Some aspects of radical chemistry in the assembly of complex molecular architectures
International audienceThis review article describes briefly some of the radical processes developed in the authors' laboratory as they pertain to the concise assembly of complex molecular scaffolds.
Quiclet-Sire, Beatrice, Zard, Samir,
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Impact of Endothelial Diversity and Dysfunction on Cardiovascular Disease
The vascular endothelium is highly diverse, regulating permeability, vascular tone, repair, and inter‐organ communication. Endothelial heterogeneity supports tissue‐specific needs, but dysfunction drives cardiovascular disease. Transcriptomics, in vitro models, and redox signaling studies reveal therapeutic targets for precision treatment of ...
Anna E. Williams +6 more
wiley +1 more source
A method was developed for the determination of matrine residues in quinoa (Chenopodium quinoa Willd.) plants and soil by liquid chromatography triple quadrupole tandem mass spectrometry (LC-MS/MS) with QuEChERS clean-up. Matrine from soil, quinoa roots,
Xiangjuan Hui +4 more
doaj +1 more source
The Role of Matrine and Mitogen-Ativated Protein Kinase/Extracellular Signal-Regulated Kinase Signal Transduction in the Inhibition of the Proliferation and Migration of Human Umbilical Veins Endothelial Cells Induced by Lung Cancer cells [PDF]
Background and objective Matrine, one of the major alkaloid components of the traditional Chinese medicine Sophora roots, has a wide range of pharmacological effects including anti-inflammatory activities, growth inhibition and induction of cell ...
Jinchang LU +5 more
core
The integration of a multidimensional treatment dominated by active ingredients of traditional Chinese medicine (TCM), including enhanced chemotherapy and synergistically amplification of oxidative damage, into a nanoplatform would be of great ...
Sitong Lai +7 more
semanticscholar +1 more source
Target Discovery of Matrine against PRRSV in Marc-145 Cells via Activity-Based Protein Profiling
Porcine reproductive and respiratory syndrome (PRRS) seriously endangers the sustainable development of the pig industry. Our previous studies have shown that matrine can resist porcine reproductive and respiratory syndrome virus (PRRSV) infection.
Xiaoya Ling +10 more
semanticscholar +1 more source
Overview of acute Chinese medicine poisoning in Hong Kong
Abstract Background Chinese medicine (CM) poisoning is relatively rare in Hong Kong. According to the Department of Health, only 17 cases of self‐medicated Traditional Chinese Medicine (TCM)‐related poisoning were reported between 2019 and 2021—an average of approximately 5.7 cases per year.
Siu Kan Law, Yanping Wang, Xiao Xiao Wu
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Effect of matrine on proliferation and migration of human thyroid cancer cell line TPC-1 [PDF]
Objective To investigate the mechanism of matrine inhibiting the proliferation and migration of thyroid cancer cell line TPC-1 through down-regulated miRNA-182-5p TPC-1. Methods TPC-1 cells were transfected after 24 hours with 0.5 mg/mL matrine or
FU Song-bo, MA Cheng-xu, JING Gao-jing, ZHAO Nan, TANG Xu-lei, MOU Jun-qin, CHANG Yin-long
doaj
Research Advancements in Pharmacological Activities and Mechanisms of Matrine
Matrine possesses a broad spectrum of pharmacological activities as one of the primary components of Chinese herbal medicine Sophora flavescens extract, along with fewer side effects and low toxicity.
Xiaohui Chen +3 more
semanticscholar +1 more source
Microbiota‐gut‐brain axis multi‐organ chip construction and applications in drug evaluation
Microbiota‐gut‐brain axis multiorgan chip and its applications in drug evaluation. The chip includes essential biological components such as gut microbiota, gut barrier, blood‐brain barrier (BBB), and brain. This integrated platform incorporates neural (blue), endocrine (yellow), immune (pink), and metabolic (green) pathways to investigate the impact ...
Yue Tang +9 more
wiley +1 more source

