Results 41 to 50 of about 77,151 (268)
Clinical effectiveness of hymenoptera venom immunotherapy [PDF]
Treatment failure during venom immunotherapy (VIT) may be associated with a variety of risk factors. Our aim was to evaluate the association of baseline serum tryptase concentration (BTC) and of other parameters with the frequency of VIT failure during ...
Aberer, Werner +21 more
core +1 more source
Background: Anaphylactic reactions are a well-known feature of mastocytosis, particularly in relation to hymenoptera venom stings. Although data on the frequency of drug hypersensitivity reactions is limited in mastocytosis, it is hypothesized that these
Jesper Jarkvist, Theo Gülen
doaj +1 more source
A role for eosinophils in the intestinal immunity against infective Ascaris suum larvae [PDF]
The aim of this study was to explore the mechanisms of resistance against invading Ascaris suum larvae in pigs. Pigs received a low dose of 100 A. suum eggs daily for 14 weeks.
Chiers, Koen +6 more
core +4 more sources
PD-1 Regulates the Growth of Human Mastocytosis Cells
Background: Programmed death-1 (PD-1) is a marker for human neoplastic T cells. Here, we evaluated whether or not PD-1 was also a marker for human mastocytosis, and explored the role of PD-1 in human mastocytosis cells.
Tatsuki R. Kataoka +9 more
doaj +1 more source
Mastocytosis: a mutated KIT receptor induced myeloproliferative disorder [PDF]
Although more than 90% systemic mastocytosis (SM) patients express gain of function mutations in the KIT receptor, recent next generation sequencing has revealed the presence of several additional genetic and epigenetic mutations in a subset of these ...
Chatterjee, Anindya +2 more
core +2 more sources
Kit receptor tyrosine kinase dysregulations in feline splenic mast cell tumours [PDF]
This study investigated Ki t receptor dysregulations (cytoplasmic immunohistochemical expression and/or c-KIT mutations) in cats a\ufb00ected with splenic mast cell tumours. Twenty-two cats were included.
Amagai +32 more
core +1 more source
Objective: Mastocytosis is a complex disorder affecting various organs. The diagnostic workup can be challenging and requires a multidisciplinary approach including the use of uncommon tests.
Polina Pyatilova, MD +8 more
doaj +1 more source
Receptor tyrosine kinase and p16/CDKN2 expression in a case of tripe palms associated with non-small-cell lung cancer [PDF]
Background: Tripe palms is a descriptive term for a cutaneous paraneoplastic keratoderma. Tripe palms are frequently associated with gastric and pulmonary carcinoma. The pathogenetic mechanism remains unknown.
Bezold, G. +5 more
core +1 more source
Biochemical markers predictive for bone marrow involvement in systemic mastocytosis
Systemic mastocytosis is characterized by bone marrow involvement, which requires a bone marrow biopsy for diagnostic work-up. We questioned whether bone marrow involvement could be predicted using biochemical markers.
Marjolein L. Donker +7 more
doaj +1 more source
Mastocytosis is a rare disorder affecting both children and adults by gathering of functionally defective mast cells in the body’s tissues. The World Health Organization (WHO) classified mastocytosis into cutaneous mastocytosis, systemic mastocytosis (SM)
Ing Chen +4 more
doaj +1 more source

