Results 11 to 20 of about 917,566 (209)
Urticaria pigmentosa and systemic mastocytosis [PDF]
Clinical Case Reports, 2023 Key Clinical Message Additional investigations for systemic involvement should be initiated once the diagnosis of cutaneous mastocytosis has been established in an adult patient.
Jonathan Keow +3 more
doaj +5 more sources
CD30 in Systemic Mastocytosis [PDF]
Immunology and Allergy Clinics of North America, 2014 CD30 is a transmembrane receptor, normally not expressed by mast cells, which regulates proliferation/apoptosis and antibody responses. Aberrant expression of CD30 by mastocytosis mast cells and interaction with its ligand CD30L (CD153) appears to play an important role in the pathogenesis and clinical presentation of systemic mastocytosis.
van Anrooij, Bjorn +3 more
openaire +4 more sources
Biochemical markers predictive for bone marrow involvement in systemic mastocytosis [PDF]
Haematologica, 2008 Systemic mastocytosis is characterized by bone marrow involvement, which requires a bone marrow biopsy for diagnostic work-up. We questioned whether bone marrow involvement could be predicted using biochemical markers.
Marjolein L. Donker +7 more
doaj +3 more sources
Review papers The role of KIT gene mutations in pathogenesis of pediatric mastocytosis
Przegląd Dermatologiczny, 2015 Mastocytosis is characterized by excessive proliferation and accumulation of mast cells in skin and/or other organs. Two forms of the disease, cutaneous and systemic mastocytosis, differ significantly in symptomatology and clinical course.
Joanna Dawicka +5 more
doaj +2 more sources
Advanced systemic mastocytosis: from molecular and genetic progress to clinical practice [PDF]
Haematologica, 2016 Systemic mastocytosis is a heterogeneous disease characterized by the accumulation of neoplastic mast cells in the bone marrow and other organ organs/tissues.
Celalettin Ustun +15 more
doaj +3 more sources
Diffuse large B cell lymphoma coexistence with systemic mastocytosis [PDF]
Journal of Cancer Research and Practice, 2016 Systemic mastocytosis is a rare disease and characterized by excessive mast cell accumulation in one or multiple organs. One subtype of systemic mastocytosis is systemic mastocytosis-associated clonal hematological non-mast cell lineage disease (SM-AHMND)
Sheng-Hsuan Chien +8 more
doaj +2 more sources
Increased TIM-3 and GAL-9 serum levels in patients with advanced systemic mastocytosis. [PDF]
, 2023 BACKGROUND Systemic mastocytosis is characterized by expansion of clonal mast cells in various tissues. Several biomarkers with diagnostic and therapeutic potential have recently been characterized in mastocytosis, such as the serum marker tryptase ...
Peter Valent +19 more
core +3 more sources
Proposed global prognostic score for systemic mastocytosis: a retrospective prognostic modelling study [PDF]
, 2021 [Background]: Several risk stratification models have been proposed in recent years for systemic mastocytosis but have not been directly compared. Here we designed and validated a risk stratification model for progression-free survival (PFS) and overall ...
Cecelia Perkins +71 more
core +1 more source
Adult-onset mastocytosis in the skin is highly suggestive of systemic mastocytosis [PDF]
, 2014 Adult-onset urticaria pigmentosa/mastocytosis in the skin almost always persists throughout life. The prevalence of systemic mastocytosis in such patients is not precisely known. Bone marrow biopsies from 59 patients with mastocytosis in the skin and all
Flaig, Michael J. +9 more
core +2 more sources
Systemic mastocytosis in the elderly [PDF]
American Journal of Hematology, 2013 “Later onset” of systemic mastocytosis (SM) has been associated with a poorer prognosis. We examined clinical and laboratory findings, associated disorders, and survival in an older mastocytosis population. After receiving Mayo Clinic Institutional Review Board approval, we identified 42 patients aged 70 years and older at the time of diagnosis of SM ...
Joseph H, Butterfield +1 more
openaire +2 more sources