Results 41 to 50 of about 1,192,978 (307)

Application of MALDI-TOF MS Profiling Coupled With Functionalized Magnetic Enrichment for Rapid Identification of Pathogens in a Patient With Open Fracture

Frontiers in Chemistry, 2021
Posttraumatic infections can occur in orthopedic trauma patients, especially in open fractures. Rapid and accurate identification of pathogens in orthopedic trauma is important for clinical diagnosis and antimicrobial treatment.
Jichong Ying, Wenjing Gao, Dichao Huang, Chuanfan Ding, Ling Ling, Tao Pan, Shaoning Yu   +6 more
doaj   +1 more source

Atmospheric Pressure Mass Spectrometry by Single-Mode Nanoelectromechanical Systems [PDF]

arXiv, 2023
Weighing particles above MegaDalton mass range has been a persistent challenge in commercial mass spectrometry. Recently, nanoelectromechanical systems-based mass spectrometry (NEMS-MS) has shown remarkable performance in this mass range, especially with the advance of performing mass spectrometry under entirely atmospheric conditions.
arxiv  

Mass Spectrometry and Tandem Mass Spectrometry: An Overview [PDF]

, 2014
In this chapter, a brief overview of fundamentals in mass spectrometry and of its applications in homeland security, forensic sciences and explosive detection, are presented.
openaire   +3 more sources

Development and validation of an LC-MS/MS method for ruxolitinib quantification: advancing personalized therapy in hematologic malignancies

Journal of Pharmacy & Pharmaceutical Sciences
BackgroundHematologic malignancies such as leukemia and lymphoma present treatment challenges due to their genetic and molecular heterogeneity. Ruxolitinib, a Janus kinase (JAK) inhibitor, has demonstrated efficacy in managing these cancers.
Na Li, Na Li, Huiying Zhang, Huiying Zhang, Haochen Bai, Kaizhi Lu, Kaizhi Lu   +6 more
doaj   +1 more source

Material screening and selection for XENON100 [PDF]

, 2011
Results of the extensive radioactivity screening campaign to identify materials for the construction of XENON100 are reported. This Dark Matter search experiment is operated underground at Laboratori Nazionali del Gran Sasso (LNGS), Italy.
A. Askin, A. Behrens, A. Kish, A. Teymourian, A.C.C. Ribeiro, A.D. Ferella, A.J. Melgarejo Fernandez, Agostinelli, Angle, Aprile, Aprile, Aprile, Arpesella, B. Choi, Baudis, Birkedal-Hansen, Bolozdynya, Bottino, C. Weinheimer, C.W. Lam, Cheng, Clowe, D. Cline, D. Thers, E. Aprile, E. Brown, E. Pantic, E. Tziaferi, Ellis, F. Arneodo, Freedman, G. Plante, Gaitskell, H. Wang, Haffke, Heisel, Heusser, Heusser, Hurtgen, J. Lamblin, J.A.M. Lopes, J.M.F. dos Santos, J.M.R. Cardoso, K. Arisaka, K. Bokeloh, K. Ni, K.E. Lim, K.L. Giboni, Knoll, L. Baudis, M. Laubenstein, M. Schumann, Maneschg, Nisi, Norman, P. Shagin, R. Santorelli, R.F. Lang, S. Fattori, S. Nisi, S.E.A. Orrigo, T. Marrodán Undagoitia, U. Oberlack, Y. Mei, Yamashita   +64 more
core   +3 more sources

Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson’s disease primate model

npj Parkinson's Disease, 2023
Metabolism of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) to the neurotoxin MPP+ in the brain causes permanent Parkinson’s disease-like symptoms by destroying dopaminergic neurons in the pars compacta of the substantia nigra in humans and non ...
Ibrahim Kaya, Anna Nilsson, Dominika Luptáková, Yachao He, Theodosia Vallianatou, Patrik Bjärterot, Per Svenningsson, Erwan Bezard, Per E. Andrén   +8 more
doaj   +1 more source

Isotope ratio - Mass spectrometry [PDF]

, 2012
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32166This article summarizes the configurations involving isotope ratio mass spectrometry (IRMS) technology available at the CCiTUB and the wide range of possible applications. Some examples
Marimon Corbella, Rosa Maria, Perona Moreno, Joaquim, Teixidor Casamitjana, Pilar   +2 more
core   +1 more source

Generic sample preparation combined with high-resolution liquid chromatography- time-of-flight mass spectrometry for unification of urine screening in doping-control laboratories [PDF]

, 2010
A unification of doping-control screening procedures of prohibited small molecule substances—including stimulants, narcotics, steroids, ß2-agonists and diuretics—is highly urgent in order to free resources for new classes such as banned proteins ...
Georgakopoulos, C.G., Nielen, M.W.F., Oosterink, J.E., Peters, R.J.B., Stolker, A.A.M.   +4 more
core   +3 more sources

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

FEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang, Meritxell Wu‐Lu, Alberto Collauto, Peter‐Leon Hagedoorn, Madalina Alexandru, Maike Henschel, Shahram Kordasti, Maria Andrea Mroginski, Maxie M. Roessler, Kourosh H. Ebrahimi   +9 more
wiley   +1 more source

On the chemistry of 1-pyrroline in solution and in the gas phase

Scientific Reports, 2017
1-Pyrroline has a highly characteristic odor, which is employed by living organisms for chemical signaling and other purposes, but the mechanism whereby this odor is formed remains poorly understood.
Xiaoping Zhang, Konstantin Chingin, Dacai Zhong, Juchao Liang, Yongzhong Ouyang, Huanwen Chen   +5 more
doaj   +1 more source