Results 61 to 70 of about 159,993 (313)

Estimating the duration of seropositivity of human seasonal coronaviruses using seroprevalence studies [version 1; peer review: 1 approved, 2 approved with reservations]

open access: yesWellcome Open Research, 2021
Background: The duration of immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is still uncertain, but it is of key clinical and epidemiological importance.
Eleanor M. Rees   +4 more
doaj   +1 more source

A View of Mathematical Modeling in Mathematics Education

open access: yes, 2013
Journal of Mathematics Education at Teachers College, 2013: Proceedings: Conference on Mathematical ...
Henry Pollak, Sol Garfunkel
openaire   +3 more sources

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Learning Mathematical Modelling

open access: yes, 2016
To teach mathematical modelling to prospective upper secondary teachers is not trivial. Since the Swedish curriculum from 2011 recommends mathematical modelling for all students who study major courses in mathematics in upper secondary school, only the ...
Lingefjärd, Thomas,
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Building HPC Expertise: Training Initiatives of the Polish National Competence Centre

open access: yesTASK Quarterly
The EuroCC is a flagship project of the EuroHPC initiative intended to establish a network of National Competence Centers (NCCs) across participating member states.
Joanna Jędraszczyk, Michał Hermanowicz
doaj   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Structural stability of the hepatitis C model with the proliferation of infected and uninfected hepatocytes

open access: yesMathematical and Computer Modelling of Dynamical Systems
The structural stability of the hepatitis C model with the proliferation of infected and uninfected hepatocytes is investigated in this paper. The model is clinically verified to accurately reflect the viral dynamics of hepatitis C.
Z. Navickas   +4 more
doaj   +1 more source

Improving Air Pollution Modelling in Complex Terrain with a Coupled WRF–LOTOS–EUROS Approach: A Case Study in Aburrá Valley, Colombia

open access: yesAtmosphere, 2023
Chemical transport models (CTM) are crucial for simulating the distribution of air pollutants, such as particulate matter, and evaluating their impact on the environment and human health.
Jhon E. Hinestroza-Ramirez   +7 more
doaj   +1 more source

On the Mathematics of Diffusion Models

open access: yesCoRR, 2023
This paper gives direct derivations of the differential equations and likelihood formulas of diffusion models assuming only knowledge of Gaussian distributions. A VAE analysis derives both forward and backward stochastic differential equations (SDEs) as well as non-variational integral expressions for likelihood formulas.
openaire   +2 more sources

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