Results 121 to 130 of about 13,024,848 (326)

The Effect of Voltage on Material Removal Rate in the ECM Process

Engineering, Technology & Applied Science Research
The development of machining processes, such as Electrochemical Machining (ECM), has improved manufacturing complex shapes and complicated materials. This research investigates the enhancement of the ECM process to achieve the highest quality of materials.
Nagham Ghanim Ghazi, Shukry Hammed Aghdeab, Asmaa Omar Basheer   +2 more
openaire   +1 more source

Comparison of hard machining procedures on material removal rate

, 2011
The economic efficiency of machining plays an important role in the comparison of alternative procedures in the field of precision manufacturing too. It is not easy to performthe comparison because of the dissimilarities of material removal processes and/
Kundrák, János, Molnár, Viktor
core   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Optimization of material removal rate for orthogonal cutting with vibration limits [PDF]

, 2012
Besides growing accuracy requirements for cut parts the maximisation of productivity has still an important role in industry. One possible measure for productivity in cutting processes is the material removal rate.
Stépán, Gábor, Janka Reith, Márta
core   +1 more source

Optimization and Modeling of Material Removal Rate in Wire-EDM of Silicon Particle Reinforced Al6061 Composite. [PDF]

Materials (Basel), 2021
Doreswamy D, Bongale AM, Piekarski M, Bongale A, Kumar S, Pimenov DY, Giasin K, Nadolny K.   +7 more
europepmc   +1 more source

A Wafer-Scale Material Removal Rate Model for Chemical Mechanical Planarization

, 2019
In this work, a new wafer-scale material removal rate (MRR) model is proposed to investigate the underlying removal mechanism of wafer surface in the chemical mechanical planarization (CMP) process.
Qin-Zhi Xu, Lan Chen, Jian-Yun Liu, He Cao   +3 more
semanticscholar   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Chemical mechanical polishing process parameters of 304 stainless steel

Jin'gangshi yu moliao moju gongcheng, 2016
When chemical-mechanically polishing 304 stainless steel,the effects of polishing pressure,polishing slurry flow rate,polishing speed and polishing time on the material removal rate and surface roughness are studied for better performance,lower cost and ...
LI Qing, CHEN Shaokun, PENG Yanan, QIN Hongquan, FU Sufang, SU Jianxiu   +5 more
doaj  

Statistical Modeling and Optimization of Ra and Mrr in Ultrasonic - Assisted of 90CrSi Steel Using Graphite Electrodes

Journal of Machine Engineering
This study investigates the modeling and single-objective optimization of surface roughness (Ra) and material removal rate (MRR) in electrical discharge machining (EDM) of external cylindrical surfaces of hardened 90CrSi tool steel. The machining process
Thanh Van Dinh, Quy Thu Le, Loi Tat Mai, Pi Ngoc Vu, Giang Ngoc Tran   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source