Results 81 to 90 of about 9,281 (250)

Some aspects of radical chemistry in the assembly of complex molecular architectures

open access: yes, 2013
International audienceThis review article describes briefly some of the radical processes developed in the authors' laboratory as they pertain to the concise assembly of complex molecular scaffolds.
Quiclet-Sire, Beatrice, Zard, Samir,
core   +4 more sources

Impact of Endothelial Diversity and Dysfunction on Cardiovascular Disease

open access: yesComprehensive Physiology, Volume 15, Issue 6, December 2025.
The vascular endothelium is highly diverse, regulating permeability, vascular tone, repair, and inter‐organ communication. Endothelial heterogeneity supports tissue‐specific needs, but dysfunction drives cardiovascular disease. Transcriptomics, in vitro models, and redox signaling studies reveal therapeutic targets for precision treatment of ...
Anna E. Williams   +6 more
wiley   +1 more source

Establishment of Residual Methods for Matrine in Quinoa Plants and Soil and the Effect on Soil Bacterial Community and Composition

open access: yesFoods, 2023
A method was developed for the determination of matrine residues in quinoa (Chenopodium quinoa Willd.) plants and soil by liquid chromatography triple quadrupole tandem mass spectrometry (LC-MS/MS) with QuEChERS clean-up. Matrine from soil, quinoa roots,
Xiangjuan Hui   +4 more
doaj   +1 more source

The Role of Matrine and Mitogen-Ativated Protein Kinase/Extracellular Signal-Regulated Kinase Signal Transduction in the Inhibition of the Proliferation and Migration of Human Umbilical Veins Endothelial Cells Induced by Lung Cancer cells [PDF]

open access: yes, 2009
Background and objective Matrine, one of the major alkaloid components of the traditional Chinese medicine Sophora roots, has a wide range of pharmacological effects including anti-inflammatory activities, growth inhibition and induction of cell ...
Jinchang LU   +5 more
core  

Self-Assembled Matrine-PROTAC Encapsulating Zinc(II) Phthalocyanine with GSH-Depletion-Enhanced ROS Generation for Cancer Therapy

open access: yesMolecules
The integration of a multidimensional treatment dominated by active ingredients of traditional Chinese medicine (TCM), including enhanced chemotherapy and synergistically amplification of oxidative damage, into a nanoplatform would be of great ...
Sitong Lai   +7 more
semanticscholar   +1 more source

Target Discovery of Matrine against PRRSV in Marc-145 Cells via Activity-Based Protein Profiling

open access: yesInternational Journal of Molecular Sciences, 2023
Porcine reproductive and respiratory syndrome (PRRS) seriously endangers the sustainable development of the pig industry. Our previous studies have shown that matrine can resist porcine reproductive and respiratory syndrome virus (PRRSV) infection.
Xiaoya Ling   +10 more
semanticscholar   +1 more source

Overview of acute Chinese medicine poisoning in Hong Kong

open access: yesHong Kong Journal of Emergency Medicine, Volume 32, Issue 6, December 2025.
Abstract Background Chinese medicine (CM) poisoning is relatively rare in Hong Kong. According to the Department of Health, only 17 cases of self‐medicated Traditional Chinese Medicine (TCM)‐related poisoning were reported between 2019 and 2021—an average of approximately 5.7 cases per year.
Siu Kan Law, Yanping Wang, Xiao Xiao Wu
wiley   +1 more source

Effect of matrine on proliferation and migration of human thyroid cancer cell line TPC-1 [PDF]

open access: yesJichu yixue yu linchuang, 2021
Objective To investigate the mechanism of matrine inhibiting the proliferation and migration of thyroid cancer cell line TPC-1 through down-regulated miRNA-182-5p TPC-1. Methods TPC-1 cells were transfected after 24 hours with 0.5 mg/mL matrine or
FU Song-bo, MA Cheng-xu, JING Gao-jing, ZHAO Nan, TANG Xu-lei, MOU Jun-qin, CHANG Yin-long
doaj  

Research Advancements in Pharmacological Activities and Mechanisms of Matrine

open access: yesPharmacognosy Magazine, 2023
Matrine possesses a broad spectrum of pharmacological activities as one of the primary components of Chinese herbal medicine Sophora flavescens extract, along with fewer side effects and low toxicity.
Xiaohui Chen   +3 more
semanticscholar   +1 more source

Microbiota‐gut‐brain axis multi‐organ chip construction and applications in drug evaluation

open access: yesiMetaOmics, Volume 2, Issue 4, December 2025.
Microbiota‐gut‐brain axis multiorgan chip and its applications in drug evaluation. The chip includes essential biological components such as gut microbiota, gut barrier, blood‐brain barrier (BBB), and brain. This integrated platform incorporates neural (blue), endocrine (yellow), immune (pink), and metabolic (green) pathways to investigate the impact ...
Yue Tang   +9 more
wiley   +1 more source

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