Results 61 to 70 of about 10,225 (204)

Drug hypersensitivity reactions and allergy in patients with mastocytosis [PDF]

, 2017
Mastocytosis is a rare myeloproliferative disease caused by excessive proliferation and accumulation of mast cells in the skin and internal organs. The most common variant of mastocytosis in children is cutaneous mastocytosis.
Barbara Kwiecińska, Roman Nowicki, Hanna Ługowska-Umer, Justyna H. Czarny, Marek B. Niedoszytko, Monika Sikorska, Magdalena Lange, Aleksandra Górska   +7 more
core   +1 more source

Mastocitose bolhosa na criança: relato de caso Bullous mastocytosis in child: case report

Anais Brasileiros de Dermatologia, 2005
A mastocitose é doença rara, definida como a infiltração desordenada de mastócitos em vários tecidos. Compreende diferentes quadros clínicos, variando de formas cutâneas indolentes a condições sistêmicas e malignas. O termo mastocitose bolhosa descreve a
Ana Lúcia França da Costa, Teresinha Castelo Branco Carvalho, Ana Virginia Lopes de Sousa   +2 more
doaj   +1 more source

Enhanced PIEZO1 expression in mast cells of mastocytosis skin lesions: Relevance to Darier's sign

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Yoshiaki Kobayashi, Nobuhiro Nakano, Nguyen Quoc Vuong Tran, Yuki Nakamura, Lisa Minai, Takashi Okamoto, Daiki Nakagomi, Tatsuki R. Kataoka, Tatsuyoshi Kawamura, Atsuhito Nakao   +9 more
wiley   +1 more source

Dermatoscopy in diagnosing maculopapular cutaneous mastocytosis [PDF]

, 2016
The diagnosis of cutaneous mastocytosis is based on the clinical finding of the pigmented macules or papules, positive Darier's sign and a dermal infiltrate composed of mast cells that can be better visualized by the use of special stains (Giemsa or ...
Popadić Mirjana
core   +1 more source

Schwann Cell TRPA1, a Proalgesic Ion Channel, Mediates Neuroinflammation and Fibromyalgia‐Associated Behaviours in Mice

Journal of Neurochemistry, Volume 170, Issue 4, April 2026.
Cellular and molecular mechanisms contributing to TRPA1‐mediated mechanical and cold hypersensitivity and peripheral neuroinflammation in the reserpine‐induced experimental fibromyalgia model. (1) Macrophage‐originated reactive oxygen species (ROS; purple dots) target the transient receptor potential ankyrin 1 (TRPA1) channel localised in Schwann cells.
Evelyne Silva Brum, Maria Fernanda Pessano Fialho, Daniel Souza Monteiro de Araújo, Lorenzo Landini, Matilde Marini, Francesco De Logu, Romina Nassini, Sara Marchesan Oliveira   +7 more
wiley   +1 more source

A Link Between Allergy and Hematological Malignancies? Focus on Possible Mechanisms and the Potential Role of Biological Therapies

Clinical and Translational Allergy, Volume 16, Issue 3, March 2026.
ABSTRACT Immune dysregulation has been widely recognized in the international literature as an underlying condition for hematological malignancies and allergic disorders. This commonality has led researchers to study the potential association, positive or negative, between blood cancers and allergy, but the results remain unclear.
Stefania Isola, Luca Gammeri, Federica Nuccio, Alessandro Allegra, Giorgio Walter Canonica, Sebastiano Gangemi   +5 more
wiley   +1 more source

Diffuse Cutaneous Mastocytosis in a Child - a Case Report

, 2017
Mastocytosis refers to a group of diseases characterized by a clonal proliferation and accumulation of mast cells in one or more tissues/organs with different clinical presentations.
Mirjana Gajić-Veljić, Svetlana Popadić, Biljana Marenović, Miloš Nikolić   +3 more
core   +1 more source

Companion Diagnostics in Clinical Therapy: Current Applications and Future Directions

MedComm, Volume 7, Issue 3, March 2026.
Companion diagnostics use biomarker‐based assays to stratify patients for precision therapies, improving outcomes while reducing ineffective treatment and side effects. This review summarizes the evolution, regulatory landscape, clinical applications, and technological platforms of CDx, highlighting their role in biomarker‐driven precision therapy.
Yuesong Wu, Rou Xue, Xiangwen Luo, Jiangnan Liao, Zongbo Zhang, Jinhai Deng, Teng Liu, Xin Li, Zhe‐Sheng Chen, Mingzhu Yin   +9 more
wiley   +1 more source

Clinical features and course of cutaneous mastocytosis in 133 children

, 2016
The article reports on a clinical study on 133 children with cutaneous mastocytosis describing the clinical evolution over 10 years of follow up. The type of cutaneous mastocytosis, the clinical features, and the factors predicting long-term outcome are ...
SCHENA, DONATELLA, GIROLOMONI, Giampiero, TESSARI, Gianpaolo, GALVAN, Arturo   +3 more
core   +1 more source

Childhood Pseudoxanthomatousmastocytosis; Report of two cases

Indian Journal of Dermatopathology and Diagnostic Dermatology, 2018
Cutaneous mastocytosis (CM) is a mast cell proliferative disorder that commonly affects pediatric population. It has various clinical forms such as urticaria pigmentosa, solitary mastocytoma, telangiectasia macularis eruptiva perstans, diffuse CM, and ...
Bhabani S. T. P. Singh, Tapaswini Tripathy, Bikash Ranjan Kar, Surabhi Singh   +3 more
doaj   +1 more source