Results 61 to 70 of about 5,492,223 (387)
Workflow automation in liquid chromatography mass spectrometry [PDF]
, 2019 We describe the fully automated workflow path developed for the ingest and analysis of liquid chromatography mass spectrometry (LCMS) data. With the help of this computational workflow, we were able to replace two human work days to analyze data with two
Baidoo, E +3 more
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Nature Methods, 2019 Hydrogen deuterium exchange mass spectrometry (HDX-MS) is a powerful biophysical technique being increasingly applied to a wide variety of problems.
G. Masson +41 more
semanticscholar +1 more source
Native mass spectrometry-A valuable tool in structural biology.
Journal of Mass Spectrometry, 2020 Proteins and the complexes they form with their ligands are the players of cellular action. Their function is directly linked with their structure making the structural analysis of protein-ligand complexes essential.
Marie Barth, Carla Schmidt
semanticscholar +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Molecular Systems Biology, 2023 The lifespans of proteins range from minutes to years within mammalian tissues. Protein lifespan is relevant to organismal aging, as long‐lived proteins accrue damage over time.
John Hasper +4 more
doaj +1 more source
Coulomb crystal mass spectrometry in a digital ion trap [PDF]
, 2015 We present a mass spectrometric technique for identifying the masses and relative abundances of Coulomb-crystallized ions held in a linear Paul trap.
Deb, Nabanita +6 more
core +2 more sources
Reproducible molecular networking of untargeted mass spectrometry data using GNPS
Nature Protocols, 2019 Global Natural Product Social Molecular Networking (GNPS) is an interactive online small molecule–focused tandem mass spectrometry (MS2) data curation and analysis infrastructure.
Allegra T. Aron +41 more
semanticscholar +1 more source
FEBS Letters, EarlyView.This work presents the characterization of MvoDUF2193, a Methanococcus voltae (Mvo) protein from the domain of unknown function (DUF) 2193 family. We demonstrate that MvoDUF2193 binds a single [4Fe–4S] cluster per subunit and that cluster occupancy regulates the transition from an apo tetramer to a [4Fe–4S] monomeric form. This structural transition is
Emily M. Dieter +8 more
wiley +1 more source
Innovative Imaging Techniques: A Conceptual Exploration of Multi-Modal Raman Light Sheet Microscopy
Micromachines, 2023 Advances in imaging of microscopic structures are supported and complemented by adaptive visualization tools. These tools enable researchers to precisely capture and analyze complex three-dimensional structures of different kinds such as crystals ...
Steffen Manser +5 more
doaj +1 more source
Identification of a Widespread Palmitoylethanolamide Contamination in Standard Laboratory Glassware. [PDF]
, 2017 Introduction: Fatty acid ethanolamides (FAEs) are a family of lipid mediators that participate in a host of biological functions. Procedures for the quantitative analysis of FAEs include organic solvent extraction from biological matrices (e.g., blood ...
Angelini, Roberto +3 more
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