Results 101 to 110 of about 3,143,235 (349)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Laser balancing system for high material removal rates [PDF]
A laser technique to remove material in excess of 10 mg/sec from a spinning rotor is described. This material removal rate is 20 times greater than previously reported for a surface speed of 30 m/sec. Material removal enhancement was achieved by steering
Georgalas, G. +2 more
core +1 more source
A review on the rotary ultrasonic machining of advanced ceramics [PDF]
Advanced ceramics are likely candidates for many industrial applications due to their superior properties. However, their high machining costs lead to limited applications.
Hamzah, Esah, Khoo, C. Y., Sudin, Izman
core
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
In this research, a novel aluminum alloy and metal matrix composite was designed and developed for self healing purpose. Tin at varying weight percentages (5, 10, 15 & 20 wt%) was alloyed into aluminum along with other alloying elements to form a new set
T. Thankachan +7 more
semanticscholar +1 more source
Mechanics,Mechanisms and Modeling of the Chemical Mechanical Polishing Process [PDF]
The Chemical Mechanical polishing (CMP) process is now widely employed in the Integrated Circuit Fabrication. However, due to the complexity of process parameters on the material removal rate (MRR), mechanism of material removal and pattern effect are ...
Chun, Jung-Hoon +3 more
core
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
MATERIAL REMOVAL RATE IN ELECTROCHEMICAL DISCHARGE MACHINING OF SMALL DIAMETER HOLES
Electrochemical discharge machining method is based on the material removal from workpiece as a consequence of simultaneous development of electrical discharges between the electrodes and of the electrochemical reactions between the work liquid and ...
Margareta Coteata +4 more
doaj
STUDY OF POLISHING AISI 316L WITH STRUCTURED ABRASIVE [PDF]
Finishing process like polishing is usually used to obtain high quality mechanical surface characteristics such as texture and roughness. These operations are mainly handmade and need highly trained operators thus limiting their repeatability and ...
François GOOSSENS +2 more
doaj

