Results 111 to 120 of about 3,177,228 (297)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Analysis of Strength Degradation of Q235 Corroded Steel Based on Pitting Evolution

Taiyuan Ligong Daxue xuebao
Proposes To evaluate the strength degradation behavior of corroded steel with pitting evolution, an in-situ pitting evolution method is achieved by ABAQUS software combined with Python program according to pit statistics on steel matrix surfaces at ...
Benzhao FU, Ruizong LIN, Yun ZHAO, QI GUO, Zeyan WU   +4 more
doaj   +1 more source

Neglecting the porosity of hot-star winds can lead to underestimating mass-loss rates

, 2007
Context: The mass-loss rate is a key parameter of massive stars. Adequate stellar atmosphere models are required for spectral analyses and mass-loss determinations.
Feldmeier, A., Hamann, W. -R., Oskinova, L. M.   +2 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Dust Production and Mass Loss in the Galactic Globular Cluster NGC 362

, 2009
We investigate dust production and stellar mass loss in the Galactic globular cluster NGC 362. Due to its close proximity to the Small Magellanic Cloud (SMC), NGC 362 was imaged with the IRAC and MIPS cameras onboard the Spitzer Space Telescope as part ...
Barbara Whitney, Barmby, Bellazzini, Bernie Shiao, Blum, Bolatto, Boyer, Boyer, Boyer, Brian Babler, Catelan, Charles Engelbracht, Clement, Dale, Epchtein, Freire, Gnedin, Gustafsson, Hanner, Harris, Harris, Iain McDonald, Ita, Jacco Th. van Loon, Joana M. Oliveira, Joe Hora, Jäger, Karl D. Gordon, Karl Misselt, Lebzelter, Margaret Meixner, Marilyn Meade, Marta Sewilo, Martha L. Boyer, Matsunaga, McLaughlin, Meixner, Miwa Block, Murakami, Mészáros, Nenkova, Onaka, Origlia, Origlia, Remy Indebetouw, Sarajedini, Schröder, Skrutskie, Smith, Steve Bracker, Tucholke, Werner, Zacharias, Zaritsky   +53 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Study on Freeze–Thaw Resistance of Cement Concrete with Manufactured Sand Based on BP Neural Network

Buildings
In this study, experiments were conducted on the freeze–thaw performance of manufactured sand cement concrete with different sand ratios and fly ash contents.
Hengyu Wu, Qiju Gao
doaj   +1 more source

Global hot-star wind models for stars from Magellanic Clouds

, 2017
We provide mass-loss rate predictions for O stars from Large and Small Magellanic Clouds. We calculate global (unified, hydrodynamic) model atmospheres of main sequence, giant, and supergiant stars for chemical composition corresponding to Magellanic ...
Krticka, Jiri, Kubat, Jiri
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Ignition probability and fuel consumption of boreal ground vegetation fuels – an experimental study in Finland

Silva Fennica
In boreal forests fires often ignite and spread within the dominant moss and lichen cover of the ground layer vegetation, which thus greatly influences fire hazard.
Henrik Lindberg, Tuomas Aakala, Ilkka Vanha-Majamaa   +2 more
doaj   +1 more source