The Basophil Activation Test Is Not a Useful Screening Tool for Hymenoptera Venom-Related Anaphylaxis in Patients with Systemic Mastocytosis [PDF]
Background: Systemic mastocytosis (SM) patients are at a high risk for anaphylaxis, with Hymenoptera as the main culprit. A screening instrument to identify which patients are sensitized to Hymenoptera before they experience anaphylaxis would therefore ...
Daele, P.L.A. (Paul) van +4 more
core +1 more source
NCCN Guidelines® Insights: Systemic Mastocytosis, Version 3.2024.
Mastocytosis is a heterogeneous group of disorders comprising cutaneous mastocytosis, systemic mastocytosis, and mast cell sarcoma. It is associated with a variety of symptoms related to the release of mast cell mediators and mast cell tissue ...
J. Gotlib +33 more
semanticscholar +1 more source
CD30 as a Target Molecule in the Diagnosis and Therapy of Lymphomas
ABSTRACT The tumor necrosis factor (TNF)‐receptor superfamily 8 receptor CD30 molecule is expressed in all tumor cells of Hodgkin lymphoma and anaplastic large cell lymphoma but is only weakly expressed in a small subset of large lymphoid cells in normal peripheral lymphoid tissues.
Harald Stein, Brunangelo Falini
wiley +1 more source
Drug hypersensitivity reactions and allergy in patients with mastocytosis
Mastocytosis is a rare myeloproliferative disease caused by excessive proliferation and accumulation of mast cells in the skin and internal organs. The most common variant of mastocytosis in children is cutaneous mastocytosis.
Justyna H. Czarny +7 more
doaj +1 more source
Comprehensive mastocytosis data analysis from a single center
Mastocytosis is a very rare disorder and is divided into three prognostically distinct variants by World Health Organization: Cutaneous mastocytosis (CM), systemic mastocytosis (SM), and mast cell sarcoma or localized mast cell (MC) tumors.
Tarık Onur Tiryaki +11 more
doaj +1 more source
Bone Marrow Mastocytosis: A Diagnostic Challenge
Bone marrow mastocytosis (BMM) represents a provisional, indolent subvariant of systemic mastocytosis (SM). Utilizing WHO criteria, BMM requires bone marrow (BM) involvement and the absence of mastocytosis skin lesions.
R. Zanotti +4 more
semanticscholar +1 more source
Genomics and Histopathology in Interstitial Cystitis/Bladder Pain Syndrome
ABSTRACT Aims In April of 2025, a Global Consensus meeting on IC/BPS was held in Winston‐Salem, NC. The goal of this meeting was to establish global consensus in diagnostic criteria, phenotyping, treatment outcome assessment, and possible etiopathology in interstitial cystitis/bladder pain syndrome (IC/BPS).
Hannah Ruetten +4 more
wiley +1 more source
Difficulties in diagnosis and management of mastocytosis in clinical practice and role of patients' associations [PDF]
Mastocytosis is a heterogeneous group of disorders characterized by abnormal expansion and accumulation of mast cells in one or more organs. It is a rare disease, with uncertain prevalence in many countries. The diagnosis and management of rare diseases,
Polliana Mihaela LERU, Dumitru MATEI
doaj +1 more source
An adolescent girl with signs and symptoms of anaphylaxis and negative immunologic workup: a case report. [PDF]
BackgroundThe increasing incidence of allergies and allergic reactions among children and adults has become a major public health concern. The etiology of allergic reactions can often be confirmed based on a detailed history and supportive testing ...
Bauer, Maureen +4 more
core
Vascular endothelial growth factors and angiopoietins as new players in mastocytosis
Mastocytosis is a disorder characterized by the abnormal proliferation and/or accumulation of mast cells in different organs. More than 90% of patients with systemic mastocytosis have a gain-of-function mutation in codon 816 of the KIT receptor on mast ...
Simone Marcella +13 more
semanticscholar +1 more source

