Results 81 to 90 of about 65,460 (210)
A 64-year-old man was admitted to the hematology ward due to neutropenia and thrombocytopenia. The only symptom in the month preceding his admission, was significant weight loss.
Rontogianni, Dimitra +5 more
core +1 more source
A Case for Anti‐IgE Vaccination
ABSTRACT Immunoglobulin E (IgE) plays a central role in allergic diseases by binding to the high‐affinity receptor FcεRI on mast cells and basophils, where allergen‐induced crosslinking triggers potent inflammatory responses. Various mechanisms by which IgE responses are generated and functionally regulated remain elusive despite many years of research.
Paul Engeroff +3 more
wiley +1 more source
BackgroundStinging Hymenoptera can induce fatal anaphylaxis, especially in patients with systemic mastocytosis. Fire ants, Solenopsis invicta and S. richteri, from South America have recently colonized three continents.
Jeremy C. McMurray +11 more
doaj +1 more source
Mutational status in patients with systemic mastocytosis.
ISM, indolent systemic mastocytosis; SM-AHNMD, Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease; wt, wild-type.*UPD2pterp13.1 (homozygous DNMT3A mutation).†UPD4q12qter (homozygous KIT and TET2 mutation).‡Patients ...
Valeria Visconte (143692) +18 more
core +1 more source
Diagnosing Systemic Mastocytosis: State of the Art
ABSTRACT With the advent of effective multikinase and selective tyrosine kinase inhibitors in systemic mastocytosis, diagnosing this rare disease has been critical to improving patient morbidity and mortality. This state‐of‐the‐art review interprets the international diagnostic criteria, including differences between the WHO 5th edition classification ...
Anton Rets, Tracy I. George
wiley +1 more source
Enhanced PIEZO1 expression in mast cells of mastocytosis skin lesions: Relevance to Darier's sign
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Yoshiaki Kobayashi +9 more
wiley +1 more source
Abstract Pediatric anaphylaxis is a rapidly evolving and potentially fatal allergic reaction whose incidence is increasing worldwide, particularly among young children. Despite international guidelines identifying intramuscular epinephrine as the first‐line, life‐saving treatment, significant health inequities persist in the prevention, recognition ...
Carolina Grella +11 more
wiley +1 more source
Background. Mastocytosis is a very rare disease with various manifestations, based on abnormal clonal proliferation of mast cells in organs and tissues, such as: skin, bone marrow, lymph nodes, liver, spleen, and gastrointestinal tract. The diagnosis can
Timur T. Valiev +6 more
doaj +1 more source
Clinical potential of midostaurin in advanced systemic mastocytosis
Marie Olivia Chandesris,1–3 Gandhi Damaj,1,4 Olivier Lortholary,1,3,5 Olivier Hermine1–3,6 On behalf of the CEREMAST study group 1French Reference Center for Mastocytosis (CEREMAST), 2Department of Hematology, Necker Children’s Hospital,
Hermine O +3 more
core
SYSTEMIC MASTOCYTOSIS ASSOCIATED WITH MINIMAL CHANGE DISEASE
Systemic Mastocytosis (SM) has not previously been reported in association with minimal change disease (MCD). Mastocytosis is a rare myeloproliferative disease that is characterised by uncontrolled proliferation of aberrant mast cells. This can lead to a
Sophia Otto +3 more
core +1 more source

