Results 11 to 20 of about 61,997 (154)

Urticaria pigmentosa and systemic mastocytosis

Clinical Case Reports, 2023
Key Clinical Message Additional investigations for systemic involvement should be initiated once the diagnosis of cutaneous mastocytosis has been established in an adult patient.
Jonathan Keow, Benjamin Chin‐Yee, Cyrus C. Hsia, Kara Robertson   +3 more
doaj   +1 more source

Cephalalgia against the background of systemic mastocytosis: a clinical case

Бюллетень сибирской медицины, 2021
The article presents a clinical case of comorbid pathology – development of migraine against the background of systemic mastocytosis. The classification and clinical manifestations of systemic mastocytosis, a rare blood disease, are given.This clinical ...
P. I. Kuznetsova, M. M. Tanashyan, A. L. Melikyan, I. N. Subortseva, A. A. Raskurazhev   +4 more
doaj   +1 more source

Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice

Haematologica, 2016
Systemic mastocytosis is a heterogeneous disease characterized by the accumulation of neoplastic mast cells in the bone marrow and other organ organs/tissues.
Celalettin Ustun, Michel Arock, Hanneke C. Kluin-Nelemans, Andreas Reiter, Wolfgang R. Sperr, Tracy George, Hans-Peter Horny, Karin Hartmann, Karl Sotlar, Gandhi Damaj, Olivier Hermine, Srdan Verstovsek, Dean D. Metcalfe, Jason Gotlib, Cem Akin, Peter Valent   +15 more
doaj   +1 more source

Biochemical markers predictive for bone marrow involvement in systemic mastocytosis

Haematologica, 2008
Systemic mastocytosis is characterized by bone marrow involvement, which requires a bone marrow biopsy for diagnostic work-up. We questioned whether bone marrow involvement could be predicted using biochemical markers.
Marjolein L. Donker, Jasper J. van Doormaal, Frederiek F. van Doormaal, Philip M. Kluin, Eveline van der Veer, Jan G.R. de Monchy, Ido P. Kema, Hanneke C. Kluin-Nelemans   +7 more
doaj   +1 more source

Adult mastocytosis: a review of the Santo António Hospital 's experience and an evaluation of World Health Organization criteria for the diagnosis of systemic disease [PDF]

Anais Brasileiros de Dermatologia, 2014
BACKGROUND: Mastocytosis is a clonal disorder characterized by the accumulation of abnormal mast cells in the skin and/or in extracutaneous organs. OBJECTIVES: To present all cases of mastocytosis seen in the Porto Hospital Center and evaluate the ...
Iolanda Conde Fernandes, Maria dos Anjos Teixeira, Ines Freitas, Manuela Selores, Rosario Alves, Margarida Lima   +5 more
doaj   +1 more source

Systemic Mastocytosis: Multidisciplinary Approach.

Mediterranean journal of hematology and infectious diseases, 2021
Systemic mastocytosis (SM) is a heterogeneous group of diseases that affect almost exclusively adults and are defined by the proliferation and accumulation of clonal mast cells (MC) in various tissues. Disease subtypes range from indolent to rare aggressive forms.
Roberta Zanotti, Massimiliano Bonifacio, Ilaria Tanasi, Donatella Schena, Giovanni Orsolini, Morena Tebaldi, Lara Crosera, Francesca Mastropaolo, Elisa Olivieri, Patrizia Bonadonna   +9 more
openaire   +3 more sources

Can Visual Hallucinations be Among the Neuropsychological Manifestations of Systemic Mastocytosis?: A Geriatric Case

Psychiatry and Clinical Psychopharmacology, 2021
Mast cells are considered sensors of environmental and emotional stress, exist in all body parts and are related to the pathway from stress to inflammation.
Ozge Kilic, Ugur Eser Yilmaz, Zeynep Komesli, A. Cenk Ercan, Mustafa Cetiner   +4 more
doaj   +1 more source

Review papers The role of KIT gene mutations in pathogenesis of pediatric mastocytosis

Przegląd Dermatologiczny, 2015
Mastocytosis is characterized by excessive proliferation and accumulation of mast cells in skin and/or other organs. Two forms of the disease, cutaneous and systemic mastocytosis, differ significantly in symptomatology and clinical course.
Joanna Dawicka, Magdalena Lange, Bartosz Wasąg, Bogusław Nedoszytko, Aleksandra Wilkowska, Roman Nowicki   +5 more
doaj   +1 more source

Development of symptom-focused outcome measures for advanced and indolent systemic mastocytosis: the AdvSM-SAF and ISM-SAF©

Orphanet Journal of Rare Diseases, 2021
Background Advanced systemic mastocytosis (AdvSM), indolent systemic mastocytosis (ISM), and smoldering systemic mastocytosis (SSM) are rare diseases characterized by neoplastic mast cell infiltration of more than one organ.
Fiona Taylor, Cem Akin, Roger E. Lamoureux, Brad Padilla, Tanya Green, Anthony L. Boral, Iyar Mazar, Brenton Mar, Alan L. Shields, Frank Siebenhaar   +9 more
doaj   +1 more source

The KIT and PDGFRA switch-control inhibitor DCC-2618 blocks growth and survival of multiple neoplastic cell types in advanced mastocytosis

Haematologica, 2018
Systemic mastocytosis is a complex disease defined by abnormal growth and accumulation of neoplastic mast cells in various organs. Most patients exhibit a D816V-mutated variant of KIT, which confers resistance against imatinib.
Mathias Schneeweiss, Barbara Peter, Siham Bibi, Gregor Eisenwort, Dubravka Smiljkovic, Katharina Blatt, Mohamad Jawhar, Daniela Berger, Gabriele Stefanzl, Susanne Herndlhofer, Georg Greiner, Gregor Hoermann, Emir Hadzijusufovic, Karoline V. Gleixner, Peter Bettelheim, Klaus Geissler, Wolfgang R. Sperr, Andreas Reiter, Michel Arock, Peter Valent   +19 more
doaj   +1 more source