Results 81 to 90 of about 89,266 (344)

Neuropeptides as mediators of the early-life impact on the brain; implications for alcohol use disorders

Frontiers in Molecular Neuroscience, 2012
The brain is constantly exposed to external and internal input and to function in an ever-changing environment we are dependent on processes that enable the brain to adapt to new stimuli.
Ingrid eNylander, Erika eRoman
doaj   +1 more source

Neonatal Tactile Stimulations Affect Genetic Generalized Epilepsy and Comorbid Depression-Like Behaviors

Frontiers in Behavioral Neuroscience, 2020
Recent studies suggest that development of absence epilepsy and comorbid depression might be prevented by increased maternal care of the offspring, in which tactile stimulation induced by licking/grooming and non-nutritive contact seem to be crucial.
Aymen Balikci, Gul Ilbay, Nurbay Ates
doaj   +1 more source

Probiotic Bifidobacterium bifidum G9-1 Has a Preventive Effect on the Acceleration of Colonic Permeability and M1 Macrophage Population in Maternally Separated Rats

Biomedicines, 2021
Although probiotics may be useful for the treatment of irritable bowel syndrome (IBS), it is unclear how probiotics play a role in colonic mucosal integrity and immunity.
Xuan Wang, Hirokazu Fukui, Ying Ran, Xin Xu, Nobuhiko Ebisutani, Takashi Nakanishi, Yoshiki Tanaka, Ayako Maeda, Yutaka Makizaki, Toshihiko Tomita, Tadayuki Oshima, Hiroto Miwa   +11 more
doaj   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Methylation of NR3C1 is related to maternal PTSD, parenting stress and maternal medial prefrontal cortical activity in response to child separation among mothers with histories of violence exposure. [PDF]

, 2015
Prior research has shown that mothers with Interpersonal violence-related posttraumatic stress disorder (IPV-PTSD) report greater difficulty in parenting their toddlers.
Ansermet, Francois, Sancho Rossignol, Ana, Gaëlle Merminod, María I. Cordero, Aue Seil, Tatjana, Dayer, Alexandre, Rusconi Serpa, S, Merminod, G, Adouan, W, Francesca eSuardi, Cordero Campana, Maria Isabel, Moser, DA, Paoloni-Giacobino, Ariane, Ana eSancho Rossignol, Schechter, Daniel, Gaëlle eMerminod, Marianne Gex-Fabry, Alexandre eDayer, Ariane ePaoloni-Giacobino, Francois Ansermet, Gex-Fabry, M, Aue, T, Paoloni-Giacobino, A, Giacobino, Ariane, Dayer, Alexandre G, Dominik A. Moser, Merminod, Gaëlle, Ana Sancho Rossignol, Sancho P. Sousa Rossignol, Ana Cristina, Francois eAnsermet, Suardi, Francesca, Rusconi Serpa, Sandra, Sandra Rusconi Serpa, Dominik Andreas Moser, Gex-Fabry, Marianne, Cordero, MI, Manini, Aurelia Céline, Dayer, AG, María I Cordero, Francesca Suardi, Moser, Dominik A, Cordero, María I, Aurelia Manini, Suardi, F, Sancho Rossignol, A, Ansermet, F, Tatjana Aue, Schechter, DS, Tatjana eAue, Wafae eAdouan, Wafae Adouan, Adouan, Wafae, Manini, A, Aue, Tatjana, Daniel Scott Schechter, Sandra eRusconi Serpa, Schechter, Daniel S, Ludwig Stenz, Alexandre G. Dayer, Daniel S. Schechter, Manini, Aurelia, Ludwig eStenz, Stenz, Ludwig, Marianne eGex-Fabry, Aurelia eManini, Moser, Dominik, Stenz, L, Ariane Paoloni-Giacobino   +67 more
core   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

El maltrato infantil: mecanismos subyacentes

Avances en Psicología Latinoamericana, 2008
Exposure to traumatic stress during childhood, in the form of abuse or neglect, is related to an increased vulnerability resulting in the development of several pathologies, this relation has been confirmed by epidemiological studies; however, the neural
Martínez, Gladys S.
doaj  

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Early Adolescent Separation Anxiety and Maternal Interactions. [PDF]

, 1985
Attachment and separation in early adolescence were examined relative to maternal/child interactions and school achievement. Separation anxiety was measured by the Separation Anxiety Test, perceived maternal rejection and intrusiveness by the Child ...
Ardizzone, John Richard
core  

On the origin of trisomy 21 Down syndrome [PDF]

, 2008
Background: Down syndrome, characterized by an extra chromosome 21 is the most common genetic cause for congenital malformations and learning disability.
Nikos Papadogiannakis, Maj A Hultén, Papadogiannakis, Nikos, Westgren, Magnus, Jonsson, Anna Maria, Tankimanova, Maira, Patel, Suketu D., Iwarsson, Erik, Maira Tankimanova, Anna Jonsson, Magnus Westgren, Erik Iwarsson, Hultén, Maj A., Suketu D Patel   +13 more
core   +1 more source