrating the efficacy of this approach to family planning.
Delves, PJ
core  

Digital exhibitions: engaging in public scholarship with primary source materials

, 2019
This article was published as Marker, Rhonda J., "Digital Exhibitions: Engaging in Public Scholarship with Primary Source Materials" in Quick Hits: Teaching with the Digital Humanities, edited by Michael Morrone, Christopher Young, Emma Wilson and Tom ...

core   +1 more source

Charge‐Reversed Lipid Nanoparticles Enable Encapsulation of Pt2L4 Nanocages for In vivo Anti‐Cancer Treatment

Advanced Materials, EarlyView.
Charge‐reversed lipid nanoparticles (revLNPs) enable efficient encapsulation and delivery of cationic Pt2L4 nanocages. Encapsulation preserves potent anticancer activity while improving circulation, reducing vascular leakage, and promoting favorable biodistribution in vivo.
Renzo A. Knol, Bochuan Hu, Eduard O. Bobylev, Martina Farber, Petrus C. M. Laan, Thomas J. F. Kock, Bauke Fontein, Johanna Erbani, Oscar Escalona‐Rayo, Seline S. Roose, Tom Keijer, Gabriel Forn‐Cuní, B. Ewa Snaar‐Jagalska, Leila Akkari, Joost N. H. Reek, Alexander Kros, Dennis Aschmann   +16 more
wiley   +1 more source

Aujeszky’s Disease and the Development of the Marker/DIVA Vaccination Concept [PDF]

Pathogens, 2020
Aujeszky’s disease or pseudorabies is an infection of animals caused by Suid alphaherpesvirus 1, also designated as pseudorabies virus (PrV). Whereas many mammals are susceptible to PrV, only pigs are able to survive productive infection. Early reports on this disease originate from cattle and companion animals with the hallmark sign of “mad itch ...
openaire   +3 more sources

A population genetics model of marker-assisted selection [PDF]

, 1997
A deterministic two-loci model was developed to predict genetic response to marker-assisted selection (MAS) in one generation and in multiple generations.
Luo, Z. W., Woolliams, J. A., Luo, Z.W., Woolliams, John, Thompson, R.   +4 more
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The Seroepidemiology of Haemophilus influenzae Type B Prior to Introduction of an Immunization Programme in Kathmandu, Nepal. [PDF]

, 2014
Haemophilus influenzae type b (Hib) is now recognized as an important pathogen in Asia. To evaluate disease susceptibility, and as a marker of Hib transmission before routine immunization was introduced in Kathmandu, 71 participants aged 7 months-77 ...
Neelam Adhikari, Thorson, SM, Clutterbuck, EA, Marshall, AS, Gautam Samir C., Adhikari, N, Shrestha, S, Barker, CI, Andrew J. Pollard (44971), Shrestha Shrijana, Barker Charlotte I. S., Pollard Andrew J., Kelly Dominic F., Elizabeth A Clutterbuck, Dominic F. Kelly (301751), Samir C Gautam, Adhikari Neelam, Charlotte I S Barker, Clutterbuck Elizabeth A., Pulickal Anoop S., Shrijana Shrestha, Kibwana, E, Dominic F Kelly, Andrew J Pollard, Marshall Andrew S. J., Pulickal, AS, Gautam, SC, Andrew S J Marshall, Anoop S. Pulickal (512430), Anoop S Pulickal, Thorson Stephen M., Charlotte I. S. Barker (512429), Samir C. Gautam (301746), Kibwana Elizabeth, Stephen M Thorson, Elizabeth Kibwana (512431), Kelly, DF, Stephen M. Thorson (512433), Pollard, AJ, Neelam Adhikari (301753), Pollard, Andrew, Elizabeth Kibwana, Andrew S. J. Marshall (512428), Shrijana Shrestha (512434), Elizabeth A. Clutterbuck (512432)   +44 more
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Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang, Xuan Wang, Xinfeng Dai, Linxin Tian, Wencheng Shen, Xueliang Liu, Wei Xue, Jiahua Pan, Yu Yang   +8 more
wiley   +1 more source

The use of green fluorescent protein as a marker for Brucella vaccines [PDF]

Vaccine, 2011
Brucellosis is an important malady of productive and wildlife animals and a worldwide zoonosis. The use of effective vaccines and the corresponding diagnostic tests that allow differentiating infected from vaccinated animals are essential tools to control the disease.
Chacón-Díaz, Carlos, Muñoz, Melissa, BARQUERO-CALVO, ELIAS, Guzman-Verri, Caterina, Chaves-Olarte, Esteban, Grilló, María-Jesús, Moreno, Edgardo   +6 more
openaire   +5 more sources

A simplified protocol for detecting two systemic bait markers (Rhodamine B and iophenoxic acid) in small mammals [PDF]

, 2003
We developed a method of quantifying levels of fluorescence in the whiskers of wild stoats (Mustela erminea) using fluorescence microscopy and Axiovision 3.0.6.1 software. The method allows for discrimination between natural fluorescence present in or on
King, Carolyn M., Petcu, M., M. Petcu, Purdey, D. C., D. C. Purdey, C. M. King   +5 more
core   +1 more source

Nanoparticles and Antiviral Vaccines

, 2023
Viruses have threatened human lives for decades, causing both chronic and acute infections accompanied by mild to severe symptoms. During the long journey of confrontation, humans have developed intricate immune systems to combat viral infections.
Xingyu Liu, Tao Chen, Xiancai Ma, Meilin Hu, Shiqi Xiao, Yiqiang Zhu, Taizhen Liang, Sen Liu, Xiaoqing Liu, Peiwen Li   +9 more
core   +1 more source