Results 41 to 50 of about 16,332,590 (301)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Making mathematics meaningful: Using student-initiated problems to situate mathematics [PDF]
, 2014 Mathematics is everywhere-from the minute we open our eyes to check the alarm clock and calculate how many minutes extra we can afford to lie in bed, to measuring out our cereal for breakfast and estimating if we have enough petrol to make the 18 ...
Brough, Chris Jane, Calder, Nigel Stuart
core
Proceedings of the Annual Meeting of the Georgia Association of Mathematics Teacher EducatorsThe purpose of GAMTE is to encourage and facilitate the improvement of mathematics teacher education across the state of Georgia. The goals of the organization are to: facilitate communication and collaboration among mathematics teacher educators between
Georgia Association of Mathematics Teacher Educators
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Maori preservice primary teachers’ responses to mathematics investigations [PDF]
, 2006 There has been concern for some years about the low mathematics achievement of Maori students in New Zealand. This case study reports on the responses of 18 Maori preservice teachers to investigative approaches to learning mathematics during their ...
Hāwera, Ngārewa
core +1 more source
Kaspar Schott’s “encyclopedia of all mathematical sciences” [PDF]
Poiesis & Praxis, 2011 In 1661, Kaspar Schott published his comprehensive textbook "Cursus mathematicus" in Würzburg for the first time, his "Encyclopedia of all mathematical sciences". It was so successful that it was published again in 1674 and 1677. In its 28 books, Schott gave an introduction for beginners in 22 mathematical disciplines by means of 533 figures and ...
openaire +3 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
All Day Mathematics Workshops [PDF]
2001 Annual Conference Proceedings, 2020 Comment: 10 ...
Lindsey Van Wagenen, Chandni Shah
openaire +2 more sources