Results 91 to 100 of about 541,541 (258)

MUITI-OBJECTIVE OPTIMAZATION IN THE ELECTRICAL DISCHARGE MACHINING OF THE TA7 BASED ON BSO ALGORITHM

open access: yesJixie qiangdu, 2018
For the existing EDM machine,there is no specification of titanium alloy processing standard,the design center combination experiment,comprehensive consideration of no-load voltage,peak current,pulse width and pulse interval on TA7 EDM material removal ...
ZHANG LiXin, YANG Kang, LI YuXi
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Chemical mechanical polishing process parameters of 304 stainless steel

open access: yesJin'gangshi yu moliao moju gongcheng, 2016
When chemical-mechanically polishing 304 stainless steel,the effects of polishing pressure,polishing slurry flow rate,polishing speed and polishing time on the material removal rate and surface roughness are studied for better performance,lower cost and ...
LI Qing   +5 more
doaj  

Optimization and Modeling of Material Removal Rate in Wire-EDM of Silicon Particle Reinforced Al6061 Composite. [PDF]

open access: yesMaterials (Basel), 2021
Doreswamy D   +7 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Statistical Modeling and Optimization of Ra and Mrr in Ultrasonic - Assisted of 90CrSi Steel Using Graphite Electrodes

open access: yesJournal of Machine Engineering
This study investigates the modeling and single-objective optimization of surface roughness (Ra) and material removal rate (MRR) in electrical discharge machining (EDM) of external cylindrical surfaces of hardened 90CrSi tool steel. The machining process
Thanh Van Dinh   +4 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Vibration-assisted fixed abrasive polishing CaF2 crystal

open access: yesJin'gangshi yu moliao moju gongcheng, 2019
In order to improve polished surface quality of CaF2 crystal and increase material removal rate, the method of vibration-assisted fixed abrasive polishing of CaF2 crystal is proposed, which combined ultrasonic vibration with fixed abrasive polishing ...
HUANG Junyang   +5 more
doaj  

Effect of environmental friendly complexing agent and oxidant on CMP of aluminium alloy under low pressure

open access: yesJin'gangshi yu moliao moju gongcheng, 2020
Effects of oxidizer hydrogen peroxide(H2O2)and complexing agent chitosan oligosaccharide(COS)on material removal of aluminium alloy were investigated in alkaline slurry by using atomic force microscope(AFM), X-ray photoelectron spectroscopy(XPS)and ...
ZHU Yuguang   +4 more
doaj  

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