Results 41 to 50 of about 5,492,223 (387)

Mass Spectrometry and Tandem Mass Spectrometry: An Overview [PDF]

open access: yes, 2014
In this chapter, a brief overview of fundamentals in mass spectrometry and of its applications in homeland security, forensic sciences and explosive detection, are presented.
openaire   +3 more sources

Multiplexed Mass Spectrometry of Individual Ions Improves Measurement of Proteoforms and Their Complexes

open access: yesNature Methods, 2020
An Orbitrap-based ion analysis procedure determines the direct charge for numerous individual protein ions to generate true mass spectra. This individual ion mass spectrometry (I 2 MS) method for charge detection enables the characterization of highly ...
Jared O. Kafader   +15 more
semanticscholar   +1 more source

Development and validation of an LC-MS/MS method for ruxolitinib quantification: advancing personalized therapy in hematologic malignancies

open access: yesJournal of Pharmacy & Pharmaceutical Sciences
BackgroundHematologic malignancies such as leukemia and lymphoma present treatment challenges due to their genetic and molecular heterogeneity. Ruxolitinib, a Janus kinase (JAK) inhibitor, has demonstrated efficacy in managing these cancers.
Na Li   +6 more
doaj   +1 more source

On the chemistry of 1-pyrroline in solution and in the gas phase

open access: yesScientific Reports, 2017
1-Pyrroline has a highly characteristic odor, which is employed by living organisms for chemical signaling and other purposes, but the mechanism whereby this odor is formed remains poorly understood.
Xiaoping Zhang   +5 more
doaj   +1 more source

Mass spectral analysis and quantification of Secondary Ion Mass Spectrometry data

open access: yes, 2014
This work highlights the possibility of improving the quantification aspect of Cs-complex ions in SIMS (Secondary Ion Mass Spectrometry), by combining the intensities of all possible Cs-complexes.
Balamurugan, A. K.   +2 more
core   +1 more source

HIGH RESOLUTION MASS SPECTROMETRY IN LIPIDOMICS

open access: yesMass spectrometry reviews (Print), 2020
The boost of research output in lipidomics during the last decade is tightly linked to improved instrumentation in mass spectrometry. Associated with this trend is the shift from low resolution—toward high‐resolution lipidomics platforms.
Thomas Züllig, H. Köfeler
semanticscholar   +1 more source

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

open access: yesFEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt   +8 more
wiley   +1 more source

Seasonal Variation in Stable Isotope Ratios of Cow Milk in Vilnius Region, Lithuania

open access: yesAnimals, 2019
Various studies have shown that stable isotope analysis has the potential to verify the geographic origin of foods and drinks. However, stable isotope composition is not always constant in the environment and can even change in the same area.
Andrius Garbaras   +4 more
doaj   +1 more source

Tautomeric Equilibria Studies by Mass Spectrometry [PDF]

open access: yes, 2008
Tautomerism in organic chemistry has been extensively studied in condensed phase by spectrometric methods, mainly by IR and NMR techniques. Mass spectrometry studies start 40 years ago but just recently it has been recognized the importance of the mass ...
Eduardo A. Castro   +3 more
core   +1 more source

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