Results 101 to 110 of about 9,803,652 (406)

Maternal pre-pregnancy obesity and timing of puberty in sons and daughters: a population-based cohort study. [PDF]

, 2019
BackgroundIn many countries, an increased prevalence of obesity in pregnancy has coincided with a declining pubertal age. We aimed to explore the potential effect of maternal pre-pregnancy overweight and obesity on timing of puberty in sons and daughters.
Arah, Onyebuchi A, Brix, Nis, Ernst, Andreas, Henriksen, Tine Brink, Lauridsen, Lea LB, Nohr, Ellen A, Olsen, Jørn, Ramlau-Hansen, Cecilia Høst   +7 more
core   +2 more sources

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Effect of praziquantel treatment of Schistosoma mansoni during pregnancy on immune responses to schistosome antigens among the offspring: results of a randomised, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Offspring of women with schistosomiasis may exhibit immune responsiveness to schistosomes due to in utero sensitisation or trans-placental transfer of antibodies.
Cose, Stephen, Dunne, David W, Elliott, Alison M, Jones, Frances M, Kihembo, Macklyn, Mawa, Patrice A, Tweyongyere, Robert, Vennervald, Birgitte J, Webb, Emily L   +8 more
core   +5 more sources

Cerebral Palsy Among Term and Postterm Births

Pediatric Neurology Briefs, 2010
The relation of risk of cerebral palsy (CP) with gestational age among term and postterm births was investigated by researchers at the University of Bergen, Norway, and the Epidemiology Branch, NIH, Durham, NC, using Norway’s national health and ...
J Gordon Millichap
doaj   +1 more source

Maternal age and offspring developmental vulnerability at age five: A population-based cohort study of Australian children

PLoS Medicine, 2018
Background In recent decades, there has been a shift to later childbearing in high-income countries. There is limited large-scale evidence of the relationship between maternal age and child outcomes beyond the perinatal period.
K. Falster, M. Hanly, E. Banks, J. Lynch, G. Chambers, M. Brownell, S. Eades, Louisa R Jorm   +7 more
semanticscholar   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Risk Factors for Soil-Transmitted Helminth Infections during the First 3 Years of Life in the Tropics; Findings from a Birth Cohort. [PDF]

, 2014
Background: Soil-transmitted helminths (STH) infect more than 2 billion humans worldwide, causing significant morbidity in children. There are few data on the epidemiology and risk factors for infection in pre-school children. To investigate risk factors
A Amberbir, A Moncayo, Alejandro Rodriguez, C Figueiredo, C Steel, Carlos Sandoval, E Roy, F Bieri, I Guadalupe, I Malhotra, Irene Guadalupe, J Bukusuba, K Tanaka, M Albonico, M-E Sackey, Maria Elena Bottazzi, Martha Chico, N De Silva, Nely Broncano, P Cooper, P Cooper, P Hotez, P Lammie, P Muniz, Philip J. Cooper, R Mehta, R Oberhalman, S Kounnavong, S Williams-Blangero, S Williams-Blangero, Stefanie K. Menzies, T Cupedo, T Rajan, X Wang, Y Belyhun   +34 more
core   +11 more sources

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

Advanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li, Caiyun Ge, Wai Yen Yim, Hui Feng, Tiancheng Wu, Lu Chen, Qiaohua Xiong, Shumin Pan, Mei Wang, Huijun Chen, Yuanzhen Zhang, Hui Wang   +11 more
wiley   +1 more source

Factors Influencing Clinical Pregnancy Rates After Myomectomy Among Infertile Women: A Single Center Retrospective Study

Haseki Tıp Bülteni, 2018
Aim:To determine the clinical pregnancy rates after myomectomy in infertile women who underwent surgery due to myoma uteri and to investigate the clinical factors affecting outcomes.Methods:This retrospective single-centered study included infertile ...
Meryem Kuru Pekcan, Esra İşçi Bostancı, Aytekin Tokmak, Dilek Şahin Uygur, Yasemin Taşçı   +4 more
doaj   +1 more source

Association between maternal age and postpartum depression in Ardabil, Northwest of Iran: a cross-sectional study [PDF]

Patient Safety and Quality Improvement Journal
Introduction: Postpartum depression (PPD) is a mood disorder that negatively affects mother, child and family. This study aims to examine the association between maternal age and postpartum depression.
Afrouz Mardi, Sara Mahdad, Mehrnaz Mashoufi, Samira Shahbazzadeghan, Atefeh Shadman   +4 more
doaj   +1 more source