Results 51 to 60 of about 2,631 (192)
Journal of Pharmacological Sciences, 2017 Previously, we reported that specific lower dose of sodium 2,3-dimercapto-1-propanesulfonic acid (DMPS) which is an antidote to heavy metal intoxication, inversely enhanced cisplatin (CDDP)-induced antitumor activity to S-180 cell-bearing mouse.
Yuka Yajima +6 more
doaj +1 more source
Pharmacological Research, 2023 Solute carrier (SLC) transport proteins are fundamental for the translocation of endogenous compounds and drugs across membranes, thus playing a critical role in disease susceptibility and drug response.
Anne T. Nies +14 more
doaj +1 more source
, 2016 Multidrug and toxic compound extrusion transporter-1 (MATE1) is a quercetin transporter. We examined the associations of quercetin intake and polymorphism of MATE1 in relation to metabolic syndrome (MetS) in Hallym Aging Study.
Park, Hye Won +6 more
core +1 more source
Pharmaceutics, 2019 We aimed to assess the potential herb–drug interactions between Korean red ginseng extract (RGE) and metformin in rats in terms of the modulation of metformin transporters, such as organic cation transporter (Oct), multiple toxin and extrusion ...
Sojeong Jin +5 more
doaj +1 more source
Japanese Women's Attitudes Toward Learning Languages Other Than English in the Era of Global English
International Journal of Applied Linguistics, EarlyView.ABSTRACT This study on female Japanese learners of the Korean language is situated in the centuries‐long anti‐Korean sentiments in Japan, the global popularity of the Korean Wave, particularly among women, and the essentialized image of socially marginalized young Japanese women who study English with romantic desires for Western men.
Yoko Kobayashi
wiley +1 more source
Contribution of MATE1 to Dofetilide-Induced Proarrhythmia
, 2022 Dofetilide is a rapid delayed rectifier potassium current inhibitor widely used to prevent the recurrence of atrial fibrillation and flutter. The clinical use of this drug is associated with increases in QTc interval, which predisposes to ventricular ...
Huang, Kevin M +23 more
core
Impact of Viral Inflammation on the Expression of Renal Drug Transporters in Pregnant Rats
Pharmaceutics, 2019 Inflammation impacts the expression and function of drug transporters at term-gestation; however, the impact of inflammation on the expression of drug transporters at mid-gestation is largely unknown.
Navaz Karimian Pour +2 more
doaj +1 more source
Genetic polymorphisms of multidrug and toxin extrusion proteins (MATE1 and MATE2) in South Indian population [PDF]
BioImpacts, 2017 Introduction: Drug transporters are key determinants of pharmacokinetic and pharmacodynamic profiles of certain drugs. SLC47A1 (MATE1) and SLC47A2 (MATE2) are major efflux transporters involved in the hepatic and renal excretion of many cationic drugs ...
Gerard Marshall Raj +4 more
doaj +1 more source
Physiological and anatomical determinants of placental drug transfer
The Journal of Physiology, EarlyView.Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 7, Page 2349-2363, July 2026.Abstract Aims This work assessed the pharmacokinetics (PK), safety and tolerability of glasmacinal (EP395, an oral anti‐inflammatory macrolide with negligible antimicrobial activity in development for COPD treatment) in two healthy participant trials: ‘first‐in‐human’ (FIH) and ‘drug–drug‐interaction’ (DDI).
Dave Singh +5 more
wiley +1 more source