Results 111 to 120 of about 3,143,235 (349)

Optimization of Multiple Response Using Taguchi-WPCA in ST 60 Tool Steel Turning Process with Minimum Quantity Cooling Lubrication (MQCL) Method [PDF]

, 2018
A research was conducted for the optimization of the turning process st 60 tool steel with multiple performance characteristics based on the orthogonal array with Taguchi-WPCA method.
Choiron, M. A. (Moch), Pamuji, D. R. (Dian), Rohman, A. (Abdul), Sonief, A. A. (Achmad), Wahid, M. A. (Muhammad)   +4 more
core   +2 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Electro-discharge machining of alumina: Investigation of material removal rate and surface roughness

Journal of Mechanical Engineering and Sciences, 2017
Alumina is a non-conductive ceramic material which can meet the high demand of industrial applications due to its excellent physical and chemical properties.
M.Y. Ali, M.A. Moudood, M.A. Maleque, M. Hazza, E. Y. T. Adesta   +4 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Experimental Investigations into Electro Discharge Machining of NiTi Shape Memory Alloys using Rotational Tool

International Journal of Electrochemical Science, 2013
Electro discharge machining is one of the nontraditional machining procedures, which is used for machining the high strength and hardness materials. In this article, the impact of rotational tool and input parameters include; pulse current, pulse on time,
Saeed Daneshmand, Ehsan Farahmand Kahrizi, Ali Akbar Lotfi Neyestanak, Mehrdad Mortazavi Ghahi   +3 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Machining strategy development in 5-axis milling operations using process models [PDF]

, 2010
Increased productivity and part quality can be achieved by selecting machining strategies and conditions properly. At one extreme very high speed and feed rate with small depth of cut can be used for high productivity whereas deep cuts accompanied with ...
Budak, Erhan, Murtezaoglu, Yavuz, Murtezaoğlu, Yavuz, Ozkirimli, Omer Mehmet, Ozturk, Erdem, Tunc, Taner L., Tunç, Taner L., Özkırımlı, Ömer Mehmet, Öztürk, Erdem   +8 more
core  

Effect of the material properties on removal rate in SEDM

Journal of The Japan Society of Electrical Machining Engineers, 2011
Electric discharge machining has been widely used in making the arbitrary shapes for various metallic materials, and appropriate conditions for such machining have been selected mostly by trial machining in actual processes. However, the removal rate are depends on the fundamental thermal properties of the materials used.
Masahide YAMASHITA, Tomoo KITAMURA, Ken YAMASHITA, Yasushi FUKUZAWA   +3 more
openaire   +1 more source

Erosion of iron-chromium alloys by glass particles [PDF]

The material loss upon erosion was measured for several iron-chromium alloys. Two types of erodent material were used: spherical glass beads and sharp particles of crushed glass.
Buckley, D. H., Salik, J.
core   +1 more source

Investigation of the effects of machining parameters on material removal rate in abrasive waterjet turning [PDF]

, 2014
The effects of the main operational machining parameters on the material removal rate (MRR) in abrasive waterjet turning (AWJT) are presented in this paper using a statistical approach.
Annoni, Massimiliano, Zohoor, Mehdi, Zohourkari, Iman   +2 more
core   +2 more sources