Cognitive, emotional and neurochemical effects of repeated maternal separation in adolescent rats [PDF]
As an adverse early life experience, maternal separation (MS) induces profound neurochemical, cognitive and emotional dysfunction. Previous studies have reported that MS affected prepulse inhibition (PPI), anxiety-related behaviors, dopaminergic and ...
Wang, Weiwen +5 more
core
Maternal Separation and Emotional Reactivity in Balb/C Mice [PDF]
9 litters of BALB/c mice were divided into 3 groups: (a) a maternal separation group placed in an incubator during separation, (b) a non-incubated separation group, and (c) a non-separated control group. Beginning 24 hr.
Richard C. La Barba +2 more
core +1 more source
The effect of mandatory treadmill exercise on anxiety-like behaviors and bowel oxidative stress following the maternal separation stress in male rats [PDF]
Background: Anxiety has been identified as the most common mental health disorder and 30% of psychological disorders in societies are due to early-life stress. The aim of this study was to investigate the effect of mandatory exercise on anxiety and bowel
A Khoorjahani, M Peeri, MA Azarbayjani
doaj
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane +43 more
wiley +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Maternal separation induces alterations of serotonergic system in different aged rats [PDF]
Maternal separation (MS) induces profound behavioral and neurochemical dysregulations in adult rodents. In the present longitudinal study, we investigated the effects of repeated (4 h/day) maternal separation during postnatal days 1-21 on serotonergic ...
Wang, Weiwen +4 more
core
The Impact of Pandemic-Induced Separation and Visitation Restrictions on the Maternal-Infant Dyad in Neonatal Units: A Systematic Review [PDF]
Background: The COVID-19 pandemic affected the maternal-infant dyad, especially due to visitation restrictions in neonatal units. These changes may impact the psychological, physical, and developmental health of mothers and newborns.
Phumdoung, Sasitorn +3 more
core +1 more source
Maternal Separation Anxiety in Hispanic and Euro-American Mothers [PDF]
Maternal separation anxiety, that is, anxiety experienced by mothers when separated from their infants, was compared for 24 Hispanic and 41 Euro-American mothers.
Elizabeth Morgan Russell +2 more
core +1 more source
Early-life attachment disruption appears to sensitize neuroinflammatory signaling to increase later vulnerability for stress-related mental disorders, including depression.
Rachel R. Kessler +6 more
doaj +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source

