Results 101 to 110 of about 13,024,848 (326)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

The kinetics and mechanisms of destabilisation and aggregation of microcolloidal iron and associated phosphate during simulated estuarine mixing

, 1999
The removal of iron from the <0.45µm fraction of Tamar River water on addition of both calcium chloride solution and sea water was studied using a continuous autoanalytical system.
Hudson, Andrew Neil
core   +1 more source

Research on the relationship between acoustic emission signal and material removal rate during fixed abrasive lapping

Jin'gangshi yu moliao moju gongcheng, 2017
Due to passivation and wear, fixed abrasive lapping pad needs to be conditioned.Material removal rate is one of the characteristic indexes to judge the condition of the lapping pad.The relationship between acoustic emission signal and material removal ...
TONG Haocheng, LI Jun, GUO Taiyu, MING Shun, ZHU Yongwei, ZUO Dunwen   +5 more
doaj  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Estimation of material removal rate distribution in double-sided polishing of thick square workpiece considering workpiece attitude

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2019
A workpiece attitude during polishing process is known to affect material removal rate distribution, which is one of the most significant properties in polishing process.
Yohei HASHIMOTO, Tomoya SANO, Tatsuaki FURUMOTO, Akira HOSOKAWA   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

STUDY OF POLISHING AISI 316L WITH STRUCTURED ABRASIVE [PDF]

Annals: Series on engineering sciences (Academy of Romanian Scientists), 2015
Finishing process like polishing is usually used to obtain high quality mechanical surface characteristics such as texture and roughness. These operations are mainly handmade and need highly trained operators thus limiting their repeatability and ...
François GOOSSENS, Mehdi CHERIF, Olivier CAHUC   +2 more
doaj  

Investigation of material removal rate and surface roughness during wire electrical discharge machining (WEDM) of Inconel 625 super alloy by cryogenic treated tool electrode

, 2017
The present investigation focuses the effect of process parameters on material removal rate (MRR) and surface roughness (Ra) in wire electric discharge machining of Inconel 625.
A. Goyal
semanticscholar   +1 more source