Results 51 to 60 of about 316,824 (311)

Steering Mast Cells or Their Mediators as a Prospective Novel Therapeutic Approach for the Treatment of Hematological Malignancies

open access: yesFrontiers in Oncology, 2021
Tumor cells require signaling and close interaction with their microenvironment for their survival and proliferation. In the recent years, Mast cells have earned a greater importance for their presence and role in cancers. It is known that mast cells are
Deeksha Mehtani, Niti Puri
doaj   +1 more source

Comparative analysis of mast cell count in normal oral mucosa and oral pyogenic granuloma [PDF]

open access: yes, 2011
Introduction: Mast cells are large granular cells that arise from a multipotent CD 34+ precursor in the bone marrow normally distributed throughout connective tissues.
Dahiya, Parveen   +3 more
core   +1 more source

Differential Diagnoses of Systemic Mastocytosis in Routinely Processed Bone Marrow Biopsy Specimens: A Review [PDF]

open access: yes, 2010
Diagnosis of systemic mastocytosis (SM) is mainly based on the morphological demonstration of compact mast cell infiltrates in various tissue sites. In almost all patients such infiltrates are detected in the bone marrow.
Horny, H. -P., Sotlar, K., Valent, P.
core   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

open access: yesFEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang   +9 more
wiley   +1 more source

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

open access: yesCancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada   +16 more
wiley   +1 more source

The MAterials Simulation Toolkit (MAST) for atomistic modeling of defects and diffusion [PDF]

open access: yesComputational Materials Science 126 (2017) 90-102, 2016
The MAterials Simulation Toolkit (MAST) is a workflow manager and post-processing tool for ab initio defect and diffusion workflows. MAST codifies research knowledge and best practices for such workflows, and allows for the generation and management of easily modified and reproducible workflows, where data is stored along with workflow information for ...
arxiv   +1 more source

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

Histamine and TNF-α release by rat peritoneal mast cells stimulated with Trichomonas vaginalis

open access: yesParasite, 2011
Mast cells have been reported to be predominant in the vaginal smears of patients infected with T. vaginalis. In this study, we investigated whether T. vaginalis could induce mast cells to migrate and to produce TNF-α and histamine.
Im S.J.   +6 more
doaj   +1 more source

Evaluating Trustworthiness of AI-Enabled Decision Support Systems: Validation of the Multisource AI Scorecard Table (MAST) [PDF]

open access: yesarXiv, 2023
The Multisource AI Scorecard Table (MAST) is a checklist tool based on analytic tradecraft standards to inform the design and evaluation of trustworthy AI systems. In this study, we evaluate whether MAST is associated with people's trust perceptions in AI-enabled decision support systems (AI-DSSs).
arxiv  

Mast cells and metabolic syndrome [PDF]

open access: yes, 2012
Mast cells are critical effectors in the development of allergic diseases and in many immunoglobulin E-mediated immune responses. These cells exert their physiological and pathological activities by releasing granules containing histamine, cytokines ...
Shi, Guo-Ping, Zhang, Jie
core   +1 more source

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