Results 61 to 70 of about 2,028,316 (397)

Maternal separation prior to neonatal hypoxia-ischemia: Impact on emotional aspects of behavior and markers of synaptic plasticity in hippocampus [PDF]

, 2016
Exposure to early-life stress is associated with long-term alterations in brain and behavior, and may aggravate the outcome of neurological insults. This study aimed at investigating the possible interaction between maternal separation, a model of early ...
Anderson C.A., Anestis Ioannidis, Constantina Simeonidou, Despina Α. Tata, Evangelia Nousiopoulou, Evangelia Spandou, Evgenia Dandi, Handel M., Herrera‐Marschitz M., Huot R.L., Ioanna Markostamou, Kostopoulou E., Madrigal J.L., Maria‐Aikaterini Mandyla, Pascual R., Paxinos G., Tata D.A., Volpe J.J., Wigger a   +18 more
core   +2 more sources

The effect of mandatory treadmill exercise on anxiety-like behaviors and bowel oxidative stress following the maternal separation stress in male rats [PDF]

فصلنامه ابن سینا, 2018
Background: Anxiety has been identified as the most common mental health disorder and 30% of psychological disorders in societies are due to early-life stress. The aim of this study was to investigate the effect of mandatory exercise on anxiety and bowel
A Khoorjahani, M Peeri, MA Azarbayjani
doaj  

Early life stress influences basal ganglia dopamine receptors and novel object recognition of adolescent and adult rats

IBRO Neuroscience Reports, 2022
Environmental stimuli in early life are recognized to affect brain development and behavior. Mother-pup interaction constitutes a determinant stimulus during this critical period.
Ada Sinani, Andriana Vassi, Giota Tsotsokou, Maria Nikolakopoulou, Elias D. Kouvelas, Ada Mitsacos   +5 more
doaj  

Maternal Separation Induced Visceral Hypersensitivity Evaluated via Novel and Small Size Distention Balloon in Post-weaning Mice

Frontiers in Neuroscience, 2022
Early life stress (ELS) disposes to functional gastrointestinal diseases in adult, such as irritable bowel syndrome (IBS). Maternal separation (MS) is a well-known animal model of IBS and has been shown to induce visceral hypersensitivity in adult rats ...
Enfu Tao, Enfu Tao, Gao Long, Ting Yang, Bo Chen, Rui Guo, Diya Ye, Marong Fang, Mizu Jiang   +8 more
doaj   +1 more source

Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors

Molecular Oncology, EarlyView.
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi, Janelle‐Cheri Millen, Romela Irene Ramos, Jennifer A. Linehan, Timothy G. Wilson, Dave S. B. Hoon, Matias A. Bustos   +6 more
wiley   +1 more source

Qué sabemos sobre las consecuencias a largo plazo de la separación materna temprana y la respuesta neuroendocrina al estrés [PDF]

, 2014
Adverse conditions during early life are a risk factor for stress-related diseases. How this early adversity induce long-term effects is not well understood, however there are several evidence that the stress hormones play a determining role.
Renard, Georgina Maria, Rivarola, María Angélica   +1 more
core  

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

First-trimester combined screening for trisomy 21 at 7-14 weeks' gestation. [PDF]

, 2010
OBJECTIVE: To establish an algorithm for first-trimester combined screening for trisomy 21 with biochemical testing from 7 to 14 weeks' gestation and ultrasound testing at 11-13 weeks. METHODS: This was a multicenter study of 886 pregnancies with trisomy
Borrell, Cuckle, Draper, Kagan, Kagan, Kirkegaard, Loughna, Office for National Statistics, Souka, Spencer, Spencer, Wright   +11 more
core   +1 more source

Transcriptome Analysis on Maternal Separation Rats With Depression-Related Manifestations Ameliorated by Electroacupuncture

Frontiers in Neuroscience, 2019
Maternal separation (MS), a stressful event in early life, has been linked to neuropsychiatric disorders later in life, especially depression. In this study we investigated whether treatment with electroacupuncture (EA) could ameliorate depression ...
Yuanjia Zheng, Jiang He, Lili Guo, Lin Yao, Xiaorong Zheng, Zhihua Yang, Yucen Xia, Xiaoli Wu, Yang Su, Nenggui Xu, Yongjun Chen   +10 more
semanticscholar   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source