Results 111 to 120 of about 175,673 (317)

Fibroblast Transcriptomics in Molecular Diagnostics of a Comprehensive Dystonia Cohort

Annals of Neurology, EarlyView.
Objective Genomic sequencing leaves >50% of dystonia‐affected individuals without a diagnosis. Where DNA‐oriented approaches remain insufficient, integrating multiomics is essential to advance genome interpretation. Herein, we incorporated RNA sequencing (RNA‐seq) data from 167 patients with dystonia across a range of ages and presentations. Methods We
Alice Saparov, Ivana Dzinovic, Theresa Brunet, Vicente A. Yépez, Florian Hölzlwimmer, Elisabetta Indelicato, Birgit Assmann, Susann Badmann, Diana Ballhausen, Steffen Berweck, Felix Brechtmann, Melanie Brugger, Kevork Derderian, Felix Distelmaier, Philip Harrer, Denisa Harvanova, Petra Havrankova, Ann‐Kathrin Jaroszynski, Miriam Kolnikova, Robert Kopajtich, Anne Koy, Magdalena Krygier, Lukas Kunc, Katarina Kusikova, Oliver Maier, Maria Mazurkiewicz‐Bełdzińska, Christian Mertes, Ava Oberlack, Timo Roser, Alexandra Sitzberger, Ugo Sorrentino, Antonia M. Stehr, Katharina Vill, Matias Wagner, Holger Prokisch, Sylvia Boesch, Jan Necpal, Robert Jech, Juliane Winkelmann, Elisabeth Graf, Julien Gagneur, Matej Skorvanek, Michael Zech   +42 more
wiley   +1 more source

Development of both human connective tissue-type and mucosal-type mast cells in mice from hematopoietic stem cells with identical distribution pattern to human body [PDF]

, 2003
Naotomo Kambe, Hidefumi Hiramatsu, Mika Shimonaka, Hisanori Fujino, Ryuta Nishikomori, Toshio Heike, Mamoru Ito, Kimio Kobayashi, Yoshito Ueyama, Norihisa Matsuyoshi, Yoshiki Miyachi, Tatsutoshi Nakahata   +11 more
openalex   +1 more source

Nanoparticle‐Based Tolerogenic Vaccines: Next‐Generation Strategies for Autoimmune and Allergic Disease Therapies

Angewandte Chemie, EarlyView.
Nanoparticle‐based tolerogenic vaccines harness controlled antigen delivery and immunomodulation to establish tolerance in autoimmunity and allergy. This review outlines how nanoparticle design (size, shape, composition, administration route) influences biodistribution and immune‐cell targeting.
Benjamin E. Nachod, Ajay S. Thatte, Rohan Palanki, Michael J. Mitchell   +3 more
wiley   +1 more source

Mast cell histamine promotes the immunoregulatory activity of myeloid-derived suppressor cells

, 2014
Rebecca Martin, Sheinei Saleem, Lauren Folgosa, Hannah B. Zellner, Sheela Damle, Giang-Kim T Nguyen, John J. Ryan, Harry D. Bear, Anne‐Marie Irani, Daniel H. Conrad   +9 more
openalex   +1 more source

MrgX2 is a promiscuous receptor for basic peptides causing mast cell pseudo‐allergic and anaphylactoid reactions [PDF]

, 2019
Jak Grimes, Sapna Desai, Neil W. Charter, James Lodge, Rita Moita Santos, Albert Isidro‐Llobet, Andrew M. Mason, Zining Wu, Lawrence A. Wolfe, Lakshmi Anantharaman, Andrew R. Green, Angela Bridges, Deidre A. Dalmas Wilk, Andrew J. Brown   +13 more
openalex   +1 more source

The Mechanical Behavior of Dual TPU/Nylon 3D Printed Parts

Journal of Applied Polymer Science, EarlyView.
Graphical abstract illustrating dual‐material fused filament fabrication (FFF) of TPU and nylon, highlighting different material configurations (nylon outer/TPU core, TPU outer/nylon core, and alternating layers), the role of infill geometry in load transfer and ductility, and the resulting tensile and flexural performance trade‐offs between strength ...
Liam O'Connor
wiley   +1 more source

Perifollicular and Perivascular Mouse Skin Mast Cells Express Corticotropin-Releasing Hormone Receptor [PDF]

, 2006
Jill Donelan, James E. Marchand, Duraisamy Kempuraj, Nikoletta Papadopoulou, Dean Papaliodis, Theoharis C. Theoharides   +5 more
openalex   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

Mast Cell Frequency in Oral Squamous Cell Carcinoma [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Oral squamous cell carcinoma is the most common malignancy of the oral cavity. In solid tumors, cancer cells and stromal cells (fibroblasts, inflammatory cells, endothelial cells) play a role in tumor progression, angiogenesis ...
Najmeh Jafari, Seyed Mostafa Mahmoudi, Fatemeh Taherneghad   +2 more
doaj  

On the Role of Mast Cells and Their Proteases in the Severe COVID-19

Архивъ внутренней медицины
During the pandemic of the new coronavirus infection COVID-19 the question about the importance of mast cells and their proteases arose.   The aim of this study is to determine the role of mast cells and their proteases chymase and tryptase in the ...
A. V. Budnevsky, S. N. Avdeev, E. S. Ovsyannikov, I. A. Savushkina, O. N. Choporov, V. V. Shishkina, A. V. Pertsev, I. M. Perveeva, N. G. Alekseeva   +8 more
doaj   +1 more source