Results 51 to 60 of about 87,037 (303)
Brief versus long maternal separation in lactating rats: Consequences on maternal behavior, emotionality, and brain oxytocin receptor binding [PDF]
, 2023 Maternal separation is a widely used animal model to study early life adversity in offspring. However, only a few studies have focused on the impact of disrupting the maternal bond from the mother's perspective.
Bosch, Oliver J. +2 more
core +1 more source
AntioxidantsEarly life stress (ELS) is a risk factor for the development of chronic diseases resulting from functional alterations of organs in the cardiorespiratory and renal systems. This work studied the changes in oxidative stress enzyme activities (EAs) of SOD,
Bertha Fenton Navarro +4 more
doaj +1 more source
Knowledge Summary 22: Reaching Child Brides [PDF]
, 2012 Child marriage affects 10 million girls under the age of 18 every year. The negative health and social impact of child marriage include higher rates of maternal and infant mortality, sexually transmitted infection, social separation, and domestic abuse
Partnership for Maternal, Newborn and Child Health
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Maternal separation alters glucocorticoid signaling in the nucleus accumbens of female mice
, 2015 Early life stress (ELS) has been identified as a significant contributing factor in numerous neuropsychiatric disorders. In fact exposure to multiple traumatic early life events (4 + ) increases the risk of developing alcohol use disorders 7 fold and ...
Johnson, Luke +2 more
core +1 more source
Perinatal Stress and Methamphetamine Exposure Decreases Anxiety-Like Behavior in Adult Male Rats
Frontiers in Behavioral Neuroscience, 2021 Methamphetamine (MA) is an illicit synthetic psychostimulant drug, and its abuse is growing worldwide. MA has been reported as the primary drug of choice, by drug-abusing women, during pregnancy.
Anna Holubová-Kroupová +1 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Huli yanjiu, 2022 ObjectiveTo explore the influence of pregnancy stress and coping style on delayed onset of lactogenesis in maternal separation.MethodsA total of 154 parturients with mother⁃to⁃child separation were surveyed by using the general information questionnaire ...
LU Yi, YIN Ying, JIANG Hui
doaj
Frontiers in Psychiatry, 2021 Our aims were to evaluate the depression model of early maternal separation (MS) combined with adolescent chronic unpredictable mild stress (CUMS) in female adult SD rats to observe the behavior and the expressions of synaptic proteins in rats and to ...
Jiawen Huang +7 more
doaj +1 more source