Results 91 to 100 of about 3,293,514 (315)

Free DNA in Urine: A New Marker for Bladder Cancer? Preliminary Data

The International Journal of Biological Markers, 2005
The aim of the present preliminary study was to investigate the presence of free DNA (FDNA) in urine as a possible marker for the diagnosis of bladder cancer. Naturally voided morning urine specimens were collected from 57 patients with suspected bladder
M. Zancan, R. Franceschini, C. Mimmo, M. Vianello, F. Di Tonno, C. Mazzariol, G. Malossini, M. Gion   +7 more
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

A novel approach for mining polymorphic microsatellite markers in silico [PDF]

, 2011
Hoffman J, Nichols HJ. A novel approach for mining polymorphic microsatellite markers in silico. PLoS ONE. 2011;6(8): e23283.Abstract: An important emerging application of high-throughput 454 sequencing is the isolation of molecular markers such as ...
Joseph I. Hoffman, Hoffman, Joseph ; https://orcid.org/, Hazel Nichols, Nichols, H. J., Nichols Hazel J., Hazel J. Nichols, Joseph I Hoffman, Hazel J Nichols, Hoffman Joseph I.   +8 more
core   +2 more sources

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Development of Sequence Tagged Microsatellite Site (STMS) markers in Azalea [PDF]

, 2001
A genomic library was constructed from DNA of two azalea genotypes: a Belgian pot azalea R. simsii hybrid Mevr. Van Belle and a Chinese R. simsii from Daoxian.
Arens, P., Bockstaele, E., van, Loose, M., de, Riek, J., de, Dendauw, J., Vosman, B.   +5 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Impact of Steroid Receptors, pS2 and Cathepsin D on the Outcome of N+ Postmenopausal Breast Cancer Patients Treated with Tamoxifen

The International Journal of Biological Markers, 1998
In spite of the complexity of the biological basis of the hormonal regulation of breast cancer, clinical studies tend to simplify the information by mainly categorizing continuous variables related to hormonal status and not considering the interactions ...
R. Dittadi, E. Biganzoli, P. Boracchi, C. Salbe, R. Mione, C. Gatti, M. Gion   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Development and non-clinical characterization of Procizumab (invobenitug): a humanized antibody neutralizing circulating DPP3

mAbs
Dipeptidyl peptidase 3 (DPP3) is an intracellular protein involved in cellular antioxidant responses. Upon acute stress and tissue damage, DPP3 is released into the circulation (circulating DPP3, cDPP3), where it induces vascular, cardiac, and immune ...
Magali Genest, Dirk Van Lier, Theo Ikenna Uba, Anika Schroeter, Adrien Picod, Hugo Nordin, Noma Assad, Gwendolyn Marguerit, Alexis Nguyen, Andreas Bergmann, Peter Pickkers, Alexandre Mebazaa, Karine Santos, Feriel Azibani   +13 more
doaj   +1 more source

Today’s oxidative stress markers [PDF]

, 2015
Oxidative stress represents a situation where there is an imbalance between the reactive oxygen species (ROS) and the availability and the activity of antioxidants.
Marta Czerska, Marek Zieliński, Mikołajewska, Karolina, Wojciech Wąsowicz, Karolina Mikołajewska, Jolanta Gromadzińska, Zieliński, Marek, Wąsowicz, Wojciech, Gromadzińska, Jolanta, Czerska, Marta   +9 more
core   +2 more sources