Results 211 to 220 of about 175,673 (317)

Mast Cells and Interstitial Cystitis/Bladder Pain Syndrome Revisited. [PDF]

Int Urogynecol J
Ruetten H, Ritts R, Namugosa M, Li W, Evans R, Badlani G, Walker SJ.   +6 more
europepmc   +1 more source

Association of autoimmune diseases with biologic agents targeting type 2 immunity: An observational study using a claims database

Rheumatology &Autoimmunity, EarlyView.
This observational study assessed the association between anti‐type 2 biologic agents and the occurrence of autoimmune diseases using a large real‐world claims database. Anti‐IL‐5 and anti‐IgE therapies were associated with an increased occurrence of autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE ...
Shoichiro Inokuchi
wiley   +1 more source

IgG:FcγRIIb Signaling on Mast Cells Blocks Allergic Airway Inflammation. [PDF]

Int J Mol Sci
Kanagaratham C, El Ansari YS, Furiness KN, Oettgen HC.   +3 more
europepmc   +1 more source

Associations between early life exposure to parvovirus and antibiotic treatment and the occurrence and severity of later chronic enteropathy in dogs

Veterinary Record, EarlyView.
Abstract Background Canine parvovirus (CPV) infection is reportedly associated with chronic enteropathy (CE), but infected puppies are often treated with antibiotics, which may also promote CE. This study aims to compare the presence and severity of CE among dogs that were CPV‐infected, treated with antibiotics or healthy during puppyhood.
Sharon Kuzi, Neta Goldstein, Gila Sutton, Gilad Segev   +3 more
wiley   +1 more source

Heterogeneity of active mast cells, endothelial cells, and fibroblasts in hemophilic arthritis defined by synovial single-cell sequencing. [PDF]

Sci Rep
Lin K, Fan S, Yang X, Hou W, Zhang J, Liao J, Han L, Peng P, Xiao F, Fang W, He X, Tian J, Lu S, Yang F, Wei Q, He M.   +15 more
europepmc   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

Tissue Distribution and Phenotype of Human Mast Cells in BRGSF and NSG-SGM3-IL15 Humanized Mice. [PDF]

Allergy
Worrall WPM, Serhan N, Karrich JJ, El Samrout C, Ekren R, Kamphuis JBJ, Hateb C, Leveque E, Loste A, Apoil PA, Gaudenzio N, Reber LL.   +11 more
europepmc   +1 more source

Single‐cell RNA sequencing revealed the T‐cell heterogeneity and exhaustion subsets of Helicobacter pylori‐induced gastritis‐to‐cancer transformation

VIEW, EarlyView.
H. pylori infection is a major cause of stomach cancer, but its effect on immune cells in tumors is unclear. Using single‐cell sequencing, we mapped the stomach tumor environment and discovered a specific exhausted T‐cell subtype, marked by the FYB1 gene, that is abundant in H. pylori‐positive tumors and linked to patient prognosis. Our findings reveal
Yanhui Yang, Yanxia Liu, Xiaole Guo, Zhaorun Li, Ziyu Liu, Shuming Zhang, Yuma Yang, Jun Liu, Shoucheng Ma, Linke Ma, Xianmei Chen, Xue Li, Yuanyuan Tang, Xiaoling Ding, Xiaofei Li, Qian Hao, Yanjie You, Tingting Yang, Qingrui Li, Xue Zhang, Sihan Zhang, Hengjun Gao, Shengjuan Hu   +22 more
wiley   +1 more source

New insight into role of mast cells in erythrocyte homeostasis and clearance under oxidative stress conditions <i>in vivo</i>. [PDF]

Biochem Biophys Rep
Sharma P, Suleman M, Puri N.
europepmc   +1 more source

Chinese Guidelines for Diagnosis and Treatment of Chronic Rhinosinusitis (2024)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Chronic rhinosinusitis (CRS), a complex inflammatory disease with heterogeneous pathogenesis, demands evolving evidence‐based strategies. Since the 2018 Chinese guidelines and EPOS2020, international advances in CRS immunopathology and biologics have revolutionized therapeutic approaches, particularly through phenotype–endotype classification ...
Subspecialty Group of Rhinology, Editorial Board of Chinese Journal of Otorhinolaryngology Head and Neck Surgery, Subspecialty Group of Rhinology, Society of Otorhinolaryngology Head and Neck Surgery, Chinese Medical Association   +4 more
wiley   +1 more source