Results 81 to 90 of about 3,384,589 (315)

Neurogranin and tau in cerebrospinal fluid and plasma of patients with acute ischemic stroke

BMC Neurology, 2017
Background While neurogranin has no value as plasma biomarker for Alzheimer’s disease, it may be a potential blood biomarker for traumatic brain injury. This evokes the question whether there are changes in neurogranin levels in blood in other conditions
Ann De Vos, Maria Bjerke, Raf Brouns, Naomi De Roeck, Dirk Jacobs, Lien Van den Abbeele, Kaat Guldolf, Henrik Zetterberg, Kaj Blennow, Sebastiaan Engelborghs, Eugeen Vanmechelen   +10 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Standardization and application of microsatellite markers for variety identification in tomato and wheat [PDF]

, 2001
The present study is part of a EU project that aims to demonstrate the technical viability of STMS markers for variety identification. As examples two important European crop species, tomato and wheat were chosen. Initially, about 30-40 STMS markers were
Ganal, M., Peeters, R., Cooke, R., Bredemeijer, G., Vosman, B., Isaac, P.   +5 more
core   +1 more source

2 Discourse markers vs other types of pragmatic markers

This chapter proposes a principled distinction between discourse markers, cohesive devices that stress intra-discourse relations, and pragmatic markers, functional items that have interactional and (inter)subjective meanings. Well aware of the challenge
Molinelli, Piera
core   +2 more sources

Free DNA in Urine: A New Marker for Bladder Cancer? Preliminary Data

The International Journal of Biological Markers, 2005
The aim of the present preliminary study was to investigate the presence of free DNA (FDNA) in urine as a possible marker for the diagnosis of bladder cancer. Naturally voided morning urine specimens were collected from 57 patients with suspected bladder
M. Zancan, R. Franceschini, C. Mimmo, M. Vianello, F. Di Tonno, C. Mazzariol, G. Malossini, M. Gion   +7 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

D-dimer and international normalized ratio (INR) are correlated with tumor markers and disease stage in colorectal cancer patients.

, 2015
BACKGROUND: The aim of this study is to evaluate the correlation of coagulation tests with various clinicopathological variables and tumor markers among colorectal cancer (CRC ...
ERDEM, Mustafa Genco, Tas, Faruk, Serilmez, Murat, Yildiz, Ibrahim, Sen, Fatma Karagoz, Karabulut, Senem, Duranyildiz, Derya, Ciftci, Rumeysa, ORDU, Cetin, Keskin, Serkan, Kilic, Leyla   +10 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source