Results 1 to 10 of about 5,622,516 (403)

Basal ganglia neuropeptides show abnormal processing associated with L-DOPA-induced dyskinesia

open access: yesnpj Parkinson's Disease, 2022
L-DOPA administration is the primary treatment for Parkinson’s disease (PD) but long-term administration is usually accompanied by hyperkinetic side-effects called L-DOPA-induced dyskinesia (LID). Signaling neuropeptides of the basal ganglia are affected
Heather Hulme   +7 more
doaj   +1 more source

Liquid chromatography–tandem mass spectrometry for clinical diagnostics

open access: yesNature Reviews Methods Primers, 2022
Mass spectrometry is a powerful analytical tool used for the analysis of a wide range of substances and matrices; it is increasingly utilized for clinical applications in laboratory medicine.
Stefani N. Thomas   +4 more
semanticscholar   +1 more source

Volatiles Emission by Crotalaria nitens after Insect Attack

open access: yesMolecules, 2021
Plants are known to increase the emission of volatile organic compounds upon the damage of phytophagous insects. However, very little is known about the composition and temporal dynamics of volatiles released by wild plants of the genus Crotalaria ...
Fausto Prada   +2 more
doaj   +1 more source

Advances in mass spectrometry imaging for spatial cancer metabolomics.

open access: yesMass spectrometry reviews (Print), 2022
Mass spectrometry (MS) has become a central technique in cancer research. The ability to analyze various types of biomolecules in complex biological matrices makes it well suited for understanding biochemical alterations associated with disease ...
Xin Ma, Facundo M. Fernández
semanticscholar   +1 more source

High-Resolution Native Mass Spectrometry

open access: yesChemical Reviews, 2021
Native mass spectrometry (MS) involves the analysis and characterization of macromolecules, predominantly intact proteins and protein complexes, whereby as much as possible the native structural features of the analytes are retained.
S. Tamara, M. A. den Boer, A. Heck
semanticscholar   +1 more source

A Novel Truncated DNAzyme Modified Paper Analytical Device for Point-of-Care Test of Copper Ions in Natural Waters

open access: yesChemosensors, 2022
On-site determination of trace copper ions in natural waters is of great significance to environmental monitoring, and how to develop accurate and specific point-of-care test methods is one critical issue.
Jiayi Wu   +5 more
doaj   +1 more source

Bioaerosol Identification by Wide Particle Size Range Single Particle Mass Spectrometry

open access: yesAtmosphere, 2023
The properties of bioaerosols are complex and diverse, and have a direct impact on the environment, climate, and human health. The effective identification of bioaerosols in the atmosphere is very significant with regard to accurately obtaining the ...
Xuan Li   +8 more
doaj   +1 more source

New Development in Ion Mobility Spectrometry for Analysis of Small Molecule Isomers [PDF]

open access: yesZhipu Xuebao, 2022
With the rapid development of modern detection technology and scientific research, the chemical structures and functions of isomers are constantly being revealed.
WU Fang-ling1   +4 more
doaj   +1 more source

The Skyline ecosystem: Informatics for quantitative mass spectrometry proteomics.

open access: yesMass spectrometry reviews (Print), 2020
Skyline is a freely available, open-source Windows client application for accelerating targeted proteomics experimentation, with an emphasis on the proteomics and mass spectrometry community as users and as contributors.
Lindsay K. Pino   +5 more
semanticscholar   +1 more source

Spatially Resolved Mass Spectrometry at the Single Cell: Recent Innovations in Proteomics and Metabolomics

open access: yesJournal of the American Society for Mass Spectrometry, 2021
Biological systems are composed of heterogeneous populations of cells that intercommunicate to form a functional living tissue. Biological function varies greatly across populations of cells, as each single cell has a unique transcriptome, proteome, and ...
Michael J Taylor   +2 more
semanticscholar   +1 more source

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