Results 41 to 50 of about 61,997 (154)

Co-operating STAT5 and AKT signaling pathways in chronic myeloid leukemia and mastocytosis: possible new targets of therapy

Haematologica, 2014
Chronic myeloid leukemia and systemic mastocytosis are myeloid neoplasms sharing a number of pathogenetic and clinical features. In both conditions, an aberrantly activated oncoprotein with tyrosine kinase activity, namely BCR-ABL1 in chronic myeloid ...
Siham Bibi, Melis Dilara Arslanhan, Florent Langenfeld, Sylvie Jeanningros, Sabine Cerny-Reiterer, Emir Hadzijusufovic, Luba Tchertanov, Richard Moriggl, Peter Valent, Michel Arock   +9 more
doaj   +1 more source

Mast Cell Leukemia: Review of a Rare Disease and Case Report of Prolonged Survival after Allogeneic Stem Cell Transplant

Human Pathology: Case Reports, 2017
Mast cell leukemia is a rare and aggressive form of mastocytosis characterized by >20% mast cells found in the bone marrow aspirates of patients with signs of systemic mastocytosis-related organ damage.
James Bauer, MD, PhD, Walter Longo, MD, David Yang, MD   +2 more
doaj   +1 more source

Mastocytosis: One Word for Different Diseases

Oncology and Therapy, 2018
Mastocytosis is a neoplastic disease originating from tissue infiltration by transformed mast cells. The diagnosis requires a high grade of suspicion due to the large variety of presenting symptoms. The World Health Organization classification recognizes
Marianna Criscuolo, Luana Fianchi, Alessio M. E. Maraglino, Livio Pagano   +3 more
doaj   +1 more source

Systemic Mastocytosis [PDF]

, 2020
Kristen Gonter-Aubin, Andrew Kuykendall
  +5 more sources

Systemic Mastocytosis with Smoldering Multiple Myeloma: Report of a Case

Case Reports in Oncological Medicine, 2016
Systemic mastocytosis (SM) is a disease characterized by a clonal infiltration of mast cells affecting various tissues of the body. It is grouped into six different subtypes according to the World Health Organization classification. It is called indolent
Sassine Ghanem, Gwenalyn Garcia, Liu Ying, Matthew Hurford, Marcel Odaimi   +4 more
doaj   +1 more source

Indolent systemic mastocytosis limited to the bone: a case report and review of the literature

São Paulo Medical Journal
CONTEXT Systemic mastocytosis is defined as a clonal disorder of mast cells and their precursor cells and is currently classified as a myeloproliferative neoplasm.
Pedro Pinto-Lopes, Francisco Adao Fonseca, Roberto Silva, Pedro von Hafe, Elsa Fonseca   +4 more
doaj   +1 more source

Recurrent prosthetic mitral valve thrombosis: The first report of an unusual feature of systemic mastocytosis, a case report and review of the literature. [PDF]

Caspian Journal of Internal Medicine
Background: Mastocytosis is a systemic disease involving the clonal expansion of mast cells in multiple organs. Given that immune system overreaction and excessive histamine release are among the most prominent events in mastocytosis, the incidence of ...
Amirhossein Akbarzadehpasha, Zahra Lotfi, Razieh Omidvar, Azadeh Goodarzi, Saeid Hosseini, Afsaneh Sadeghzadeh Bazargan, Kambiz Kamyab Hesari   +6 more
doaj  

Systemic Mastocytosis Associated with Splenic Marginal Zone Lymphoma with Villous Lymphocytes

Dermatology Research and Practice, 2011
The development of a second haematological disease during the course of systemic mastocytosis is a well-known phenomenon. In most of the cases, they consist of myelodysplasia or myeloproliferative disorders.
R. Fernández-Torres, M. M. Verea, A. Álvarez, P. Torres, E. Fonseca   +4 more
doaj   +1 more source

Assessment of skin manifestations under mastocytosis in adults and their associations with symptoms, level of tryptase and subtype of the disease

Лечащий Врач, 2021
Clinical features of 30 adult patients suffering from mastocytosis with skin lesion were compared with the duration of the disease, severity of skin and systemic symptoms, involvement of the internals in the pathologic process, level of tryptase in the ...
N. P. Teplyuk, P. M. Pyatilova
doaj  

Systemic mastocytosis associated with chronic myelomonocytic leukemia and xanthogranuloma

Dermatology Practical & Conceptual, 2012
A patient with a history of non-diagnostic bone marrow biopsies presented with a red to brown maculopapular rash on the back. Biopsies confirmed multiple xanthogranulomas as well as a mastocytosis.
Philipp Tschandl, Leonhard Müllauer, Harald Kittler   +2 more
doaj