Sedative Effect ofSophora flavescensand Matrine [PDF]
Biomolecules & Therapeutics, 2017 The present study investigated the sedative effects of Sophora flavescens (SF) and its bioactive compound, matrine through performing locomotor activity test and the electroencephalography (EEG) analysis in the rat. The underlying neural mechanism of their beneficial effects was determined by assessing c-Fos immunoreactivity and serotonin (5-HT) in the
Lee, Hyun-ju +4 more
openaire +2 more sources
Heat Therapy: Targeting Health, Disease, and Disability
Comprehensive Physiology, Volume 16, Issue 1, February 2026.The predominance of evidence suggests heat therapy has an impact on all aspects of health and performance, but the drivers of that improvement, the extent to which they are improved, and the specific populations in which improvements manifest are far from completely understood.
Rauchelle E. Richey +5 more
wiley +1 more source
Anticancer effect of a combination of cisplatin and matrine on cervical cancer U14 cells and U14 tumor-bearing mice, and possible mechanism of action involved [PDF]
, 2022 Purpose: To investigate the anticancer effects of cisplatin (DDP) in combination with matrine on cervical cancer U14 cell tumor-bearing mice. Methods: The cell proliferation of cervical cancer U14 cells treated with DDP (25, 20, 15, 10 and 5 μg/mL ...
Bai, Xuefei +7 more
core +2 more sources
Exosome-mimetic vesicles derived from fibroblasts carrying matrine for wound healing
Burns & TraumaBackground Chronic skin wounds are a leading cause of hospital admissions and reduced life expectancy among older people and individuals with diabetes. Delayed wound healing is often attributed to a series of cellular abnormalities.
Xinyue Zhang +9 more
semanticscholar +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
Isolation and identification of a matrine-producing fungal strain from petroleum-contaminated soil
浙江大学学报. 农业与生命科学版, 2015 Matrine is one of the quinolizidine alkaloids. It is widely used as broad-spectrum agricultural pesticides, which exists mainly in roots of leguminous plants.
Mao Dongxia +6 more
doaj +1 more source
Synthesis of Halopyrazole Matrine Derivatives and Their Insecticidal and Fungicidal Activities
Molecules, 2022 Matrine is a traditional botanical pesticide with a broad-spectrum biological activity that is widely applied in agriculture. Halopyrazole groups are successfully introduced to the C13 of matrine to synthesize eight new derivatives with a yield of 78–87%.
Xingan Cheng +9 more
doaj +1 more source
Celecoxib in breast cancer prevention and therapy. [PDF]
, 2018 Breast cancer has a high incidence worldwide. The results of substantial studis reveal that inflammation plays an important role in the initiation, development, and aggressiveness of many malignancies. The use of celecoxib, a novel NSAID, is repetitively
Cao, Wei +4 more
core
Autophagy: A cyto-protective mechanism which prevents primary human hepatocyte apoptosis during oxidative stress [PDF]
, 2012 The role of autophagy in the response of human hepatocytes to oxidative stress remains unknown. Understanding this process may have important implications for the understanding of basic liver epithelial cell biology and the responses of hepatocytes ...
Biederbick A +7 more
core +1 more source
Marine Life Science & TechnologyEczema is a common chronic dermatological disease. Conventional treatments exhibit limited efficacy due to fast drug release resulting in short-term relief.
Jiale Shen +6 more
semanticscholar +1 more source