Results 71 to 80 of about 12,161 (224)

Loss of Function of TET2 Cooperates with Constitutively Active KIT in Murine and Human Models of Mastocytosis [PDF]

open access: yes, 2014
Systemic Mastocytosis (SM) is a clonal disease characterized by abnormal accumulation of mast cells in multiple organs. Clinical presentations of the disease vary widely from indolent to aggressive forms, and to the exceedingly rare mast cell leukemia ...
A Gerbaulet   +55 more
core   +3 more sources

Solitary mastocytoma presenting in an adult: report and literature review of adult-onset solitary cutaneous mastocytoma with recommendations for evaluation and treatment

open access: yesDermatology Practical & Conceptual, 2016
Background: Mastocytosis is either cutaneous (with skin-limited proliferation of mast cells) or systemic (with mast cells in extracutaneous sites). The onset of solitary mastocytoma in an adult is rare.
Philip R. Cohen
doaj   +1 more source

CD117 immunoexpression in canine mast cell tumours: correlations with pathological variables and proliferation markers [PDF]

open access: yes, 2007
Background Cutaneous mast cell tumours are one of the most common neoplasms in dogs and show a highly variable biologic behaviour. Several prognosis tools have been proposed for canine mast cell tumours, including histological grading and cell ...
Pires Maria A   +5 more
core   +2 more sources

CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas

open access: yesAmerican Journal of Hematology, Volume 101, Issue 1, Page 110-128, January 2026.
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley   +1 more source

Enhanced PIEZO1 expression in mast cells of mastocytosis skin lesions: Relevance to Darier's sign

open access: yes
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Yoshiaki Kobayashi   +9 more
wiley   +1 more source

Practical implications of the World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology: Categories and ancillary testing for subtyping of hematolymphoid tumors on FNA biopsy cytopathology using a pattern‐based approach

open access: yesCancer Cytopathology, Volume 134, Issue 1, January 2026.
Abstract The objective of the recently published World Health Organization Reporting System for Lymph Node, Spleen, and Thymus Cytopathology (WHO system) is to standardize the diagnostic approach to fine‐needle aspiration biopsies of hematolymphoid tissues.
Mats Ehinger   +4 more
wiley   +1 more source

Clinical Scoring of Cutaneous Mastocytosis

open access: yesActa Dermato-Venereologica, 2001
There are still many controversies in defining and evaluating mastocytosis. One of the aspects that is missing is a system for clinical evaluation of mastocytosis of the skin. A calculation based on a semi-quantitative analysis of three aspects of mastocytosis was designed. The method is called the scoring index of mastocytosis (SCORMA).
Heide, R.   +3 more
openaire   +3 more sources

Implementing PEN‐FAST for penicillin allergy delabeling in a high‐prevalence population

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 1, Page 57-63, January 2026.
Summary Background and objectives Self‐reported penicillin allergies lead to the use of broad‐spectrum antibiotics, increase drug resistance, and constitute an economic burden. The PEN‐FAST score aims to identify low‐risk patients for direct drug provocation tests (DPT) without prior skin testing with a reported negative predictive value (NPV) of over ...
Deniz Göcebe   +4 more
wiley   +1 more source

Expanding the Immunologic and Neuronal Landscape of IgE‐Mediated Anaphylaxis

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Anaphylaxis is a life‐threatening immunoglobulin E (IgE)‐mediated type I hypersensitivity reaction with rising prevalence and burden. It involves mast cell degranulation upon cross‐linking of antigen on mast cell‐bound IgE. Mechanisms of IgE‐mediated anaphylaxis remain incompletely understood, particularly the induction of systemic symptoms ...
Ruchi Biswas   +2 more
wiley   +1 more source

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