Results 61 to 70 of about 1,123,387 (315)

Mass spectrometry of alkylbenzenes and related compounds. Part I. Gas-phase ion chemistry of alkylbenzene radical cations

open access: yes, 1990
Kuck D. Mass spectrometry of alkylbenzenes and related compounds. Part I. Gas-phase ion chemistry of alkylbenzene radical cations. Mass Spectrometry Reviews.
Dietmar Kuck, Kuck, Dietmar
core   +1 more source

Mass Spectrometry Imaging of Microbes

open access: yes, 2020
Microbes influence many aspects of human life from the environment to health, yet evaluating their biological processes at the chemical level can be problematic. Mass spectrometry imaging (MSI) enables direct evaluation of microbial chemical processes at
Yang, Hyojik   +3 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A cosmogenic 10Be anomaly during the late Miocene as independent time marker for marine archives

open access: yesNature Communications
Cosmogenic nuclide dating relies on the constancy of production and incorporation of radionuclides in geological archives. Anomalous deviations from constancy during the Holocene or Pleistocene are frequently used as global benchmarks to harmonize ...
Dominik Koll   +9 more
doaj   +1 more source

Plasma lipidomic analysis reveals strong similarities between lipid fingerprints in human, hamster and mouse compared to other animal species

open access: yesScientific Reports, 2018
Cardiovascular diseases are often associated with impaired lipid metabolism. Animal models are useful for deciphering the physiological mechanisms underlying these pathologies.
Zied Kaabia   +9 more
doaj   +1 more source

Spatial lipidomics reveals brain region-specific changes of sulfatides in an experimental MPTP Parkinson’s disease primate model

open access: yesnpj Parkinson's Disease, 2023
Metabolism of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) to the neurotoxin MPP+ in the brain causes permanent Parkinson’s disease-like symptoms by destroying dopaminergic neurons in the pars compacta of the substantia nigra in humans and non ...
Ibrahim Kaya   +8 more
doaj   +1 more source

Liquid chromatography-tandem mass spectrometry - Application in the clinical laboratory [PDF]

open access: yes, 2003
This review provides a concise survey of liquid chromatography tandem mass spectrometry (LCTMS) as an emerging technology in clinical chemistry. The combination of two mass spectrometers with an interposed collision cell characterizes LCTMS as an ...
Michael Vogeser, Vogeser, Michael
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Correction: Wu et al. A Novel Truncated DNAzyme Modified Paper Analytical Device for Point-of-Care Test of Copper Ions in Natural Waters. Chemosensors 2022, 10, 72

open access: yesChemosensors
The authors make the following corrections to the published paper [...]
Jiayi Wu   +5 more
doaj   +1 more source

Identification of Aflatoxins by Quadrupole Mass Spectrometry/Mass Spectrometry

open access: yesJournal of AOAC INTERNATIONAL, 1984
Abstract MS/MS daughter experiments were recorded for aflatoxins B1, B2, G1, G2, M1, M2, and aflatoxicol, using 3 ionization modes. Daughters were recorded from the molecular ion (M+) using electron impact ionization (EI). Daughters from the protonated molecules (MH+) were recorded in the positive ion mode and the daughters from the ...
R D, Plattner   +2 more
openaire   +2 more sources

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