Results 101 to 110 of about 2,631 (192)

VsMATE1-Mediated Citrate Efflux Is Involved in Al Resistance in Common Vetch (Vicia sativa L.)

Plants
Planting aluminum-tolerant legume green manure is a cost-effective and sustainable method to increase soil fertility as well as decrease Al toxicity in acidic soils.
Wenhui Yan, Jia Shi, Ling He, Zigang Hou, Zhenfei Guo, Haifeng Zhu   +5 more
doaj   +1 more source

ePosters Virtual

European Journal of Neurology, Volume 33, Issue S1, June 2026.
wiley   +1 more source

Pharmacogenetics of Oral Antidiabetic Drugs

International Journal of Endocrinology, 2013
Oral antidiabetic drugs (OADs) are used for more than a half-century in the treatment of type 2 diabetes. Only in the last five years, intensive research has been conducted in the pharmacogenetics of these drugs based mainly on the retrospective register
Matthijs L. Becker, Ewan R. Pearson, Ivan Tkáč   +2 more
doaj   +1 more source

Identification and functional characterization of genetic variations in the promoter of MATE1 and MATE2-K in Koreans

, 2013
간과 신장은 약물과 다른 생체 이물들을 체외로 배출시키는데 중요한 역할을 한다. 사람의 MATE1 수송체는 간세포의 모세담즙관막에 발현되어 있으면서 OCT1과 함께 많은 양이온계 약물과 기질물질들을 담즙을 통해 배설시킨다. 또한 MATE1은 신장의 근위세뇨관 꼭지면세포막에 주로 발현되어 있으면서 기저측면막 수송체인 OCT2와 함께 유기 양이온계 물질들을 배출시킨다.
김경희
core  

Expression of SLC transporters in melanoma cell lines and characterization of MATE1 and OCT1 in their function as transporters of antineoplastic agents

, 2011
Ein Problem der heutigen Krebstherapie ist die geringe Ansprechrate bei der Behandlung mit Zytostatika. Ein Teil dieser Chemoresistenz beruht auf der geringen Akkumulation von Zytostatikamolekülen in ...
Grottker, Julia
core   +1 more source

Transcriptome Analysis of mfs2-Defective Penicillium digitatum Mutant to Reveal Importance of Pdmfs2 in Developing Fungal Prochloraz Resistance

Microorganisms
Demethylation inhibitors (DMIs), including prochloraz, are popular fungicides to control citrus postharvest pathogens such as Penicillium digitatum (green mold). However, many P.
Rongrong Cuan, Shaoting Liu, Chuanyou Zhou, Shengqiang Wang, Yongliang Zheng, Yongze Yuan   +5 more
doaj   +1 more source

Effect of Ro 31–8220 on OCT2, MATE1 and MATE2-K activities.

, 2015
(A) HEK-OCT2 cells were incubated with 40 μM [14C]-TEA for 5 min at 37°C and pH = 7.4, in the presence or absence of (Left) 500 μM amitriptyline or 5 μM Ro 31–8220, or of (Right) various concentrations (from 0.01 to 10 μM) of Ro 31–8220. After washing by
Yannick Parmentier (835472), Olivier Fardel (226470), Arnaud Bruyere (835469), Abdullah Mayati (835468), Elodie Jouan (710326), Claire Denizot (835471), Amélie Moreau (835470)   +6 more
core   +1 more source

Metabolic basis of solute carrier transporters in treatment of type 2 diabetes mellitus

Acta Pharmaceutica Sinica B
Solute carriers (SLCs) constitute the largest superfamily of membrane transporter proteins. These transporters, present in various SLC families, play a vital role in energy metabolism by facilitating the transport of diverse substances, including glucose,
Jiamei Le, Yilong Chen, Wei Yang, Ligong Chen, Jianping Ye   +4 more
doaj   +1 more source

Molecular Mechanism of Renal Tubular Secretion of the Antimalarial Drug Chloroquine

, 2011
The antimalarial drug chloroquine is eliminated to a significant extent by renal tubular secretion. The molecular mechanism of renal chloroquine secretion remains unknown.
Fabian Müller, Jörg König, Ingrid Schmidt, Renke Maas, Hartmut Glaeser, Martin F. Fromm, Oliver Zolk   +6 more
core   +1 more source

The role of genetic variants in the prediction of hearing loss due to cisplatin chemoradiotherapy

Cancer Medicine
Background Concomitant high‐dose cisplatin with radiotherapy is commonly used for treating head and neck squamous cell carcinoma (HNSCC). Cisplatin, often used with radiotherapy, is known for causing irreversible sensorineural hearing loss, with ...
Charlotte W. Duinkerken, Sabrina Chiodo, Katrina Hueniken, Michael Hauptmann, Katarzyna Jóźwiak, Dangxiao Cheng, Andrew Hope, Geoffrey Liu, Charlotte L. Zuur   +8 more
doaj   +1 more source