Results 181 to 190 of about 2,631 (192)

P246 - Nephrotoxicity in MATE1, MATE2K and MATE1/2K knockout cell lines following treatment with cisplatin using the mimetas 3D organoplate platform

Drug Metabolism and Pharmacokinetics, 2020
Toni Steiner, David Thompson
openaire   +1 more source

Amiloride is a suitable fluorescent substrate for the study of the drug transporter human multidrug and toxin extrusion 1 (MATE1)

Biochemical and Biophysical Research Communications, 2022
Tomohiro Nabekura
exaly  

Fampridine is a substrate and inhibitor of human OCT2, but not MATE1 and MATE2K

Drug Metabolism and Pharmacokinetics, 2018
Christopher Rowbottom, Carri Boiselle, Lawrence Gan, Tonika Bohnert, Guangqing Xiao   +4 more
openaire   +1 more source

Metformin selectively inhibits metastatic colorectal cancer with the KRAS mutation by intracellular accumulation through silencing MATE1

Proceedings of the National Academy of Sciences of the United States of America, 2020
Jinye Xie, Liangping Xia, Wenzhuo He
exaly  

The L125F MATE1 variant enriched in populations of Amerindian origin is associated with increased plasma levels of metformin and lactate

Biomedicine and Pharmacotherapy, 2021
Angelica Martinez-Hernandez, Cecilia Contreras-Cubas, Humberto García-Ortiz   +2 more
exaly  

Molecular Cloning, Functional Characterization and Tissue Distribution of Rat H+/Organic Cation Antiporter MATE1

Pharmaceutical Research, 2006
Satohiro Masuda, Jun-Ichi Asaka, Masahiro Tsuda   +2 more
exaly  

In Vitro Inhibition of Renal OCT2 and MATE1 Secretion by Antiemetic Drugs

Journal of the American Society of Nephrology, 2020
Blessy George, Xia Wen, Edgar A. Jaimes, Melanie S. Joy, Lauren Aleksunes   +4 more
openaire   +1 more source

Identification of multidrug and toxin extrusion (MATE1 and MATE2-K) variants with complete loss of transport activity

Journal of Human Genetics, 2009
Ken Ogasawara, Toshiya Katsura, Ken-Ichi Inui   +2 more
exaly  

Interplay of the Organic Cation Transporters OCT1 and OCT2 with the Apically Localized Export Protein MATE1 for the Polarized Transport of Trospium

Molecular Pharmaceutics, 2019
Birgit Deutsch, Ulrich Schwantes
exaly  

Importance of OCT2 and MATE1 for the Cimetidine–Metformin Interaction: Insights from Investigations of Polarized Transport in Single- And Double-Transfected MDCK Cells with a Focus on Perpetrator Disposition

Molecular Pharmaceutics, 2018
Fabian Müller, Jörg KÖNIG
exaly