Results 71 to 80 of about 1,484 (164)

Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay.

PLoS ONE, 2013
Adiponectin, the adipose-derived hormone, plays an important role in the suppression of metabolic disorders that can result in type 2 diabetes, obesity, and atherosclerosis.
Yiyi Sun, Zhihe Zang, Ling Zhong, Min Wu, Qing Su, Xiurong Gao, Wang Zan, Dong Lin, Yan Zhao, Zhonglin Zhang   +9 more
doaj   +1 more source

Antioxidant Potential of Polyphenolic Compounds, Sources, Extraction, Purification and Characterization Techniques: A Focused Review

Food Science &Nutrition, Volume 13, Issue 12, December 2025.
This review highlights the antioxidant potential of polyphenolic compounds derived from diverse plant sources. It outlines extraction and purification methods, advanced spectroscopic and chromatographic characterization techniques, and underlying antioxidant mechanisms such as radical scavenging, metal chelation, and signalling modulation.
Zubair Ahmad, Abdur Rauf, Ilkay Erdogan Orhan, Mohammad S. Mubarak, Zuneera Akram, Md. Rezaul Islam, Muhammad Imran, Zehra Edis, Benod Kumar Kondapavuluri, Lakshmi Thangavelu, Muthu Thiruvengadam   +10 more
wiley   +1 more source

Matairesinol Nanoparticles Restore Chemosensitivity and Suppress Colorectal Cancer Progression in Preclinical Models: Role of Lipid Metabolism Reprogramming

Oncogenic-driven lipogenic metabolism is a common hallmark of colorectal cancer (CRC) progression. Therefore, there is an urgent need to develop novel therapeutic strategies for metabolic reprogramming.
Shenshen Wu (2811523), Michael Aschner (182839), Jiajia Wang (157207), Rui Chen (95310), Michela Relucenti (305624), Zan Fu (5151308), Giuseppe Familiari (305611), Xiaobo Li (118828), Hanqing Chen (680607)   +8 more
core   +1 more source

Interaction of Carthamus tinctorius lignan arctigenin with the binding site of tryptophan-degrading enzyme indoleamine 2,3-dioxygenase [PDF]

, 2013
Mediterranean Carthamus tinctorius (Safflower) is used for treatment of inflammatory conditions and neuropsychiatric disorders. Recently C. tinctorius lignans arctigenin and trachelogenin but not matairesinol were described to interfere with the activity
Schwaiger, Stefan, Stuppner, Hermann, Daniela Schuster, Temml, Veronika, Fuchs, Dietmar, Veronika Temml, Schuster, Daniela, Stefan Schwaiger, Susanne Kuehnl, Dietmar Fuchs, Hermann Stuppner, Kuehnl, Susanne   +11 more
core   +1 more source

Active Components with Inhibitory Activities on IFN-γ/STAT1 and IL-6/STAT3 Signaling Pathways from Caulis Trachelospermi

Molecules, 2014
Initial investigation for new active herbal extract with inhibiting activity on JAK/STAT signaling pathway revealed that the extract of Caulis Trachelospermi, which was separated by 80% alcohol extraction and subsequent HP-20 macroporous resin column ...
Xiao-Ting Liu, Zhe-Xing Wang, Yu Yang, Lin Wang, Ruo-Feng Sun, Yi-Min Zhao, Neng-Jiang Yu   +6 more
doaj   +1 more source

Functional Foods Enriched With Bioactive Compounds: Therapeutic Potential and Technological Innovations

Food Science &Nutrition, Volume 13, Issue 10, October 2025.
Functional foods enriched with bioactive compounds such as polyphenols, carotenoids, omega‐3 fatty acids, and probiotics provide therapeutic benefits through antioxidant, anti‐inflammatory, and gut‐modulating mechanisms. Advances in biotechnology and AI have improved screening, formulation, and delivery of these compounds in diverse food matrices ...
Zargull Arshad, Shafa Shahid, Ammarah Hasnain, Esha Yaseen, Mehdi Rahimi   +4 more
wiley   +1 more source

Optimizing Health and Sustainability: Innovations in Harnessing Phytochemicals for Functional Foods

Food Science &Nutrition, Volume 13, Issue 9, September 2025.
Advances in phytochemical extraction and integration into functional foods are reviewed. Phytochemicals help address cardiovascular, metabolic, and cognitive health challenges. Circular food systems and waste valorization enhance sustainable use of phytochemicals.
Faiyaz Ahmed, Sammra Maqsood, Md Faruque Ahmad, Ahmadullah Zahir   +3 more
wiley   +1 more source

Studies on the biosynthesis of podophyllotoxin:synthesis of labelled yatein and matairesinol, two potential precursors of podophyllotoxin

, 2009
Podophyllotoxin, a naturally occurring lignan isolated from several species of Podophyllum, is used as a precursor to the clinical chemotherapeutic agents teniposide and etoposide.
Neidigh, Kurt Alan
core  

Untersuchungen zur Wirkung von vier verschiedenen kommerziellen Lignanen auf humane Mammaepithelzellen [PDF]

, 2019
Die Lignane Secoisolariciresinol, Matairesinol, Enterodiol und Enterolacton zeigten eine konzentrationsabhängige antiproliferative Wirkung auf humane Mammaepithelzellen mit unterschiedlicher Dignität und Rezeptorstatus in-vitro.
Solf, Friederike Christiane (gnd: 1222678780)
core   +1 more source

Centaurea lycaonica Extracts Induce Apoptosis in HeLa Human Cervical Cancer Cells via Bax/Bcl‐2 Modulation and Caspase Activation: An LC‐HRMS‐Based Study

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
This study highlights the pharmacological mechanisms of dichloromethane (CHD) and methanol (CHM) extracts of Centaurea lycaonica Boiss. & Heldr. herba as the induction of apoptosis on HeLa cells. Apoptotic properties of CHD and CHM are through suppression of Bcl‐2 and increase in Bax, caspase 9, and 3 activities on HeLa cells.
Ayşe Kübra Karaboğa Arslan, Safa Eminoğlu, Leyla Paşayeva, Nuh Mehmet Bozkurt, Osman Tugay   +4 more
wiley   +1 more source