Results 201 to 210 of about 687,738 (249)

Nanobody‐Conjugated Theranostic Prodrug Targeting αvβ3 Integrin Enables Precision Cancer Therapy With Real‐Time Imaging

Advanced Healthcare Materials, EarlyView.
The image shows a schematic form a nanobody‐conjugated theranostic prodrug (NBD) platform targeting tumor‐associated αvβ3 integrin. The NBD system integrates selective nanobody‐mediated tumor recognition, glutathione‐responsive disulfide cleavage for doxorubicin release, and aza‐BODIPY‐based near‐infrared fluorescence for real‐time imaging.
Sanu Karan, Hyunseung Lee, Rema Naskar, Mi Young Cho, Hye Sun Park, Eun Hee Han, Soumyadip Hore, Sun Hee Cho, Truc Ngoc Kim Lam, Taewoong Son, Tae Jung Park, Inkyu Hwang, Jonathan L. Sessler, Kwan Soo Hong   +13 more
wiley   +1 more source

Integrating social and behavior change communication into mass drug administration campaigns for neglected tropical diseases: insights and best practices from Jimma, Ethiopia. [PDF]

Front Public Health
Birhanu Z, Sudhakar M, Abdissa D, Abraham G, Bulcha G, Shiferaw T, Berhanu N, Teshome F, Miecha H, Kebede Y.   +9 more
europepmc   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Microplanning improves stakeholders' perceived capacity and engagement to implement lymphatic filariasis mass drug administration. [PDF]

PLoS Negl Trop Dis
Worrell CM, Brant TA, Javel A, Denis E, Fayette C, Monestime F, Knowles E, Bennett C, Utzinger J, Odermatt P, Lemoine JF.   +10 more
europepmc   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Cross-sectional epidemiological assessment of lymphatic filariasis situation in areas under post-mass drug administration surveillance and the associated risk of transmission in the context of migrants in India: a study protocol. [PDF]

BMJ Open
Srividya A, Dinesh RJ, M M MJ, Kishanthini M, Dogra V, Tripathi B, Sharma R, Jain T, Rahi M.   +8 more
europepmc   +1 more source

Identifying hotspots of S. haematobium infection following praziquantel treatment during multiple annual mass drug administration campaigns in Zimbabwe. [PDF]

PLoS Negl Trop Dis
Mduluza T, Zdesenko G, Tagwireyi P, Jones CM, Mutapi F.   +4 more
europepmc   +1 more source

Determinants of acceptability of schistosomiasis mass drug administration among primary school children in Busega District, Northwestern Tanzania. [PDF]

PLoS One
Edward IY, Maritim P, Jacobs C, Silumbwe A, Mohamed H, Zulu JM, Halwiindi H.   +6 more
europepmc   +1 more source

Healthcare Undergraduates' Perception and Practice Regarding Lymphatic Filariasis and Mass Drug Administration in a Tertiary Care Facility in Eastern India. [PDF]

Cureus
Biswas B, Pathak HN, Gupta P, Jahnavi G, Kalyani CV, Varshney S.   +5 more
europepmc   +1 more source