Results 241 to 250 of about 348,965 (301)

The immune landscape of uterine fibroids as determined by mass cytometry. [PDF]

F S Sci
Boos D, Chuang TD, Abbasi A, Luzzi A, Khorram O.   +4 more
europepmc   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Multiplexed imaging mass cytometry elicits p-S6 as a therapeutic and prognostic factor in diffuse large B-cell lymphoma. [PDF]

Blood Adv
Zhang B, Xie Y, Shen M, Sun J, Li Y, Zhang J, Li Q, Chen C, Chen Z, Wang W, Wu J, Zhou Z, Fang J, Yan Y, Qian S, Tong X, Lin N, Tong H.   +17 more
europepmc   +1 more source

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Zhang B, Xie Y, Shen M, et al. Multiplexed imaging mass cytometry elicits p-S6 as a therapeutic and prognostic factor in diffuse large B-cell lymphoma. Blood Adv. 2025;9(13):3249-3262. [PDF]

Blood Adv
europepmc   +1 more source

Engineered Carbon Dots from a Traditional Herb Pair Orchestrate Concurrent Antioxidant and AP‐1‐Mediated Inflammation to Attenuate Renal Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study integrates two complementary traditional Chinese medicine components as precursors to synthesize bioactive AM‐AS@CDs. Compared with single‐component CDs, these dual‐component CDs exhibit enhanced antioxidant capacity and superior renoprotective effects.
Bixiao Liu, Fuying Zhu, Zhuqing Wang, Jiawen Chen, Xiaomiao Cui, Congzhong Yang, Yao Peng, Dengyuan Feng, Li Lu, Hui Wei, Xiaozhi Zhao   +10 more
wiley   +1 more source

Multiplexed Imaging Mass Cytometry Reveals Tumor-immune Microenvironment-dependent Hormone Receptor Expression in Adult-Type Ovarian Granulosa Cell Tumors. [PDF]

Cancer Res Commun
Khlebus EY, Vuttaradhi VK, Ferri-Borgogno S, Brodsky AL, Lawson BC, Mok SC, Hillman RT.   +6 more
europepmc   +1 more source

IL-6R blockade combined with immunosuppressants alleviates adult-onset Still's disease through immune remodeling: a mass cytometry study. [PDF]

J Transl Med
Guo R, Zhang T, Li Y, Liu X, Meng X, Tong L, Chen X, Ding X, Lu L.   +8 more
europepmc   +1 more source

Mass cytometry analysis reveals a cross-tissue immune landscape in <i>Actinobacillus pleuropneumoniae</i>-induced pneumonia. [PDF]

Microbiol Spectr
Tian Y, Jiang X, Bao C, Abdelaal T, Chen D, Wang W, Li F, Lei L, Li N.   +8 more
europepmc   +1 more source

Mass cytometry: exploring the immune landscape of systemic autoimmune and inflammatory diseases in the past fourteen years. [PDF]

Front Immunol
Kante A, Chevalier MF, Sène D, Chauffier J, Mouly S, Chousterman BG, Azibani F, Terrier B, Pezel T, Comarmond C.   +9 more
europepmc   +1 more source