Results 51 to 60 of about 143,658 (169)

T Cell-Mediated Modulation of Mast Cell Function: Heterotypic Adhesion-Induced Stimulatory or Inhibitory Effects

open access: yesFrontiers in Immunology, 2012
Close physical proximity between mast cells and T cells has been demonstrated in several T cell mediated inflammatory processes such as rheumatoid arthritis and sarcoidosis.
Yoseph A. Mekori, Alon Y Hershko
doaj   +1 more source

Polo-like kinase-1 as a novel target in neoplastic mast cells: demonstration of growth-inhibitory effects of small interfering RNA and the Polo-like kinase-1 targeting drug BI 2536

open access: yesHaematologica, 2011
Background In advanced systemic mastocytosis the response of neoplastic mast cells to conventional drugs is poor and the prognosis is bad. Current research is, therefore, attempting to identify novel drug targets in neoplastic mast cells.
Barbara Peter   +13 more
doaj   +1 more source

Mast cells and canine mast cell tumours. A review [PDF]

open access: yesVeterinary Quarterly, 2004
This article reviews the literature on mast cells and tumours derived from mast cells in the dog. Mast cells play a central role in inflammatory and immune reactions. Mast cells, normal and neoplastic, contain and release important biologically active substances: heparin, histamine, eosinophilic chemotactic factor and proteolytic enzymes.
openaire   +2 more sources

Immunological and regenerative aspects of hepatic mast cells in liver allograft rejection and tolerance.

open access: yesPLoS ONE, 2012
The precise roles of mast cells in liver allograft rejection and tolerance are still unknown. This study aimed to explore the roles of mast cells in immune regulation and liver regeneration for tolerance induction by using rat models of orthotopic liver ...
Toshiaki Nakano   +11 more
doaj   +1 more source

Glucagon and insulin immunopositivity of mast cells in porcine gallbladder

open access: yesBulgarian Journal of Veterinary Medicine
It is well known that mast cells produce and release biologically active substances such as histamine, heparin, proteases, leukotrienes, cytokines, chemokines and growth factors. According to the avail-able scientific literature on that topic this is the
I. Stefanov, S. Stefanov, M. Gulubova
doaj   +1 more source

Mast cell disease [PDF]

open access: yesPostgraduate Medical Journal, 1967
T I, McBride, G A, McDonald, W P, Duguid
openaire   +2 more sources

Neoadjuvant chemotherapy induces phenotypic mast cell changes in high grade serous ovarian cancer

open access: yesJournal of Ovarian Research
Background High grade serous ovarian cancer (HGSOC) is the most lethal gynecologic malignancy in which patients have still yet to respond meaningfully to clinically available immunotherapies. Hence, novel immune targets are urgently needed. Our past work
Julia McAdams   +8 more
doaj   +1 more source

Mast Cell Frequency in Oral Squamous Cell Carcinoma [PDF]

open access: yesJournal of Mazandaran University of Medical Sciences
Background and purpose: Oral squamous cell carcinoma is the most common malignancy of the oral cavity. In solid tumors, cancer cells and stromal cells (fibroblasts, inflammatory cells, endothelial cells) play a role in tumor progression, angiogenesis ...
Najmeh Jafari   +2 more
doaj  

Correlation of intratumoral mast cell quantity with psychosocial distress in patients with pancreatic cancer: the PancStress study

open access: yesScientific Reports
Mast cells are commonly found in pancreatic ductal adenocarcinoma (PDAC), yet their role in the disease remains uncertain. Although mast cells have been associated with depression in several diseases, their connection to PDAC in this context remains ...
Alicia Sitte   +20 more
doaj   +1 more source

Mast cell sarcoma with concurrent mast cell leukaemia [PDF]

open access: yesBritish Journal of Haematology, 2020
Lauren M. Raymond   +7 more
openaire   +2 more sources

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