Results 31 to 40 of about 65,460 (210)

Phenotypic and genotypic characteristics of mastocytosis according to the age of onset. [PDF]

PLoS ONE, 2008
Adult's mastocytosis is usually associated with persistent systemic involvement and c-kit 816 mutation, while pediatrics disease is mostly limited to the skin and often resolves spontaneously.
Fanny Lanternier, Annick Cohen-Akenine, Fabienne Palmerini, Frédéric Feger, Ying Yang, Yael Zermati, Stéphane Barète, Beatrix Sans, Cédric Baude, David Ghez, Felipe Suarez, Richard Delarue, Philippe Casassus, Christine Bodemer, Adeline Catteau, Frédérique Soppelsa, Katia Hanssens, Michel Arock, Hagay Sobol, Sylvie Fraitag, Danièle Canioni, Alain Moussy, Jean Marie Launay, Patrice Dubreuil, Olivier Hermine, Olivier Lortholary, AFIRMM network   +26 more
doaj   +1 more source

Delayed Diagnosis of Indolent Systemic Mastocytosis as the Cause of Unexplained Skin Rash: A Case Report

Case Reports in Oncology, 2023
Mastocytosis is a heterogeneous group of disorders in which mast cells exhibit clonal proliferation that infiltrates one or more organs. In cutaneous mastocytosis, the mast cells infiltrate the skin only, whereas systemic mastocytosis is diagnosed when ...
Awni Alshurafa, Mohammad Abu-Tineh, Feryal A. Ibrahim, Mahir Petkar, Mohamed A. Yassin   +4 more
doaj   +1 more source

How “benign” is cutaneous mastocytosis? A Danish registry-based matched cohort study

International Journal of Women's Dermatology, 2020
Background: There are limited estimates of the incidence rates (IRs) of mastocytosis, and only a few studies have addressed the long-term consequences of living with these diagnoses.
Line Kibsgaard, MD, PhD, Mette Deleuran, MD, Head of Department, Carsten Flohr, MD, Head of Department, Sinéad Langan, MD, Anne Braae Olesen, MD, PhD, Christian Vestergaard, MD, PhD   +5 more
doaj   +1 more source

Recalcitrant Cutaneous Mastocytosis Treated With Genetically Informed Targeted Therapy: A Case Report

International Journal of Dermatology and Venerology, 2023
Introduction:. Mastocytosis, a clonal proliferation of mast cells commonly involving the skin and bone marrow, has a varied clinical presentation ranging from cutaneous lesions to systemic disease.
Laura Gleason, Volkan Tekmen, Alexa Cohen, Safiyyah Bhatti, Burcu Beksac, Jisun Cha, Pierluigi Porcu, Neda Nikbakht   +7 more
doaj   +1 more source

Systemic mastocytosis in the elderly [PDF]

American Journal of Hematology, 2013
“Later onset” of systemic mastocytosis (SM) has been associated with a poorer prognosis. We examined clinical and laboratory findings, associated disorders, and survival in an older mastocytosis population. After receiving Mayo Clinic Institutional Review Board approval, we identified 42 patients aged 70 years and older at the time of diagnosis of SM ...
Joseph H, Butterfield, Catherine R, Weiler   +1 more
openaire   +2 more sources

Cephalalgia against the background of systemic mastocytosis: a clinical case

Бюллетень сибирской медицины, 2021
The article presents a clinical case of comorbid pathology – development of migraine against the background of systemic mastocytosis. The classification and clinical manifestations of systemic mastocytosis, a rare blood disease, are given.This clinical ...
P. I. Kuznetsova, M. M. Tanashyan, A. L. Melikyan, I. N. Subortseva, A. A. Raskurazhev   +4 more
doaj   +1 more source

KIT mutation analysis in mast cell neoplasms: recommendations of the European competence network on mastocytosis [PDF]

, 2015
Although acquired mutations in KIT are commonly detected in various categories of mastocytosis, the methodologies applied to detect and quantify the mutant type and allele burden in cells and various tissues are poorly defined.
T. Haferlach, Reiter, A., Sperr, W. R., Akin, C, Valent, P., C. Akin, Garcia-Montero, A., G. Hoermann, Broesby-Olsen, S, Triggiani, M, Escribano, L, Hartmann, K.., Kluin-Nelemans, H. C., Cross, N.C.P., J. Gotlib, A. Reiter, Hermine, O., Akin, C., K. Sotlar, Haferlach, T, S. Broesby Olsen, Hoermann, G., TRIGGIANI, MASSIMO, P. Valent, A. Garcia Montero, Metcalfe, D. D., Sperr, W R, Broesby-Olsen, S., Gotlib, J, Kristensen, T. K., Arock, M, N. C. P. Cross, Schwaab, J., M. Arock, K. Hartmann, Schwaab, J, Metcalfe, D D, Escribano, L., O. Hermine, Kluin-Nelemans, H.C., Hermine, O, W. R. Sperr, J. Schwaab, Hoermann, G, Triggiani, M., Metcalfe, D.D., Cross, N C P, Horny, H.-P., Kluin-Nelemans, H C, Sotlar, K., D. D. Metcalfe, Sperr, W.R., Horny, H-P, Valent, P, Orfao, A., P. Dubreuil, Reiter, A, T. K. Kristensen, Orfao, A, Dubreuil, P., A. Orfao, Gotlib, J., L. Escribano, Sotlar, K, Kristensen, T.K., Hartmann, K., Cross, N. C. P., Haferlach, T., Dubreuil, P, Kielsgaard Kristensen, Thomas, Arock, M., Garcia-Montero, A, H. C. Kluin Nelemans, H. P. Horny, Hartmann, K   +74 more
core   +1 more source

Fatal anaphylactic sting reaction in a patient with mastocytosis [PDF]

, 2008
We report on a 33-year-old female patient with indolent systemic mastocytosis and urticaria pigmentosa who died of an anaphylactic reaction after a yellow jacket sting.
Rueff, F., Wagner, N., Hagedorn, M., Przybilla, Bernhard, Fritze, D.   +4 more
core   +1 more source

Differential Diagnoses of Systemic Mastocytosis in Routinely Processed Bone Marrow Biopsy Specimens: A Review [PDF]

, 2010
Diagnosis of systemic mastocytosis (SM) is mainly based on the morphological demonstration of compact mast cell infiltrates in various tissue sites. In almost all patients such infiltrates are detected in the bone marrow.
Horny, H. -P., H.-P. Horny, Valent, P., P. Valent, Sotlar, K., K. Sotlar   +5 more
core   +1 more source

Definitions, Criteria and Global Classification of Mast Cell Disorders with Special Reference to Mast Cell Activation Syndromes: A Consensus Proposal [PDF]

, 2011
Activation of tissue mast cells (MCs) and their abnormal growth and accumulation in various organs are typically found in primary MC disorders also referred to as mastocytosis.
Triggiani, Massimo, Rudolf Valenta, Michel Arock, Arock, Michel, Philip Lieberman, Massimo Triggiani, Butterfield, Joseph H., Boguslaw Nedoszytko, Lawrence B. Schwartz, Dean D. Metcalfe, Alberto Orfao, Wolfgang R. Sperr, Valent, Peter, Brockow, Knut, Orfao, Alberto, Melody C. Carter, Karin Hartmann, Karl Sotlar, Schwartz, Lawrence B., Horny, Hans-Peter, Luis Escribano, Peter Valent, Cem Akin, Castells, Mariana, Escribano, Luis, Lieberman, Philip, Knut Brockow, Joseph H. Butterfield, Valenta, Rudolf, Hartmann, Karin, Metcalfe, Dean D., Hans-Peter Horny, Mariana Castells, Carter, Melody C., Sperr, Wolfgang R., Akin, Cem, Sotlar, Karl, Nedoszytko, Boguslaw   +37 more
core   +1 more source