Results 191 to 200 of about 51,005,658 (304)

Identifying a Csmd3+ Microglial Subpopulation that Drives Cold‐to‐Hot Transition and Immune‐Cure in Glioblastoma

Advanced Science, EarlyView.
The study establishes an immune‐cure (ICu) mouse model based on a TMEMed G422TN‐GBM system that faithfully recapitulates human TMEMed GBM. scRNA‐seq analysis reveals a Csmd3+ microglial subset with innate immune memory (IIM) potential that potently suppresses GBM growth, drives a TME cold‐to‐hot transition, and induces 100% ICu in long‐term survival ...
Hai‐Feng Jiang, Pan‐Pan Gao, Yu‐Wen Du, Li‐Qin Wu, En‐Zhi Yin, Qi An, Ze‐Hua Ding, Jin‐Wen Shi, Ya Shu, Ruoqiao Chen, Feng Liu, Mingfeng Li, Xiao Qian Chen   +12 more
wiley   +1 more source

Post-Marketing Requirements for Anticancer Drugs Approved in Japan, 2001-2024: A Cross-Sectional Analysis. [PDF]

CPT Pharmacometrics Syst Pharmacol
Tsuno A, Kitagaki H, Maeda H.
europepmc   +1 more source

MgP4/CNT‐Graphene Embedded in Hard Carbon Matrix as a High‐Capacity Anode for Next‐Generation Sodium‐Ion Batteries

Advanced Science, EarlyView.
Phosphorus‐rich MgP4 is introduced as a high capacity anode for sodium‐ion batteries (SIBs) via hybrid carbon matrix engineering. A sequential CNT/G assembly forms a conductive and mechanically robust network, delivering a high reversible capacity of 1386 mAh g−1 while stabilizing alloying reactions.
Sion Ha, Doyeon Lee, Dong Won Kim, Won‐Sik Kim, Minkyu Lee, Seong‐Hyeon Hong, Kyeong‐Ho Kim   +6 more
wiley   +1 more source

Mitigating the burden of dental caries among adolescents and young adults by targeting social media influencers. [PDF]

Front Oral Health
Shrivastava SR, Bobhate PS, Mendhe HG, Petkar PB.   +3 more
europepmc   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source

Social Media as a Driver of Obesity in Children and Adolescents (Aged 6-18 Years): It Is Time for Regulatory Action. [PDF]

J Med Internet Res
Liu Y, Li W, Wen LM, He G.
europepmc   +1 more source

In Situ Alkali Metal Exfoliation‐Coupled Dilute CO2 Electrolysis to Synthesize Interlayer‐Expanded Graphite for High‐Rate Lithium Storage

Advanced Science, EarlyView.
Converting CO2 into advanced carbon materials capable of meeting the rapid lithium storage demands of lithium‐ion batteries creates a mutually beneficial scenario for both energy and environmental sectors. Here, we propose a stepwise CO2 electrolysis approach to transform dilute CO2 into interlayer‐expanded graphite using molten salt electrolyzers ...
Hao Zha, Xiaodan Zhang, Xinyu Li, Jiajun Li, Yuxin Wu, Xiaoyang Wang, Huayi Yin, Dihua Wang, Bowen Deng   +8 more
wiley   +1 more source

Marketing a Plastic Surgery Practice: Strategies, Insights, and Practical Considerations. [PDF]

Plast Reconstr Surg Glob Open
Khosla AS, Zeitouni F, Laning EK, Tierney M, Attaluri PK, Rao VK.   +5 more
europepmc   +1 more source

EDNRA Forms a Positive Feedback Loop with the Hippo/YAP Axis to Drive Triple‐Negative Breast Cancer Progression

Advanced Science, EarlyView.
Endothelin receptor type A (EDNRA) and the Hippo/YAP pathway form a self‐reinforcing loop that sustains triple‐negative breast cancer. EDNRA activates YAP through Gαq/11–Rho/ROCK–LATS signaling, while YAP/TEAD4 reciprocally drives EDNRA transcription.
Zehao Hong, Boyang Li, Jiahui Xu, Ruonan Lin, Jinghao Pan, Chenlu Fang, Boxiang Zhang, Lucy Yue Lau, Richard J. Aldridge, Elizabeth A. Whitmore, Yi Chen   +10 more
wiley   +1 more source

Recruitment strategies in the PROMISE Registry: Evaluating institutional outreach, direct-to-patient marketing, and community engagement approaches in a decentralized germline genetic registry. [PDF]

Contemp Clin Trials Commun
Paller CJ, Freitas K, Macario N, Tran C, Faville K, Wiedemer K, Chiang J, Lorentz J, Appleman LJ, Armstrong AJ, Barata PC, Borno HT, Crawford K, DeMarco TA, Dreicer R, Elrod JAB, Gabram S, George C, Heath EI, Hussain A, Hussain MHA, Neil JM, Mao S, McKay RR, Morgans AK, Ogunsanya ME, Orton M, Ritchie T, Saraiya B, Sokolova AO, Szmulewitz R, Fortt I, Ramos L, Smith S, Freeman P, McMannis A, Green R, Vinson J, Cheng HH.   +38 more
europepmc   +1 more source