Results 71 to 80 of about 1,081,271 (339)

Fetal Akinesia/Hypokinesia and Arthrogryposis of Neuromuscular Origin: Etiologic Groups, Genetics, and Phenotypic Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive clinical and genetic characterization of individuals with arthrogryposis multiplex congenita (AMC), focusing on the distribution of genetic etiologies across the neuromuscular spectrum and comparing myogenic and neurogenic subtypes. Methods A total of 105 individuals with AMC were clinically and genetically
Florencia Pérez‐Vidarte, Berta Estévez‐Arias, Leslie Matalonga, Delia Yubero, Anna Codina, Carlos Ortez, Julita Medina, Lidia DeSena DeCabo, Laura Carrera‐García, Jesica Expósito‐Escudero, Cristina Jou, Eduardo F. Tizzano, Andres Nascimento, Daniel Natera‐de Benito   +13 more
wiley   +1 more source

An Ecological Risk Model for Early Childhood Anxiety: The Importance of Early Child Symptoms and Temperament [PDF]

, 2010
Childhood anxiety is impairing and associated with later emotional disorders. Studying risk factors for child anxiety may allow earlier identification of at-risk children for prevention efforts.
Briggs-Gowan, Margaret J., Carter, Alice S., Mian, Nicholas D., Wainwright, Laurel   +3 more
core   +3 more sources

Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Phenotype hospital, physician, and emergency department (ED) visits by diagnoses and specialty up to 29 years pre‐multiple sclerosis (MS) onset versus a matched population without MS. Methods We identified people with MS (PwMS) using population‐based administrative data from Ontario, Canada (1991–2020).
Helen Tremlett, Karl Everett, Colleen J. Maxwell, Feng Zhu, Ayesha Asaf, Ping Li, Kyla A. McKay, Yinshan Zhao, Ruth Ann Marrie   +8 more
wiley   +1 more source

Association of epidural analgesia during labor with neurodevelopment of children during the first three years: the Japan Environment and Children’s Study

Environmental Health and Preventive Medicine, 2022
Background: Epidural analgesia relives pain during labor. However, the long-term effects on neurodevelopment in children remain unclear. We explored associations between exposure to epidural analgesia during labor and childhood neurodevelopment during ...
Masayuki Shima, Narumi Tokuda, Hideki Hasunuma, Yoshiko Kobayashi, Hiroyuki Tanaka, Hideaki Sawai, Hiroaki Shibahara, Yasuhiro Takeshima, Munetaka Hirose, the Japan Environment and Children’s Study (JECS) Group   +9 more
doaj   +1 more source

Temporal effects of maternal psychological distress on child mental health problems at ages 3, 5, 7 and 11: analysis from the UK Millennium Cohort Study [PDF]

, 2019
Background: Psychological distress is common among women of childbearing age, and limited longitudinal research suggests prolonged exposure to maternal distress is linked to child mental health problems.
Chittleborough, Catherine, Deighton, Jessica, Hope, Steven, Law, Catherine, Lynch, John, Maika, Amelia, Micali, Nadia, Mittinty, Murthy, Pearce, Anna   +8 more
core   +1 more source

Molecular Screening of SCN1A‐Related Seizures in Children With Febrile Seizures: Diagnostic Yield and Variant Distribution

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SCN1A‐related seizures first present as febrile seizures (FS). Definitive features emerge later, making early diagnosis challenging. We evaluated the diagnostic yield and clinical characteristics of pathogenic SCN1A variants in FS, and analyzed the effect of variant characteristics on clinical phenotypes required for early ...
Jia Wang, Yang‐Yang Wang, Lin‐Yan Hu, Xiu‐Yu Shi, Wen He, Dan Sun, Baoguang Li, Xiaoming Liu, Sanqing Xu, Lijun Du, Chunhui Tang, Li‐Ping Zou   +11 more
wiley   +1 more source

Preterm Birth in Assisted Reproductive Technology: An Analysis of More Than 20,000 Singleton Newborns

Frontiers in Endocrinology, 2020
BackgroundSeveral studies have shown that newborns conceived through the ART procedures were associated with an increased incidence of preterm delivery compared to those conceived spontaneously regardless of the type of ART procedure.
Zhiqin Bu, Jiaxin Zhang, Linli Hu, Yingpu Sun   +3 more
doaj   +1 more source

Mitochondria, Maternal Inheritance, and Male Aging [PDF]

Current Biology, 2012
The maternal transmission of mitochondrial genomes invokes a sex-specific selective sieve, whereby mutations in mitochondrial DNA can only respond to selection acting directly on females. In theory, this enables male-harming mutations to accumulate in mitochondrial genomes when these same mutations are neutral, beneficial, or only slightly deleterious ...
Camus, M. Florencia, Clancy, David J., Dowling, Damian K.   +2 more
openaire   +3 more sources

Synchrony, complexity and directiveness in mothers\u27 interactions with infants pre- and post-cochlear implantation [PDF]

, 2014
This study investigated effects of profound hearing loss on mother–infant interactions before and after cochlear implantation with a focus on maternal synchrony, complexity, and directiveness.
Bergeson, Tonya R., Fagan, Mary K., Morris, Kourtney J.   +2 more
core   +1 more source

Early Intensive Versus Escalation Approach: Ten‐Year Impact on Disability in Relapsing Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the long‐term impact of early intensive treatment (EIT) versus escalation (ESC) strategies using high‐efficacy disease‐modifying therapies (HE‐DMTs) on disability progression in relapsing multiple sclerosis (RMS). Methods This observational study included 4878 RMS patients from the Italian Multiple Sclerosis Register ...
Pietro Iaffaldano, Giuseppe Lucisano, Tommaso Guerra, Francesca Caputo, Marta Simone, Massimiliano Copetti, Damiano Paolicelli, Emilio Portaccio, Francesco Patti, Paola Perini, Vincenzo Brescia Morra, Alessia Di Sapio, Matilde Inglese, Carlo Pozzilli, Giacomo Lus, Giuseppe Salemi, Erica Curti, Giovanna De Luca, Paola Valentino, Eleonora Cocco, Paola Cavalla, Carlo Avolio, Alessandra Lugaresi, Antonio Gallo, Pietro Annovazzi, Maria A. Rocca, Clara Grazia Chisari, Massimo Filippi, Maria Pia Amato, Maria Trojano, on behalf of the Italian MS Register, Beatrice Biolzi, Daniele Dell’Anna, Daniele Di Giulio Cesare, Sonia Di Lemme, Chiara Di Tillio, Teresa Fonsdituri, Ilaria Maietta, Agata Marchese, Silvia Marinetto, Federica Martini, Cristiana Morano, Silvia Perugini, Giovanna Ramona Piredda, Chiara Raimondi, Ilaria Rossi, Valentina Tallarico, Stefania Treccarichi   +47 more
wiley   +1 more source