Results 71 to 80 of about 519,396 (299)
MATERIAL REMOVAL RATE IN ELECTROCHEMICAL DISCHARGE MACHINING OF SMALL DIAMETER HOLES
Nonconventional Technologies Review, 2015 Electrochemical discharge machining method is based on the material removal from workpiece as a consequence of simultaneous development of electrical discharges between the electrodes and of the electrochemical reactions between the work liquid and ...
Margareta Coteata +4 more
doaj
Electro-discharge machining of alumina: Investigation of material removal rate and surface roughness
Journal of Mechanical Engineering and Sciences, 2017 Alumina is a non-conductive ceramic material which can meet the high demand of industrial applications due to its excellent physical and chemical properties.
M.Y. Ali +4 more
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
STUDY OF POLISHING AISI 316L WITH STRUCTURED ABRASIVE [PDF]
Annals: Series on engineering sciences (Academy of Romanian Scientists), 2015 Finishing process like polishing is usually used to obtain high quality mechanical surface characteristics such as texture and roughness. These operations are mainly handmade and need highly trained operators thus limiting their repeatability and ...
François GOOSSENS +2 more
doaj
International Journal of Electrochemical Science, 2013 Electro discharge machining is one of the nontraditional machining procedures, which is used for machining the high strength and hardness materials. In this article, the impact of rotational tool and input parameters include; pulse current, pulse on time,
Saeed Daneshmand +3 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Modeling of Material Removal Rate and Surface Roughness Generated during Electro-Discharge Machining
Machines, 2019 This study reports on the numerical model development for the prediction of the material removal rate and surface roughness generated during electrical discharge machining (EDM).
Amin Razeghiyadaki +3 more
doaj +1 more source
Effect of the material properties on removal rate in SEDM
Journal of The Japan Society of Electrical Machining Engineers, 2011 Electric discharge machining has been widely used in making the arbitrary shapes for various metallic materials, and appropriate conditions for such machining have been selected mostly by trial machining in actual processes. However, the removal rate are depends on the fundamental thermal properties of the materials used.
Masahide YAMASHITA +3 more
openaire +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source