Results 21 to 30 of about 6,228,391 (354)

Evaluating predictive pharmacogenetic signatures of adverse events in colorectal cancer patients treated with fluoropyrimidines [PDF]

, 2013
The potential clinical utility of genetic markers associated with response to fluoropyrimidine treatment in colorectal cancer patients remains controversial despite extensive study.
A Fariña-Sarasqueta, A Loganayagam, A Ruzzo, A Ruzzo, A Yawata, A Zaniboni, Andreas-Claudius Hoffmann, Ann Barrett, B Glimelius, BA Jennings, Barbara A. Jennings, C Fernandez-Rozadilla, C Zhang, CE de Bock, CF Thorn, D Caronia, Daniel Epurescu, DB Longley, E Hitre, E Van Cutsem, G Willis, Gavin S. Chu, Gavin Willis, H Gellekink, H Taflin, I Weisberg, J Cassidy, Jane Skinner, K Derwinger, K Kawakami, K Kawakami, L Peter, L Sharp, M Boisdron-Celle, M Gusella, M Scartozzi, M Schwab, M Vignoli, ME Fernández-Contreras, Melanie Keane, MJ Deenen, MS Braun, MV Mandola, MV Mandola, MV Mandola, N Horie, P Frosst, R Pullmann Jr., RA Goodwin, Richard Turner, S Afzal, S Afzal, S Kaneda, T André, TV Perneger, V Sulzyc-Bielicka, W Ichikawa, W Scheithauer, WG Johnson, Yoon K. Loke   +59 more
core   +15 more sources

Overview of General and Discriminating Markers of Differential Microglia Phenotypes

Frontiers in Cellular Neuroscience, 2020
Inflammatory processes and microglia activation accompany most of the pathophysiological diseases in the central nervous system. It is proven that glial pathology precedes and even drives the development of multiple neurodegenerative conditions.
A. Jurga, Martyna Paleczna, K. Kuter
semanticscholar   +1 more source

Rapid SNP Discovery and Genetic Mapping Using Sequenced RAD Markers

PLoS ONE, 2008
Single nucleotide polymorphism (SNP) discovery and genotyping are essential to genetic mapping. There remains a need for a simple, inexpensive platform that allows high-density SNP discovery and genotyping in large populations.
N. Baird, Paul D. Etter, T. S. Atwood, M. Currey, A. Shiver, Zachary A. Lewis, E. Selker, W. Cresko, Eric A. Johnson   +8 more
semanticscholar   +1 more source

Clinical Utility of Prostatic Specific Antigen and Prostatic Acid Phosphatase Serum Levels in Monitoring Prostate Cancer

The International Journal of Biological Markers, 1988
We analysed 696 prostatic specific antigen (PSA) and prostatic acid phosphatase (PAP) serum samples by double antibody radioimmunoassay (RIA) I 125 in the follow-up of 122 patients with prostate cancer under treatment.
J. Morote, A. Ruibal, J. Palou, J. A. de Torres, A. Soler-Roselló   +4 more
doaj   +1 more source

Conjugated Polymeric Materials in Biological Imaging and Cancer Therapy

Molecules, 2023
Conjugated polymers (CPs) have attracted much attention in the fields of chemistry, medicine, life science, and material science. Researchers have carried out a series of innovative researches and have made significant research progress regarding the ...
Qinbin Zheng, Zhuli Duan, Ying Zhang, Xinqi Huang, Xuefan Xiong, Ang Zhang, Kaiwen Chang, Qiong Li   +7 more
doaj   +1 more source

Aptamer Functionalized Upconversion Nanotheranostic Agent With Nuclear Targeting as the Highly Localized Drug-Delivery System of Doxorubicin

Frontiers in Bioengineering and Biotechnology, 2021
As a widely used anticancer drug, doxorubicin (DOX) could induce cell death mainly via interfering with DNA activity; thus, DOX could perform therapeutic effects mainly in the cell nucleus.
Xinyue Song, Xinyue Song, Tao Yan, Feng Tian, Fengyan Li, Linlin Ren, Qiong Li, Qiong Li, Shusheng Zhang   +8 more
doaj   +1 more source

Lack of correlation of stem cell markers in breast cancer stem cells [PDF]

, 2014
BACKGROUND: Various markers are used to identify the unique sub-population of breast cancer cells with stem cell properties. Whether these markers are expressed in all breast cancers, identify the same population of cells, or equate to therapeutic ...
A M Thompson, AM Thompson, C Calabrese, C Ginestier, C Scheel, C Sheridan, CE Eyler, CL Chaffer, CM Fillmore, E Charafe-Jauffret, E Resetkova, EY Tan, F Vaillant, G Farnie, G Kristiansen, G Rappa, H Harrison, H Korkaya, J Stingl, J Zhou, JC Lawson, JM Rosen, K Engelmann, K He, K Murray, M Al-Hajj, M Boylan, M Christgen, M Kok, M Pajic, M V Appleyard, MA Ahmed, ME Prince, MH Wright, MJ Grimshaw, MV Appleyard, O Al-Assar, O Leis, O Moussa, P J Coates, P Kabos, R Nenutil, S Bao, S Liu, SY Kim, SY Park, T Tanei, TM Phillips, WW Hwang-Verslues, Y Liu   +49 more
core   +4 more sources

FerrDb: a manually curated resource for regulators and markers of ferroptosis and ferroptosis-disease associations

Database J. Biol. Databases Curation, 2020
Ferroptosis is a mode of regulated cell death that depends on iron. Cells die from the toxic accumulation of lipid reactive oxygen species. Ferroptosis is tightly linked to a variety of human diseases, such as cancers and degenerative diseases.
N. Zhou, J. Bao
semanticscholar   +1 more source

Detection of Tobacco Bacterial Wilt Caused by Ralstonia solanacearum by Combining Polymerase Chain Reaction with an α-Hemolysin Nanopore

Nanomaterials, 2023
Tobacco bacterial wilt is a serious disease caused by the soil-borne bacterium Ralstonia solanacearum (R. solanacearum). Herein, a rapid and purification-free α-hemolysin (α-HL) nanopore-sensing strategy based on polymerase chain reaction (PCR) and ...
Ying Wang, Yusen Li, Xin Zhou, Wenna Zhang, Shusheng Zhang, Dongmei Xi   +5 more
doaj   +1 more source

Genetic diversity of peanut (Arachis hypogaea L.) and its wild relatives based on the analysis of hypervariable regions of the genome [PDF]

, 2004
BACKGROUND: The genus Arachis is native to a region that includes Central Brazil and neighboring countries. Little is known about the genetic variability of the Brazilian cultivated peanut (Arachis hypogaea, genome AABB) germplasm collection at the DNA ...
Ferreira, Marcio Elias, Hopkins, Mark S, Kresovich, Stephen, Mitchell, Sharon E, Moretzsohn, Marcio de Carvalho, Valls, Jose Francisco Montenegro   +5 more
core   +4 more sources