Results 41 to 50 of about 177,875 (202)

Localized Pseudoxanthomatous Mastocytosis of Vulva

Indian Journal of Paediatric Dermatology, 2021
Cutaneous mastocytosis (CM) is a mast cell proliferative disorder that is common in the pediatric age group. Common entities are urticaria pigmentosa, solitary mastocytoma, telangiectasia macularis eruptive perstans. and diffuse CM.
Shivi Nijhawan, Manisha Nijhawan, Savita Agarwal   +2 more
doaj   +1 more source

Mastocytosis in children:A protocol for management

, 2008
Mastocytosis is characterized by an increased number of mast cells with an abnormal growth and accumulation in one or more organs. In most children mastocytosis is limited to the skin (cutaneous mastocytosis) and often transient as compared with that in ...
Pasmans, SGMA, Pasmans, Suzanne G. M. A., Hollander, Jan, Oranje, Arnold, Heide, Rogier, Van Gysel, Dirk, van Gysel, D, De Groot, Hans, Den Hollander, Jan C., Oranje, Arnold P., De Monchy, Jan G. R., Heide, R, de Groot, H, Beishuizen, Auke, Van Doormaal, Jasper J., van Doormaal, JJ, de Monchy, JGR, Dutch National Mastocytosis Work Group   +17 more
core   +2 more sources

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source

Cutaneous Manifestations in Mastocytosis: Update [PDF]

, 2020
Introdução: As mastocitoses caraterizam-se pela expansão clonal de mastócitos, com acumulação de mastócitos morfológica e imunofenotipicamente anormais em diferentes órgãos. A pele é o órgão mais frequentemente envolvido.
Fernandes, Iolanda, Selores, Manuela, Ferreira, Sandra, Cabral, Renata, Lima, Margarida, Machado, Susana   +5 more
core   +1 more source

Case Report - Cutaneous mastocytosis: Report of six cases [PDF]

, 2006
Cutaneous mastocytosis is a rare infiltrative disorder of the skin. Though often asymptomatic, systemic features may be associated with any clinical pattern of the disorder at any age group.
Arun C. Inamadar, Aparna Palit
core   +1 more source

Differential Roles for IL‐4Rα and IL‐13Rα1 in Immune Cell Infiltration and Epithelial Remodeling in Experimental Eosinophilic Gastritis

Allergy, EarlyView.
This study described the development of an experimental model for eosinophilic gastritis (EoG). Experimental EoG recapitulates histopathological features of human disease. including foveolar elongation, fibrosis, eosinophilia, mastocytosis and shared transcriptional programs.
Anish Dsilva, Shraddha Sharma, Shireen Barakey, Ariel Wagner, Alice Keisar, Tali Bar‐on, Michal Itan, Ariel Munitz   +7 more
wiley   +1 more source

Updated EAACI Statement on Drug Hypersensitivity Skin Testing: Methodology and Non‐Irritative Concentrations

Allergy, EarlyView.
ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud, Lene Heise Garvey, Elizabeth Phillips, Michael Ardern‐Jones, Sevim Bavbek, Patrizia Bonadonna, Jean‐Christoph Caubet, Ana‐Maria Copaescu, Valentina Gueli, Jose Julio Laguna, Ricardo Madrigal‐Burgaleta, Francesca Mori, Vito Sabato, Maria J Torres, Knut Brockow   +14 more
wiley   +1 more source

An Extended Transcriptomic Landscape of Human Skin Mast Cells: Unveiling Lineage‐Specific Noncoding RNA Dynamics in FcεRI Activation

Allergy, EarlyView.
FcεRI cross‐linking triggers widespread transcriptional reprogramming in human skin mast cells (> 5000 genes, > 6400 promoters, and 48 novel mast cell‐enriched lncRNAs). Breast skin and foreskin mast cells share core transcriptional programs but differ selectively in tryptase isoenzymes and IL‐8/IL‐1RA release.
Gürkan Bal, Kristin Franke, Stefan Frischbutter, Shiva Raj Tripathi, Kayoko Yasuzawa, Jordan A. Ramilowski, Michihira Tagami, Takeya Kasukawa, Michiel de Hoon, Jay W. Shin, Piero Carninci, Torsten Zuberbier, Magda Babina   +12 more
wiley   +1 more source

Clinical observations in cutan mastocytosis [PDF]

Orvosi Hetilap, 2013
Introduction: Mastocytosis is a clonal mast cell proliferative disease, devided into cutaneous and systemic forms. The characteristic symptoms are caused by neoplastic mast cell infiltrations in different organs and/or the release of mediators. Aim: The aim of the authors was to summarize their clinical observations in patients with mastocytosis ...
Noémi, Mihalik, Bernadett, Hidvégi, Judit, Hársing, Judit, Várkonyi, Judit, Csomor, Ilona, Kovalszky, Márta, Marschalkó, Sarolta, Kárpáti   +7 more
openaire   +2 more sources

Knockdown of mitotically associated long non‐coding RNA dysregulates endothelial functions, transcriptome and proteome

The Journal of Physiology, EarlyView.
Abstract figure legend Downregulation of mitotically associated long non‐coding RNA (MANCR) disturbs transcriptome and proteome in endothelial cells, possibly leading to endothelial and vascular dysfunction in preeclampsia. Abstract Preeclampsia (PE) is a hypertensive disorder during pregnancy, which is characterized by a wide spectrum of endothelial ...
Si‐Yan Zhang, Chi Zhou, Jing Zheng
wiley   +1 more source