Results 51 to 60 of about 1,453,231 (297)

Generative AI Utilization and Perspectives Among Reproductive‐Age Women with Systemic Autoimmune and Rheumatic Diseases

Arthritis Care &Research, Accepted Article.
Objective Reproductive‐age women with systemic autoimmune and rheumatic diseases (SARDs) have unique information needs related to their SARDs and reproductive health. We sought to understand their use of and receptivity to current and hypothetical generative artificial intelligence (AI) tools for health information‐seeking. Methods We conducted a cross‐
Mariam Arif, Catherine Wright, Samantha Rodriguez, Sarah Graves, Tamar Krishnamurti, Mehret Birru Talabi   +5 more
wiley   +1 more source

The Association between Exclusive Breastfeeding, Maternal Nutritional Status, Maternal Zinc Intake, and Stunting in Infants Aged 6 Months [PDF]

, 2020
Background: Stunting is a form of malnutrition that has an impact on decreased learning achie­ve­ment, motor and mental development and intellectual.
Salimo, Harsono, Dewi, Yulia Lanti Retno, Anindya, Ivanda Glanny   +2 more
core  

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐Shielded Heart Valves

Advanced Healthcare Materials, EarlyView.
Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune‐evasion genes US2 and Serpin b9 into donor valve cells and valve tissue suppresses HLA expression, reduces PBMC clustering and cytotoxic killing, and induces transcriptional immune‐tolerance programs, paving the ...
Abraham van Wijk, Leanne Van den Berg, Isa B. M. Velraeds, Valentina Osorio Zuluaga, Emma T. M. Peereboom, Martijn J. W. E. Rabelink, Arnaud Zaldumbide, Rob C. Hoeben, Marie‐Jose T. H. Goumans, Eric Spierings, Carlijn V. C. Bouten, Marijn C. Peters   +11 more
wiley   +1 more source

Examination of the role of adrenergic receptor stimulation in the sensitization of neuroinflammatory-based depressive-like behavior in isolated Guinea pig pups

Stress, 2023
Early-life attachment disruption appears to sensitize neuroinflammatory signaling to increase later vulnerability for stress-related mental disorders, including depression.
Rachel R. Kessler, Patricia A. Schiml, Sean M. McGraw, Erin N. Tomlin, Mikayla J. Hoeferlin, Terrence Deak, Michael B. Hennessy   +6 more
doaj   +1 more source

The Behavioral and Immunological Impact of Maternal Separation: A Matter of Timing [PDF]

Frontiers in Behavioral Neuroscience, 2014
Maternal separation (MS), an early life stressful event, has been demonstrated to trigger neuropsychiatric disorders later in life, in particular depression. Experiments using rodents subjected to MS protocols have been very informative for the establishment of this association.
Susana eRoque, Susana eRoque, Ana Raquel Mesquita, Ana Raquel Mesquita, Joana A Palha, Joana A Palha, Nuno eSousa, Nuno eSousa, Margarida eCorreia-Neves, Margarida eCorreia-Neves   +9 more
openaire   +4 more sources

Spatial Control of Light‐Responsive Proteins and Optogenetics Within Hydrogels via Volumetric Bioprinting

Advanced Materials, EarlyView.
Spatiotemporal control over cell behavior within bioprinted constructs remains a key challenge in biofabrication. Volumetric bioprinting using multi‐wavelength light sources permits to activate light‐sensitive intracellular proteins as well as optogenetic gene and protein expression circuits in bioprinted cells, in addition to enabling fast printing of
Davide Ribezzi, Pere Català, Gabriel Größbacher, Paulina Nuñez Bernal, Olaf Nijssen, Sammy Florczak, Wilco Nijenhuis, Nuria Crusellas‐Villorbina, Bram Nijhoff, Paul Delrot, Jos Malda, Andreas Hierholzer, Martin Fussenegger, Lukas C. Kapitein, Riccardo Levato   +14 more
wiley   +1 more source

Assessing Degree of maternal separation anxiety in working women who put their first child to kindergartens of Universities of Medical Sciences in Tehran, 1994

نشریه پرستاری ایران, 1995
This field study was conducted on 60 women who working in related centers of Universities of Medical Sciences in Tehran. Data gathering tool was maternal separation anxiety questionnaire that designated by Hock & et al. (1982).
Rouhani, K, , , ,
doaj  

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

Advanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang, Junxiang Ji, Baoxing Dong, Zhenhua Zhu, Xucheng Lv, Peng Chen, Wenqiang Liu, Min Zhou, Shou‐Dong Ye   +8 more
wiley   +1 more source

Possible Effects of Early Maternal Separation on the Gut Microbiota of Captive Adult Giant Pandas

Animals, 2022
Maternal deprivation (MD) in early life induces dysbiosis in the host gut microbiota, which is a key determinant of abnormal behavior in stress model individuals.
Xiaohui Zhang, Xueying Wang, James Ayala, Yuliang Liu, Junhui An, Donghui Wang, Zhigang Cai, Rong Hou, Mingyue Zhang   +8 more
doaj   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source