Results 21 to 30 of about 177,875 (202)

Successful treatment of provisional cutaneous mastocytosis with interferon alpha

Indian Journal of Dermatology, 2016
Mastocytosis is a disorder characterized by the clonal proliferation of mast cells and their accumulation in skin, bone marrow, liver, and spleen. Cutaneous mastocytosis presents in children in over 90% of the cases and any cutaneous manifestation in an ...
Andrea Rosario, Ramesh M Bhat
doaj   +2 more sources

Bullous mastocytosis

Indian Journal of Dermatology, 2007
Mastocytosis is a condition characterized by the disorderly infiltration of mast cells in several tissues and comprises many different clinical situations varying from indolent cutaneous forms to malignant and systemic conditions. Bullous mastocytosis is
Nayak Surajit, Acharjya Basanti, Devi Basanti, Behera Samira   +3 more
doaj   +1 more source

Rare Clinical Image of Cutaneous Mastocytosis

Journal of Clinical and Diagnostic Research
Mastocytosis, a rare condition also referred to as a clonal bone marrow disorder, is characterised by an excessive presence of CD34+ mast cell progenitors and functionally impaired mast cells. This disorder can affect both adults and children, leading to
Shubham Khanke, Mujahid Khan, Keyur Dudhat, Pratiksha Mahure   +3 more
doaj   +2 more sources

Cutaneous mastocytosis - clinical heterogeneity

International Archives of Allergy and Immunology, 2002
Cutaneous mastocytosis (CM) encompasses several distinct patterns of disease which can be distinguished by the type of skin lesions, age of onset, familial occurrence, noncutaneous involvement, associated c-kit mutations, and prognosis.
Henz, Beate M., Hartmann, Karin
core   +4 more sources

Hidden in Plain Sight: Systemic Mastocytosis Manifesting as Isolated Hepatosplenomegaly in the Absence of Cutaneous and Classical Manifestations-A Case Report and Literature Review. [PDF]

Clin Case Rep
ABSTRACT Systemic mastocytosis (SM) is a rare clonal myeloproliferative neoplasm typically characterized by cutaneous lesions and mediator‐release symptoms. Presentations dominated by visceral organ involvement without skin findings are uncommon and pose a significant diagnostic challenge, often mimicking hematologic malignancies.
Sadam Zeb M, Mian UU, Khan K, Gulalay A, Hameed A, Malook A, Saeed E, Khan S, Mujtaba M, Kamil KA.   +9 more
europepmc   +2 more sources

Cutaneous mastocytosis in childhood

Allergologie select, 2022
Mastocytoses are characterized by clonal proliferation of mast cells in various tissues. In childhood, cutaneous mastocytosis (CM) occurs almost exclusively. It is confined to the skin, and has a good prognosis. The most common form is the maculopapular cutaneous mastocytosis (MPCM), formerly called urticaria pigmentosa. A distinction is made between a
Nemat, Katja, Abraham, Susanne
openaire   +3 more sources

Chronic Spontaneous Urticaria and Psychiatric Symptoms: The Blood-Brain Barrier Hypothesis. [PDF]

Exp Dermatol
ABSTRACT Chronic spontaneous urticaria (CSU) is a mast cell‐driven inflammatory disease frequently accompanied by anxiety, depression, sleep disturbance, fatigue, and impaired quality of life. Pruritus, disturbed sleep, psychosocial burden, and treatment‐related effects are established contributors to this neuropsychiatric and functional burden ...
Konstantinou GN, Warsh JJ, Blumberger DM, Kloiber S, Konstantinou GN.   +4 more
europepmc   +2 more sources

KIT mutation analysis in mast cell neoplasms: recommendations of the European competence network on mastocytosis [PDF]

, 2015
Although acquired mutations in KIT are commonly detected in various categories of mastocytosis, the methodologies applied to detect and quantify the mutant type and allele burden in cells and various tissues are poorly defined.
T. Haferlach, Reiter, A., Sperr, W. R., Akin, C, Valent, P., C. Akin, Garcia-Montero, A., G. Hoermann, Broesby-Olsen, S, Triggiani, M, Escribano, L, Hartmann, K.., Kluin-Nelemans, H. C., Cross, N.C.P., J. Gotlib, A. Reiter, Hermine, O., Akin, C., K. Sotlar, Haferlach, T, S. Broesby Olsen, Hoermann, G., TRIGGIANI, MASSIMO, P. Valent, A. Garcia Montero, Metcalfe, D. D., Sperr, W R, Broesby-Olsen, S., Gotlib, J, Kristensen, T. K., Arock, M, N. C. P. Cross, Schwaab, J., M. Arock, K. Hartmann, Schwaab, J, Metcalfe, D D, Escribano, L., O. Hermine, Kluin-Nelemans, H.C., Hermine, O, W. R. Sperr, J. Schwaab, Hoermann, G, Triggiani, M., Metcalfe, D.D., Cross, N C P, Horny, H.-P., Kluin-Nelemans, H C, Sotlar, K., D. D. Metcalfe, Sperr, W.R., Horny, H-P, Valent, P, Orfao, A., P. Dubreuil, Reiter, A, T. K. Kristensen, Orfao, A, Dubreuil, P., A. Orfao, Gotlib, J., L. Escribano, Sotlar, K, Kristensen, T.K., Hartmann, K., Cross, N. C. P., Haferlach, T., Dubreuil, P, Kielsgaard Kristensen, Thomas, Arock, M., Garcia-Montero, A, H. C. Kluin Nelemans, H. P. Horny, Hartmann, K, Valent, Peter, Orfao, Alberto, García-Montero, Andrés, Arock, Michel, Escribano, Luis   +79 more
core   +1 more source

Bullous disease in infant: think of cutaneous mastocytosis

PAMJ Clinical Medicine, 2020
Mastocytosis is a rare disease. The cutaneous form is the most frequent. There are several clinical forms of cutaneous mastocytosis including the bullous form which is rare.
Kaoutar Achehboune, Khadija Elboukhari, Hanane Baybay, Sara Elloudi, Fatima Zahra Mernissi   +4 more
doaj   +1 more source

Urticaria pigmentosa and systemic mastocytosis

Clinical Case Reports, 2023
Key Clinical Message Additional investigations for systemic involvement should be initiated once the diagnosis of cutaneous mastocytosis has been established in an adult patient.
Jonathan Keow, Benjamin Chin‐Yee, Cyrus C. Hsia, Kara Robertson   +3 more
doaj   +1 more source